Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease

The Molecular Anatomy of Mouse Skin during Hair Growth and Rest

(2020) Simon Joost et al.   Cell Stem Cell

Deciphering the functional heterogeneity of skin fibroblasts using single‐cell RNA sequencing

(2020) Vera Vorstandlechner et al.   FASEB JOURNAL

Single-cell RNA sequencing of human kidney

(2020) Jinling Liao et al.   Scientific Data

Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming

(2020) Llorenç Solé-Boldo et al.   Communications Biology

Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

(2019) Christian F. Guerrero-Juarez et al.   Nature Communications

Defining the Activated Fibroblast Population in Lung Fibrosis Using Single Cell Sequencing

(2019) Rebecca Peyser et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Dual lineage tracing identifies intermediate mesenchymal stage for endocardial contribution to fibroblasts, coronary mural cells and adipocytes

(2019) Xinyan Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct fibroblast subsets drive inflammation and damage in arthritis

(2019) Adam P. Croft et al.   NATURE

Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury

(2019) Nona Farbehi et al.   eLife

Single Cell RNA Sequencing Identifies Subsets of Hepatic Stellate Cells and Myofibroblastsin Liver Fibrosis

(2019) Oliver Krenkel et al.   Cells

Cancer-associated fibroblasts—heroes or villains?

(2019) Krystyna A. Gieniec et al.   BRITISH JOURNAL OF CANCER

Single-cell analysis reveals fibroblast heterogeneity and myofibroblasts in systemic sclerosis-associated interstitial lung disease

(2019) Eleanor Valenzi et al.   ANNALS OF THE RHEUMATIC DISEASES

High-definition spatial transcriptomics for in situ tissue profiling

(2019) Sanja Vickovic et al.   NATURE METHODS

Patch repair of deep wounds by mobilized fascia

(2019) Donovan Correa-Gallegos et al.   NATURE

Functional heterogeneity of resident fibroblasts in the kidney

(2019) Yuki SATO et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1

(2019) Timothy James Kendall et al.   Nature Communications

Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis

(2019) Ross Dobie et al.   Cell Reports

Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome

(2018) Paul Hiebert et al.   DEVELOPMENTAL CELL

Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis

(2018) Nils O. Lindström et al.   DEVELOPMENTAL CELL

Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart

(2018) Xing Fu et al.   JOURNAL OF CLINICAL INVESTIGATION

SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin

(2018) Tracy Tabib et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations

(2018) Christina Philippeos et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring

(2018) Dongsheng Jiang et al.   NATURE CELL BIOLOGY

Phenotype molding of stromal cells in the lung tumor microenvironment

(2018) Diether Lambrechts et al.   NATURE MEDICINE

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

(2018) Jihwan Park et al.   SCIENCE

Skin Cell Heterogeneity in Development, Wound Healing, and Cancer

(2018) Emanuel Rognoni et al.   TRENDS IN CELL BIOLOGY

Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis

(2018) Ting Xie et al.   Cell Reports

Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts

(2018) Peng Hu et al.   GENES & DEVELOPMENT

Lineage identity and location within the dermis determine the function of papillary and reticular fibroblasts in human skin

(2018) Ana Korosec et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors

(2018) Matthew D. Young et al.   SCIENCE

Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging

(2018) Marion Claudia Salzer et al.   CELL

Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair

(2018) Brett A. Shook et al.   SCIENCE

Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing

(2018) Chae Ho Lim et al.   Nature Communications

Redefining the identity of cardiac fibroblasts

(2017) Michelle D. Tallquist et al.   Nature Reviews Cardiology

Regeneration of fat cells from myofibroblasts during wound healing

(2017) Maksim V. Plikus et al.   SCIENCE

Dermal fibroblast in cutaneous development and healing

(2017) Venkata Thulabandu et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Metabolic zonation of the liver: The oxygen gradient revisited

(2017) Thomas Kietzmann   Redox Biology

Defining the Cardiac Fibroblast

(2016) Malina J. Ivey et al.   CIRCULATION JOURNAL

Wound repair: a showcase for cell plasticity and migration

(2016) Tanya J Shaw et al.   CURRENT OPINION IN CELL BIOLOGY

Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing

(2016) Emanuel Rognoni et al.   DEVELOPMENT

Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

(2016) P. L. Stahl et al.   SCIENCE

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

(2016) Onur Kanisicak et al.   Nature Communications

Revisiting Cardiac Cellular CompositionNovelty and Significance

(2015) Alexander R. Pinto et al.   CIRCULATION RESEARCH

The pulmonary mesenchyme directs lung development

(2015) David McCulley et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation

(2015) Grace S. Kaushal et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification and isolation of a dermal lineage with intrinsic fibrogenic potential

(2015) Y. Rinkevich et al.   SCIENCE

Live Fibroblast Harvest Reveals Surface Marker ShiftIn Vitro

(2015) Graham G. Walmsley et al.   TISSUE ENGINEERING PART C-METHODS

Myofibroblasts in Murine Cutaneous Fibrosis Originate From Adiponectin-Positive Intradermal Progenitors

(2015) Roberta Goncalves Marangoni et al.   Arthritis & Rheumatology

Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis

(2014) Joo-Hyeon Lee et al.   CELL

Origin of myofibroblasts in the fibrotic liver in mice

(2014) K. Iwaisako et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance

(2014) L. Hecker et al.   Science Translational Medicine

Distinct fibroblast lineages determine dermal architecture in skin development and repair

(2013) Ryan R. Driskell et al.   NATURE

The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors

(2012) A. Acharya et al.   DEVELOPMENT

Lineage tracing and genetic ablation of ADAM12+ perivascular cells identify a major source of profibrotic cells during acute tissue injury

(2012) Sophie Dulauroy et al.   NATURE MEDICINE

Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice

(2011) Nariaki Asada et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone Deacetylase 2 Is Upregulated in Normal and Keloid Scars

(2011) Edmund J. Fitzgerald O'Connor et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Portal fibroblasts: Underappreciated mediators of biliary fibrosis

(2009) Jonathan A. Dranoff et al.   HEPATOLOGY

Wound repair at a glance

(2009) T. J. Shaw et al.   JOURNAL OF CELL SCIENCE