Exosomes Mediate Hippocampal and Cortical Neuronal Injury Induced by Hepatic Ischemia-Reperfusion Injury through Activating Pyroptosis in Rats

Extracellular Vesicle-Mediated Cell–Cell Communication in the Nervous System: Focus on Neurological Diseases

(2019) Celeste Caruso Bavisotto et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells

(2019) Souvarish Sarkar et al.   Science Signaling

A Mouse Model of Hepatic Ischemia-Reperfusion Injury Demonstrates Potentially Reversible Effects on Hippocampal Neurons and Postoperative Cognitive Function

(2019) Weiwei Wu et al.   MEDICAL SCIENCE MONITOR

The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury

(2019) Stephanie W. Lee et al.   Journal of Neuroinflammation

Leukemia-derived exosomes and cytokines pave the way for entry into the brain

(2019) Ichiko Kinjyo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo

(2019) Frederik J. Verweij et al.   DEVELOPMENTAL CELL

Embryonic stem cell-derived exosomes inhibit doxorubicin-induced TLR4-NLRP3-mediated cell death-pyroptosis

(2019) Zahra Tavakoli Dargani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Reduction of myocardial ischaemia–reperfusion injury by inactivating oxidized phospholipids

(2018) Calvin Yeang et al.   CARDIOVASCULAR RESEARCH

Pioglitazone Confers Neuroprotection Against Ischemia-Induced Pyroptosis due to its Inhibitory Effects on HMGB-1/RAGE and Rac1/ROS Pathway by Activating PPAR-ɤ

(2018) Pingping Xia et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Interferon regulatory factor 1-Rab27a regulated extracellular vesicles promote liver ischemia/reperfusion injury

(2018) Mu-qing Yang et al.   HEPATOLOGY

Inflammasome: Its role in traumatic brain and spinal cord injury

(2018) Keywan Mortezaee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

In vivo evidence for the contribution of peripheral circulating inflammatory exosomes to neuroinflammation

(2018) Jing Jing Li et al.   Journal of Neuroinflammation

Ablation of caspase-1 protects against TBI-induced pyroptosis in vitro and in vivo

(2018) Wei Liu et al.   Journal of Neuroinflammation

Evidence that NLRC4 Inflammasome Mediates Apoptotic and Pyroptotic Microglial Death Following Ischemic Stroke

(2018) Luting Poh et al.   BRAIN BEHAVIOR AND IMMUNITY

In situ inflammasome activation results in severe damage to the central nervous system in fatal Zika virus microcephaly cases

(2018) Jorge Rodrigues de Sousa et al.   CYTOKINE

Src is Implicated in Hepatic Ischemia Reperfusion-Induced Hippocampus Injury and Long-Term Cognitive Impairment in Young Mice via NMDA Receptor Subunit 2A Activation

(2018) Xiangyang Yu et al.   NEUROSCIENCE

Ageratina adenophora induces mice hepatotoxicity via ROS-NLRP3-mediated pyroptosis

(2018) Wei Sun et al.   Scientific Reports

Innate immunity as a target for acute cardioprotection

(2018) Coert J Zuurbier et al.   CARDIOVASCULAR RESEARCH

Proteomic Profiling of LPS-Induced Macrophage-Derived Exosomes Indicates Their Involvement in Acute Liver Injury

(2018) Guozhen Wang et al.   PROTEOMICS

AC-YVAD-CMK Inhibits Pyroptosis and Improves Functional Outcome after Intracerebral Hemorrhage

(2018) Xiao Lin et al.   Biomed Research International

A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death

(2018) Shigetoshi Yokoyama et al.   eLife

Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress

(2018) Jianbin Bi et al.   Redox Biology

The role of exosomes in hepatitis, liver cirrhosis and hepatocellular carcinoma

(2017) Jiliang Shen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies

(2017) Limin Song et al.   Frontiers in Cellular Neuroscience

Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation

(2017) Beatrice Oehler et al.   Scientific Reports

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

(2016) Lorenzo Sborgi et al.   EMBO JOURNAL

Exosomes in stroke pathogenesis and therapy

(2016) Zheng Gang Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

(2016) Robin A. Aglietti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles)

(2016) Y Xing et al.   Cell Death & Disease

Increased Brain-Specific MiR-9 and MiR-124 in the Serum Exosomes of Acute Ischemic Stroke Patients

(2016) Qiuhong Ji et al.   PLoS One

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Exosome-mediated inflammasome signaling after central nervous system injury

(2015) Juan Pablo de Rivero Vaccari et al.   JOURNAL OF NEUROCHEMISTRY

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Exosomes in neurological disease, neuroprotection, repair and therapeutics: problems and perspectives

(2015) Anuradha Kalani et al.   Neural Regeneration Research

Evaluation of Early Postoperative Neurological Complications Following Living Donor Liver Transplantation

(2015) Emrah Otan et al.   Noropsikiyatri Arsivi-Archives of Neuropsychiatry

Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

(2014) John G Walsh et al.   Retrovirology

Role of mitochondria ROS generation in ethanol-induced NLRP3 inflammasome activation and cell death in astroglial cells

(2014) Silvia Alfonso-Loeches et al.   Frontiers in Cellular Neuroscience

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury

(2013) Øystein Sandanger et al.   CARDIOVASCULAR RESEARCH

The Molecular Link Between C-C-Chemokine Ligand 2-Induced Leukocyte Recruitment and Hyperalgesia

(2013) Diana Pflücke et al.   JOURNAL OF PAIN

Exosomes: Mediators of Neurodegeneration, Neuroprotection and Therapeutics

(2013) Anuradha Kalani et al.   MOLECULAR NEUROBIOLOGY

The Connection of Monocytes and Reactive Oxygen Species in Pain

(2013) Dagmar Hackel et al.   PLoS One

Oxidized Low Density Lipoprotein Induced Caspase-1 Mediated Pyroptotic Cell Death in Macrophages: Implication in Lesion Instability?

(2013) Jing Lin et al.   PLoS One

Intestinal ischemia/reperfusion enhances microglial activation and induces cerebral injury and memory dysfunction in rats*

(2012) Jun Zhou et al.   CRITICAL CARE MEDICINE

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Senegenin Attenuates Hepatic Ischemia-Reperfusion Induced Cognitive Dysfunction by Increasing Hippocampal NR2B Expression in Rats

(2012) Weibin Xie et al.   PLoS One

Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts

(2011) Hartmut Jaeschke   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Role of interleukin-1β in postoperative cognitive dysfunction

(2010) Mario Cibelli et al.   ANNALS OF NEUROLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Aggravation of post-ischemic liver injury by overexpression of A20, an NF-κB suppressor

(2010) Jiahua Yu et al.   JOURNAL OF HEPATOLOGY

Effect of Liver Ischemia–Reperfusion Injury on the Activity of Neurons in the Rat Brain

(2009) Zdeno Pirnik et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY