How do Uremic Toxins Affect the Endothelium?

P-Cresylsulfate, the Protein-Bound Uremic Toxin, Increased Endothelial Permeability Partly Mediated by Src-Induced Phosphorylation of VE-Cadherin

(2020) Shih-Chieh Chen et al.   Toxins

The Impact of Diabetic Conditions and AGE/RAGE Signaling on Cardiac Fibroblast Migration

(2020) Stephanie D. Burr et al.   Frontiers in Cell and Developmental Biology

Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form

(2020) Anatoly A. Soshilov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aryl Hydrocarbon Receptor Activation and Tissue Factor Induction by Fluid Shear Stress and Indoxyl Sulfate in Endothelial Cells

(2020) Guillaume Lano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TRPV1: Structure, Endogenous Agonists, and Mechanisms

(2020) Miguel Benítez-Angeles et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protein-Bound Uremic Toxins in Hemodialysis Patients Relate to Residual Kidney Function, Are Not Influenced by Convective Transport, and Do Not Relate to Outcome

(2020) Maaike K. van Gelder et al.   Toxins

Crotonaldehyde-induced vascular relaxation and toxicity: Role of endothelium and transient receptor potential ankyrin-1 (TRPA1)

(2020) L. Jin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Endothelium structure and function in kidney health and disease

(2019) Noemie Jourde-Chiche et al.   Nature Reviews Nephrology

Increased concentrations of platelet- and endothelial-derived microparticles in patients with myocardial infarction and reduced renal function- a descriptive study

(2019) Josefin Mörtberg et al.   BMC Nephrology

Glycine Suppresses AGE/RAGE Signaling Pathway and Subsequent Oxidative Stress by Restoring Glo1 Function in the Aorta of Diabetic Rats and in HUVECs

(2019) Ziwei Wang et al.   Oxidative Medicine and Cellular Longevity

Receptor for advanced glycation end products: a key molecule in the genesis of chronic kidney disease vascular calcification and a potential modulator of sodium phosphate co-transporter PIT-1 expression

(2019) Karim Belmokhtar et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Removal of Protein-Bound Uremic Toxins during Hemodialysis Using a Binding Competitor

(2019) Magdalena Madero et al.   Clinical Journal of the American Society of Nephrology

Dual inhibition of endothelial miR-92a-3p and miR-489-3p reduces renal injury-associated atherosclerosis

(2019) Carrie B. Wiese et al.   ATHEROSCLEROSIS

Indoxyl Sulfate-Induced Extracellular Vesicles Released from Endothelial Cells Stimulate Vascular Smooth Muscle Cell Proliferation by Inducing Transforming Growth Factor-Beta Production

(2019) Jung-Hwa Ryu et al.   JOURNAL OF VASCULAR RESEARCH

Endothelial cell barriers: Transport of molecules between blood and tissues

(2019) Samaneh Yazdani et al.   TRAFFIC

Endothelial Microparticles in Uremia: Biomarkers and Potential Therapeutic Targets

(2019) Giane Favretto et al.   Toxins

Inhibition of miR-223 expression using a sponge strategy decreases restenosis in rat injured carotids

(2019) Eleonore M’baya-Moutoula et al.   Current Vascular Pharmacology

Uremic Serum Induces Inflammation in Cultured Human Endothelial Cells and Triggers Vascular Repair Mechanisms

(2019) Asmahan Eloueyk et al.   INFLAMMATION

Remote sensing and signaling in kidney proximal tubules stimulates gut microbiome-derived organic anion secretion

(2019) Jitske Jansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Bifunctional Adsorber Particle for the Removal of Hydrophobic Uremic Toxins from Whole Blood of Renal Failure Patients

(2019) Marieke Sternkopf et al.   Toxins

Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study

(2019) Remy J. H. Martens et al.   PLoS One

Spironolactone ameliorates endothelial dysfunction through inhibition of the AGE/RAGE axis in a chronic renal failure rat model

(2019) Chun-Cheng Wang et al.   BMC Nephrology

Indoxyl Sulfate Stimulates Angiogenesis by Regulating Reactive Oxygen Species Production via CYP1B1

(2019) Pei et al.   Toxins

Role of Resveratrol on Indoxyl Sulfate-Induced Endothelial Hyperpermeability via Aryl Hydrocarbon Receptor (AHR)/Src-Dependent Pathway

(2019) Eskedar Getachew Assefa et al.   Oxidative Medicine and Cellular Longevity

Association between Serum Indoxyl Sulfate Levels and Endothelial Function in Non-Dialysis Chronic Kidney Disease

(2019) Chih-Hsien Wang et al.   Toxins

MicroRNA-214 targets COX-2 to antagonize indoxyl sulfate (IS)-induced endothelial cell apoptosis

(2019) Shuzhen Li et al.   APOPTOSIS

Uremic toxins promote accumulation of oxidized protein and increased sensitivity to hydrogen peroxide in endothelial cells by impairing the autophagic flux

(2019) Silvia D. Rodrigues et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Uremic Toxin–Targeting as a Therapeutic Strategy for Preventing Cardiorenal Syndrome

(2019) Kensei Taguchi et al.   CIRCULATION JOURNAL

Tissue Factor

(2018) Steven P. Grover et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Increased circulating trimethylamine N-oxide contributes to endothelial dysfunction in a rat model of chronic kidney disease

(2018) Tiejun Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intestinal secretion of indoxyl sulfate as a possible compensatory excretion pathway in chronic kidney disease

(2018) Kaori Morimoto et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Protein-bounded uremic toxin p-cresylsulfate induces vascular permeability alternations

(2018) Wei-Hua Tang et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans

(2018) Vijaya B. Kolachalama et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Advanced glycation end products in the pathogenesis of chronic kidney disease

(2018) Naila Rabbani et al.   KIDNEY INTERNATIONAL

Aryl hydrocarbon receptor is activated in patients and mice with chronic kidney disease

(2018) Laetitia Dou et al.   KIDNEY INTERNATIONAL

Effect of prebiotic (fructooligosaccharide) on uremic toxins of chronic kidney disease patients: a randomized controlled trial

(2018) Christiane Ishikawa Ramos et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Stabilization of cell–cell junctions by active vitamin D ameliorates uraemia-induced loss of human endothelial barrier function

(2018) Marc Vila Cuenca et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Defective Autophagy in Atherosclerosis: To Die or to Senesce?

(2018) Mandy O. J. Grootaert et al.   Oxidative Medicine and Cellular Longevity

Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases

(2018) Maria Angela Incalza et al.   VASCULAR PHARMACOLOGY

Biochemical and Clinical Impact of Organic Uremic Retention Solutes: A Comprehensive Update

(2018) Raymond Vanholder et al.   Toxins

Uremic Advanced Glycation End Products and Protein‐Bound Solutes Induce Endothelial Dysfunction Through Suppression of Krüppel‐Like Factor 2

(2018) Keith Saum et al.   Journal of the American Heart Association

Endothelial Microparticles and Systemic Complement Activation in Patients With Chronic Kidney Disease

(2018) Diana Jalal et al.   Journal of the American Heart Association

The uremic toxin hippurate promotes endothelial dysfunction via the activation of Drp1-mediated mitochondrial fission

(2018) Mengjie Huang et al.   Redox Biology

Indoxyl glucuronide, a protein-bound uremic toxin, inhibits hypoxia-inducible factor‒dependent erythropoietin expression through activation of aryl hydrocarbon receptor

(2018) Hirobumi Asai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Indoxyl Sulfate Generates Free Radicals, Decreases Antioxidant Defense, and Leads to Damage to Mononuclear Blood Cells

(2018) Anna Pieniazek et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Impact of Uremic Toxicity Induced Inflammatory Response on the Cardiovascular Burden in Chronic Kidney Disease

(2018) Ligia Claro et al.   Toxins

Vitamin D Attenuates Endothelial Dysfunction in Uremic Rats and Maintains Human Endothelial Stability

(2018) Marc Vila Cuenca et al.   Journal of the American Heart Association

Mechanisms of tissue factor induction by the uremic toxin indole-3 acetic acid through aryl hydrocarbon receptor/nuclear factor-kappa B signaling pathway in human endothelial cells

(2018) Tawfik Addi et al.   ARCHIVES OF TOXICOLOGY

MicroRNA-142-3p improves vascular relaxation in uremia

(2018) Máté Kétszeri et al.   ATHEROSCLEROSIS

Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling

(2018) Toshiaki Nakano et al.   CIRCULATION

Effects of Uremic Serum Residue on OATP1B1- and OATP1B3-Mediated Pravastatin Uptake in OATP-Expressing HEK293 Cells and Human Hepatocytes

(2018) Hitoshi Uchiyama et al.   THERAPEUTIC APHERESIS AND DIALYSIS

Uremia Impacts VE-Cadherin and ZO-1 Expression in Human Endothelial Cell-to-Cell Junctions

(2018) Rayana Maciel et al.   Toxins

Indoxyl Sulfate Promotes Arterial Thrombosis in Rat Model via Increased Levels of Complex TF/VII, PAI-1, Platelet Activation as Well as Decreased Contents of SIRT1 and SIRT3

(2018) Malgorzata Karbowska et al.   Frontiers in Physiology

Association between uremic toxin-anthranilic acid and fibrinolytic system activity in predialysis patients at different stages of chronic kidney disease

(2017) Tomasz W. Kaminski et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

MicroRNA-92a Mediates Endothelial Dysfunction in CKD

(2017) Fenqing Shang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Role of Organic Anion Transporters in the Uptake of Protein-Bound Uremic Toxins by Human Endothelial Cells and Monocyte Chemoattractant Protein-1 Expression

(2017) Giane Favretto et al.   JOURNAL OF VASCULAR RESEARCH

Chronic kidney disease is associated with increased risk of venous thromboembolism recurrence

(2017) Marcello Rattazzi et al.   THROMBOSIS RESEARCH

Indoxyl sulfate – the uremic toxin linking hemostatic system disturbances with the prevalence of cardiovascular disease in patients with chronic kidney disease

(2017) Tomasz W. Kamiński et al.   BMC Nephrology

Blood coagulation system in patients with chronic kidney disease: a prospective observational study

(2017) Meng-Jie Huang et al.   BMJ Open

The Uremic Toxin Indoxyl Sulfate Accelerates Thrombotic Response after Vascular Injury in Animal Models

(2017) Malgorzata Karbowska et al.   Toxins

Uric Acid Induces Endothelial Dysfunction by Activating the HMGB1/RAGE Signaling Pathway

(2017) Wei Cai et al.   Biomed Research International

The effects of indoxyl sulfate-induced endothelial microparticles on neointimal hyperplasia formation in an ex vivo model

(2017) Jung-Hwa Ryu et al.   Annals of Surgical Treatment and Research

Microvesicles Derived from Indoxyl Sulfate Treated Endothelial Cells Induce Endothelial Progenitor Cells Dysfunction

(2017) Andres Carmona et al.   Frontiers in Physiology

Indoxyl sulfate (IS)-mediated immune dysfunction provokes endothelial damage in patients with end-stage renal disease (ESRD)

(2017) Hee Young Kim et al.   Scientific Reports

Mechanisms of MicroRNAs in Atherosclerosis

(2016) Andreas Schober et al.   Annual Review of Pathology-Mechanisms of Disease

The type III transporters (PiT-1 and PiT-2) are the major sodium-dependent phosphate transporters in the mice and human brains

(2016) Masatoshi Inden et al.   BRAIN RESEARCH

Synbiotics Easing Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial

(2016) M. Rossi et al.   Clinical Journal of the American Society of Nephrology

Reduced protein bound uraemic toxins in vegetarian kidney failure patients treated by haemodiafiltration

(2016) Sakina Kandouz et al.   Hemodialysis International

Crucial Role of the Aryl Hydrocarbon Receptor (AhR) in Indoxyl Sulfate-Induced Vascular Inflammation

(2016) Shunsuke Ito et al.   Journal of Atherosclerosis and Thrombosis

Indoxyl Sulfate Impairs Endothelial Progenitor Cells and Might Contribute to Vascular Dysfunction in Patients with Chronic Kidney Disease

(2016) Cheng-Jui Lin et al.   KIDNEY & BLOOD PRESSURE RESEARCH

p-Cresyl sulfate is associated with carotid arteriosclerosis in hemodialysis patients and promotes atherogenesis in apoE−/− mice

(2016) Ya J. Jing et al.   KIDNEY INTERNATIONAL

Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway

(2016) Kathryn K. Stevens et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Role of AGE/RAGE Signaling in Diabetes-Mediated Vascular Calcification

(2016) Amber M. Kay et al.   Journal of Diabetes Research

Paricalcitol, Microvascular and Endothelial Function in Non-Diabetic Chronic Kidney Disease: A Randomized Trial

(2015) Kristina Lundwall et al.   AMERICAN JOURNAL OF NEPHROLOGY

Indoxyl sulfate enhances IL-1β-induced E-selectin expression in endothelial cells in acute kidney injury by the ROS/MAPKs/NFκB/AP-1 pathway

(2015) Wen-Ching Shen et al.   ARCHIVES OF TOXICOLOGY

Deleterious vascular effects of indoxyl sulfate and reversal by oral adsorbent AST-120

(2015) Isabelle Six et al.   ATHEROSCLEROSIS

Two persistent organic pollutants which act through different xenosensors (alpha-endosulfan and 2,3,7,8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose metabolism

(2015) Ariane Ambolet-Camoit et al.   BIOCHIMIE

ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation

(2015) Olga Tornavaca et al.   JOURNAL OF CELL BIOLOGY

Hyperphosphatemia, Phosphoprotein Phosphatases, and Microparticle Release in Vascular Endothelial Cells

(2015) N. Abbasian et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Uremic Toxicity of Advanced Glycation End Products in CKD

(2015) A. E. M. Stinghen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia

(2015) S. Shivanna et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Indoxyl Sulfate, Not P-Cresyl Sulfate, is Associated with Advanced Glycation end Products in Patients on Long-Term Hemodialysis

(2015) Cheng-Jui Lin et al.   KIDNEY & BLOOD PRESSURE RESEARCH

The Organic Anion Transporter (OAT) Family: A Systems Biology Perspective

(2015) Sanjay K. Nigam et al.   PHYSIOLOGICAL REVIEWS

Thrombotic Role of Blood and Endothelial Cells in Uremia through Phosphatidylserine Exposure and Microparticle Release

(2015) Chunyan Gao et al.   PLoS One

Indoxyl Sulfate-Induced Oxidative Stress, Mitochondrial Dysfunction, and Impaired Biogenesis Are Partly Protected by Vitamin C and N-Acetylcysteine

(2015) Wen-Chin Lee et al.   TheScientificWorldJOURNAL

Effect of PKC-β Signaling Pathway on Expression of MCP-1 and VCAM-1 in Different Cell Models in Response to Advanced Glycation End Products (AGEs)

(2015) Lisienny Rempel et al.   Toxins

Indoxyl Sulfate-Induced Oxidative Stress, Mitochondrial Dysfunction, and Impaired Biogenesis Are Partly Protected by Vitamin C and N-Acetylcysteine

(2015) Wen-Chin Lee et al.   Scientific World Journal

Endothelial Barrier and Its Abnormalities in Cardiovascular Disease

(2015) Dimitry A. Chistiakov et al.   Frontiers in Physiology

Role of Flow-Sensitive microRNAs in Endothelial Dysfunction and Atherosclerosis

(2014) Sandeep Kumar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Toxicity of Phosphate in Chronic Kidney Disease

(2014) Priscilla Gross et al.   CIRCULATION JOURNAL

Effect of Increasing Dietary Fiber on Plasma Levels of Colon-Derived Solutes in Hemodialysis Patients

(2014) T. L. Sirich et al.   Clinical Journal of the American Society of Nephrology

Aryl Hydrocarbon Receptor Mediates Indoxyl Sulfate-Induced Cellular Senescence in Human Umbilical Vein Endothelial Cells

(2014) Masayuki Koizumi et al.   Journal of Atherosclerosis and Thrombosis

Protein-Bound Uremic Toxins Induce Tissue Remodeling by Targeting the EGF Receptor

(2014) C.-Y. Sun et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Cardiovascular Effect of the Uremic Solute Indole-3 Acetic Acid

(2014) L. Dou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Klotho Prevents NFκB Translocation and Protects Endothelial Cell From Senescence Induced by Uremia

(2014) Paula Buendía et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Prevalence of subclinical atheromatosis and associated risk factors in chronic kidney disease: the NEFRONA study

(2014) A. Betriu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Direct, Acute Effects of Klotho and FGF23 on Vascular Smooth Muscle and Endothelium

(2014) Isabelle Six et al.   PLoS One

Differential Effects of Indoxyl Sulfate and Inorganic Phosphate in a Murine Cerebral Endothelial Cell Line (bEnd.3)

(2014) Andréa Stinghen et al.   Toxins

Localization of type-III sodium-dependent phosphate transporter 2 in the mouse brain

(2013) Masatoshi Inden et al.   BRAIN RESEARCH

Effects of sevelamer treatment on cardiovascular abnormalities in mice with chronic renal failure

(2013) Julien Maizel et al.   KIDNEY INTERNATIONAL

Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway

(2013) Bertrand Gondouin et al.   KIDNEY INTERNATIONAL

The SLCO (former SLC21) superfamily of transporters

(2013) Bruno Hagenbuch et al.   MOLECULAR ASPECTS OF MEDICINE

Haemostasis in chronic kidney disease

(2013) Jens Lutz et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

High-efficiency on-line haemodiafiltration improves conduit artery endothelial function compared with high-flux haemodialysis in end-stage renal disease patients

(2013) J. Bellien et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

A Decreased Level of Serum Soluble Klotho Is an Independent Biomarker Associated with Arterial Stiffness in Patients with Chronic Kidney Disease

(2013) Masashi Kitagawa et al.   PLoS One

Effects of phosphate on vascular function under normal conditions and influence of the uraemic state

(2012) I. Six et al.   CARDIOVASCULAR RESEARCH

Activation of Aryl Hydrocarbon Receptor Mediates Indoxyl Sulfate-Induced Monocyte Chemoattractant Protein-1 Expression in Human Umbilical Vein Endothelial Cells

(2012) Ippei Watanabe et al.   CIRCULATION JOURNAL

Translational evidence that impaired autophagy contributes to arterial ageing

(2012) Thomas J. LaRocca et al.   JOURNAL OF PHYSIOLOGY-LONDON

Normal and Pathologic Concentrations of Uremic Toxins

(2012) F. Duranton et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibition of eNOS phosphorylation mediates endothelial dysfunction in renal failure: new effect of asymmetric dimethylarginine

(2012) Hidemi Kajimoto et al.   KIDNEY INTERNATIONAL

Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation

(2012) Chiao-Yin Sun et al.   KIDNEY INTERNATIONAL

High phosphate directly affects endothelial function by downregulating annexin II

(2012) Giovana Seno Di Marco et al.   KIDNEY INTERNATIONAL

Indoxyl sulfate enhances angiotensin II signaling through upregulation of epidermal growth factor receptor expression in vascular smooth muscle cells

(2012) Hidehisa Shimizu et al.   LIFE SCIENCES

Drug transport by Organic Anion Transporters (OATs)

(2012) Gerhard Burckhardt   PHARMACOLOGY & THERAPEUTICS

EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes

(2012) Sung Gu Han et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

In Vivo Vascular Wall Shear Rate and Circumferential Strain of Renal Disease Patients

(2012) Dae Woo Park et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

MAP Kinase Pathways

(2012) D. K. Morrison   Cold Spring Harbor Perspectives in Biology

Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo

(2012) Fabrizio Orsenigo et al.   Nature Communications

A Metabolomic Approach to Clarifying the Effect of AST-120 on 5/6 Nephrectomized Rats by Capillary Electrophoresis with Mass Spectrometry (CE-MS)

(2012) Yasutoshi Akiyama et al.   Toxins

Comparison of Calcium Acetate and Sevelamer on Vascular Function and Fibroblast Growth Factor 23 in CKD Patients: A Randomized Clinical Trial

(2011) Mahmut Ilker Yilmaz et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Nocturnal Hemodialysis Is Associated with Restoration of Early-Outgrowth Endothelial Progenitor-Like Cell Function

(2011) D. A. Yuen et al.   Clinical Journal of the American Society of Nephrology

Effects of indoxyl sulfate on adherens junctions of endothelial cells and the underlying signaling mechanism

(2011) Yu-Sen Peng et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Serum free p-cresyl sulfate levels predict cardiovascular and all-cause mortality in elderly hemodialysis patients--a prospective cohort study

(2011) I.-W. Wu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney

(2011) Y. Miyamoto et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Uremic Toxins Inhibit Transport by Breast Cancer Resistance Protein and Multidrug Resistance Protein 4 at Clinically Relevant Concentrations

(2011) Henricus A. M. Mutsaers et al.   PLoS One

Vascular Incompetence in Dialysis Patients-Protein-Bound Uremic Toxins and Endothelial Dysfunction

(2011) Noémie Jourde-Chiche et al.   SEMINARS IN DIALYSIS

Indoxyl Sulfate Upregulates Expression of ICAM-1 and MCP-1 by Oxidative Stress-Induced NF-ĸB Activation

(2010) Zohra Tumur et al.   AMERICAN JOURNAL OF NEPHROLOGY

Indoxyl Sulfate Stimulates Monocyte Chemoattractant Protein-1 Expression in Human Umbilical Vein Endothelial Cells by Inducing Oxidative Stress Through Activation of the NADPH Oxidase-Nuclear Factor-κB Pathway

(2010) Natsumi Masai et al.   CIRCULATION JOURNAL

Role of Residual Renal Function in Phosphate Control and Anemia Management in Chronic Hemodialysis Patients

(2010) E. L. Penne et al.   Clinical Journal of the American Society of Nephrology

Vegetarian Compared with Meat Dietary Protein Source and Phosphorus Homeostasis in Chronic Kidney Disease

(2010) S. M. Moe et al.   Clinical Journal of the American Society of Nephrology

Indoxyl Sulfate-Induced Endothelial Dysfunction in Patients with Chronic Kidney Disease via an Induction of Oxidative Stress

(2010) M. Yu et al.   Clinical Journal of the American Society of Nephrology

Indoxyl Sulfate Induces Leukocyte-Endothelial Interactions through Up-regulation of E-selectin

(2010) Shunsuke Ito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progenitor cells and vascular function are impaired in patients with chronic kidney disease

(2010) Kim E. Jie et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Chronic kidney disease and venous thromboembolism: a prospective study

(2010) A. R. Folsom et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Uremic Retention Solute p-Cresyl Sulfate and Markers of Endothelial Damage

(2009) Björn K.I. Meijers et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Indoxyl Sulfate Inhibits Nitric Oxide Production and Cell Viability by Inducing Oxidative Stress in Vascular Endothelial Cells

(2009) Zohra Tumur et al.   AMERICAN JOURNAL OF NEPHROLOGY

The Role of Endothelial Progenitor Cells in Acute Kidney Injury

(2009) Francesca Becherucci et al.   BLOOD PURIFICATION

AMP-Activated Protein Kinase Functionally Phosphorylates Endothelial Nitric Oxide Synthase Ser633

(2009) Zhen Chen et al.   CIRCULATION RESEARCH

Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients

(2009) F. C. Barreto et al.   Clinical Journal of the American Society of Nephrology

Nitric oxide inhibits von Willebrand factor-mediated platelet adhesion and spreading through regulation of integrin αIIbβ3and myosin light chain

(2009) W. ROBERTS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Levels of circulating endothelial progenitor cells are related to uremic toxins and vascular injury in hemodialysis patients

(2009) N JOURDE-CHICHE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Free p-cresylsulphate is a predictor of mortality in patients at different stages of chronic kidney disease

(2009) S. Liabeuf et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

p-Cresyl sulfate serum concentrations in haemodialysis patients are reduced by the prebiotic oligofructose-enriched inulin

(2009) B. K. I. Meijers et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Protein-bound uraemic toxin removal in haemodialysis and post-dilution haemodiafiltration

(2009) D. H. Krieter et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Increased Plasma and Endothelial Cell Expression of Chemokines and Adhesion Molecules in Chronic Kidney Disease

(2009) A.E.M. Stinghen et al.   NEPHRON CLINICAL PRACTICE

p38MAPK: stress responses from molecular mechanisms to therapeutics

(2009) Lydia R. Coulthard et al.   TRENDS IN MOLECULAR MEDICINE

AGE/RAGE produces endothelial dysfunction in coronary arterioles in Type 2 diabetic mice

(2008) Xue Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vitamin D and Kidney Disease

(2008) W. Al-Badr et al.   Clinical Journal of the American Society of Nephrology

Effective removal of protein-bound uraemic solutes by different convective strategies: a prospective trial

(2008) N. Meert et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Serum  2-microglobulin level is a significant predictor of mortality in maintenance haemodialysis patients

(2008) S. Okuno et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Short-Term Treatment with Sevelamer Increases Serum Fetuin-A Concentration and Improves Endothelial Dysfunction in Chronic Kidney Disease Stage 4 Patients

(2007) K. Caglar et al.   Clinical Journal of the American Society of Nephrology

Chronic Kidney Disease Increases Risk for Venous Thromboembolism

(2007) K. Wattanakit et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY