Redefining the identity of cardiac fibroblasts

Myocardial fibrosis: biomedical research from bench to bedside

(2017) Mariann Gyöngyösi et al.   EUROPEAN JOURNAL OF HEART FAILURE

Phenotyping of myocardial fibrosis in hypertensive patients with heart failure. Influence on clinical outcome

(2017) Susana Ravassa et al.   JOURNAL OF HYPERTENSION

MicroRNA-19b is a potential biomarker of increased myocardial collagen cross-linking in patients with aortic stenosis and heart failure

(2017) Javier Beaumont et al.   Scientific Reports

Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in MiceNovelty and Significance

(2016) Harmandeep Kaur et al.   CIRCULATION RESEARCH

Targeting the Cardiac Myofibroblast Secretome to Treat Myocardial Fibrosis in Heart Failure

(2016) Karl T. Weber et al.   Circulation-Heart Failure

Genetic tools for identifying and manipulating fibroblasts in the mouse

(2016) Jessica M. Swonger et al.   DIFFERENTIATION

Molecular networks underlying myofibroblast fate and fibrosis

(2016) April Stempien-Otero et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mechanical control of cardiac myofibroblasts

(2016) Sander van Putten et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease

(2016) Robert G. Gourdie et al.   NATURE REVIEWS DRUG DISCOVERY

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

(2016) Onur Kanisicak et al.   Nature Communications

Dynamics of Cell Generation and Turnover in the Human Heart

(2015) Olaf Bergmann et al.   CELL

Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

(2015) Rafael Kramann et al.   Cell Stem Cell

Revisiting Cardiac Cellular CompositionNovelty and Significance

(2015) Alexander R. Pinto et al.   CIRCULATION RESEARCH

Loss of SPARC dysregulates basal lamina assembly to disrupt larval fat body homeostasis inDrosophila melanogaster

(2015) Jaffer Shahab et al.   DEVELOPMENTAL DYNAMICS

Cardiac endothelial cells express Wilms' tumor-1

(2015) Sjoerd N. Duim et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac fibroblasts: from development to heart failure

(2015) Thomas Moore-Morris et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Interacting Resident Epicardium-Derived Fibroblasts and Recruited Bone Marrow Cells Form Myocardial Infarction Scar

(2015) Adrián Ruiz-Villalba et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila adipocytes

(2015) Yiran Zang et al.   eLife

Developmental Heterogeneity of Cardiac Fibroblasts Does Not Predict Pathological Proliferation and Activation

(2014) Shah R. Ali et al.   CIRCULATION RESEARCH

Cardiogenic Genes Expressed in Cardiac Fibroblasts Contribute to Heart Development and Repair

(2014) Milena B. Furtado et al.   CIRCULATION RESEARCH

Evaluating the Utility of Circulating Biomarkers of Collagen Synthesis in Hypertrophic Cardiomyopathy

(2014) Andris H. Ellims et al.   Circulation-Heart Failure

Resident fibroblast lineages mediate pressure overload–induced cardiac fibrosis

(2014) Thomas Moore-Morris et al.   JOURNAL OF CLINICAL INVESTIGATION

Fibroblast-mediated pathways in cardiac hypertrophy

(2014) Katsuhito Fujiu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mesenchymal–endothelial transition contributes to cardiac neovascularization

(2014) Eric Ubil et al.   NATURE

c-kit+ cells minimally contribute cardiomyocytes to the heart

(2014) Jop H. van Berlo et al.   NATURE

Lack of specificity of fibroblast-specific protein 1 in cardiac remodeling and fibrosis

(2013) Ping Kong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Coronary adventitial cells are linked to perivascular cardiac fibrosis via TGFβ1 signaling in the mdx mouse model of Duchenne muscular dystrophy

(2013) Nicholas Ieronimakis et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease

(2013) Caitlin M. Braitsch et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Fibroblasts in myocardial infarction: A role in inflammation and repair

(2013) Arti V. Shinde et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myofibroblasts: Trust your heart and let fate decide

(2013) Jennifer Davis et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A host deficiency of discoidin domain receptor 2 (DDR2) inhibits both tumour angiogenesis and metastasis

(2013) Shuya Zhang et al.   JOURNAL OF PATHOLOGY

Cytokine mediated tissue fibrosis

(2012) Lee A. Borthwick et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors

(2012) A. Acharya et al.   DEVELOPMENT

Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart

(2012) Andy Wessels et al.   DEVELOPMENTAL BIOLOGY

A TRPC6-Dependent Pathway for Myofibroblast Transdifferentiation and Wound Healing In Vivo

(2012) Jennifer Davis et al.   DEVELOPMENTAL CELL

Myocardial and circulating levels of microRNA-21 reflect left ventricular fibrosis in aortic stenosis patients

(2012) Ana V. Villar et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Galectin-3, a Marker of Cardiac Fibrosis, Predicts Incident Heart Failure in the Community

(2012) Jennifer E. Ho et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

(2012) Li Qian et al.   NATURE

Myofibroblast-mediated mechanisms of pathological remodelling of the heart

(2012) Karl T. Weber et al.   Nature Reviews Cardiology

Cardiac Regeneration from Activated Epicardium

(2012) Bram van Wijk et al.   PLoS One

Epicardial-Derived Cell Epithelial-to-Mesenchymal Transition and Fate Specification Require PDGF Receptor Signaling

(2011) Christopher L. Smith et al.   CIRCULATION RESEARCH

Shaping Cells and Organs in Drosophila by Opposing Roles of Fat Body-Secreted Collagen IV and Perlecan

(2011) José Carlos Pastor-Pareja et al.   DEVELOPMENTAL CELL

Association of galectin-3 and fibrosis markers with long-term cardiovascular outcomes in patients with heart failure, left ventricular dysfunction, and dyssynchrony: insights from the CARE-HF (Cardiac Resynchronization in Heart Failure) trial

(2011) Natalia Lopez-Andrès et al.   EUROPEAN JOURNAL OF HEART FAILURE

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors

(2011) Bin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Assessment of Myocardial Fibrosis With Cardiovascular Magnetic Resonance

(2011) Nathan Mewton et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Endothelial Cell–Derived Endothelin-1 Promotes Cardiac Fibrosis in Diabetic Hearts Through Stimulation of Endothelial-to-Mesenchymal Transition

(2010) Bambang Widyantoro et al.   CIRCULATION

Origins of Cardiac Fibroblasts

(2010) Elisabeth M. Zeisberg et al.   CIRCULATION RESEARCH

Hemocyte-Secreted Type IV Collagen Enhances BMP Signaling to Guide Renal Tubule Morphogenesis in Drosophila

(2010) Stephanie Bunt et al.   DEVELOPMENTAL CELL

Characterisation of the Drosophila procollagen lysyl hydroxylase, dPlod

(2010) Stephanie Bunt et al.   GENE EXPRESSION PATTERNS

Independent and additive prognostic ability of serum carboxy-terminal telopeptide of collagen type-I in heart failure patients: a multi-marker approach with high-negative predictive value to rule out long-term adverse events

(2010) D. N. Tziakas et al.   European Journal of Preventive Cardiology

The Collagen Receptor DDR2 Is Expressed During Early Cardiac Development

(2009) Edie C. Goldsmith et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Origin of Cardiac Fibroblasts and the Role of Periostin

(2009) Paige Snider et al.   CIRCULATION RESEARCH

Cardiac fibroblasts: At the heart of myocardial remodeling

(2009) Karen E. Porter et al.   PHARMACOLOGY & THERAPEUTICS

Periostin Is Required for Maturation and Extracellular Matrix Stabilization of Noncardiomyocyte Lineages of the Heart

(2008) Paige Snider et al.   CIRCULATION RESEARCH

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart

(2008) Bin Zhou et al.   NATURE

A myocardial lineage derives from Tbx18 epicardial cells

(2008) Chen-Leng Cai et al.   NATURE