Indoxyl sulfate – the uremic toxin linking hemostatic system disturbances with the prevalence of cardiovascular disease in patients with chronic kidney disease

Moderate Increase of Indoxyl Sulfate Promotes Monocyte Transition into Profibrotic Macrophages

(2016) Chiara Barisione et al.   PLoS One

Indoxyl Sulfate: A Candidate Target for the Prevention and Treatment of Cardiovascular Disease in Chronic Kidney Disease

(2015) Chiara Barisione et al.   CURRENT DRUG TARGETS

Tryptophan-kynurenine pathway is dysregulated in inflammation and immune activation

(2015) Ming-Hui Zou   Frontiers in Bioscience-Landmark

The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia

(2015) S. Shivanna et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Soluble urokinase receptor is a biomarker of cardiovascular disease in chronic kidney disease

(2015) Björn Meijers et al.   KIDNEY INTERNATIONAL

Uremic Retention Solute Indoxyl Sulfate Level Is Associated with Prolonged QTc Interval in Early CKD Patients

(2015) Wei-Hua Tang et al.   PLoS One

Meta-Analysis of the Associations of p-Cresyl Sulfate (PCS) and Indoxyl Sulfate (IS) with Cardiovascular Events and All-Cause Mortality in Patients with Chronic Renal Failure

(2015) Cheng-Jui Lin et al.   PLoS One

Interrelationship of Multiple Endothelial Dysfunction Biomarkers with Chronic Kidney Disease

(2015) Jing Chen et al.   PLoS One

Cardiorenal syndrome: acute kidney injury secondary to cardiovascular disease and role of protein-bound uraemic toxins

(2014) Suree Lekawanvijit et al.   JOURNAL OF PHYSIOLOGY-LONDON

Kidney disease and risk of venous thromboembolism: a nationwide population-based case-control study

(2014) C. F. Christiansen et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Prognostic Value of Serum Von Willebrand Factor, but Not Soluble ICAM and VCAM, for Mortality and Cardiovascular Events is Independent of Residual Renal Function in Peritoneal Dialysis Patients

(2014) J. Dong et al.   PERITONEAL DIALYSIS INTERNATIONAL

Indoxyl Sulfate Downregulates Expression of Mas Receptor via OAT3/AhR/Stat3 Pathway in Proximal Tubular Cells

(2014) Hwee-Yeong Ng et al.   PLoS One

Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment

(2014)   Lancet Diabetes & Endocrinology

Reduction of indoxyl sulfate by AST-120 attenuates monocyte inflammation related to chronic kidney disease

(2013) Shunsuke Ito et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway

(2013) Bertrand Gondouin et al.   KIDNEY INTERNATIONAL

Haemostasis in chronic kidney disease

(2013) Jens Lutz et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Optimized Metabolomic Approach to Identify Uremic Solutes in Plasma of Stage 3–4 Chronic Kidney Disease Patients

(2013) Henricus A. M. Mutsaers et al.   PLoS One

The role of protein-bound uremic toxins on peripheral artery disease and vascular access failure in patients on hemodialysis

(2012) Cheng-Jui Lin et al.   ATHEROSCLEROSIS

Uremic Serum and Solutes Increase Post–Vascular Interventional Thrombotic Risk Through Altered Stability of Smooth Muscle Cell Tissue Factor

(2012) Vipul C. Chitalia et al.   CIRCULATION

Cardiorenal Syndrome

(2012) Suree Lekawanvijit et al.   CIRCULATION RESEARCH

HPLC-Fluorescence Method for Measurement of the Uremic Toxin Indoxyl Sulfate in Plasma

(2012) M. Al Za'abi et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Inflammatory activation: cardiac, renal, and cardio-renal interactions in patients with the cardiorenal syndrome

(2011) Paolo C. Colombo et al.   HEART FAILURE REVIEWS

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Kynurenine pathway – a new link between endothelial dysfunction and carotid atherosclerosis in chronic kidney disease patients

(2010) K Pawlak et al.   Advances in Medical Sciences

Indoxyl Sulfate Upregulates Expression of ICAM-1 and MCP-1 by Oxidative Stress-Induced NF-ĸB Activation

(2010) Zohra Tumur et al.   AMERICAN JOURNAL OF NEPHROLOGY

Indoxyl Sulfate Stimulates Monocyte Chemoattractant Protein-1 Expression in Human Umbilical Vein Endothelial Cells by Inducing Oxidative Stress Through Activation of the NADPH Oxidase-Nuclear Factor-κB Pathway

(2010) Natsumi Masai et al.   CIRCULATION JOURNAL

Circulating soluble urokinase plasminogen activator receptor predicts cancer, cardiovascular disease, diabetes and mortality in the general population

(2010) J. Eugen-Olsen et al.   JOURNAL OF INTERNAL MEDICINE

Hyperfibrinolysis, uPA/suPAR System, Kynurenines, and the Prevalence of Cardiovascular Disease in Patients With Chronic Renal Failure on Conservative Treatment

(2009) Krystyna Pawlak et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Enhanced levels of urokinase plasminogen activator and its soluble receptor in common variable immunodeficiency

(2009) Børre Fevang et al.   CLINICAL IMMUNOLOGY

Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients

(2009) F. C. Barreto et al.   Clinical Journal of the American Society of Nephrology

Increased Plasma and Endothelial Cell Expression of Chemokines and Adhesion Molecules in Chronic Kidney Disease

(2009) A.E.M. Stinghen et al.   NEPHRON CLINICAL PRACTICE

Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-κB activation in endothelial cells

(2008) Su-Ryun Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Chronic Kidney Disease and Its Complications

(2008) Robert Thomas et al.   PRIMARY CARE

Relations between Concentrations of Asymmetric Dimethylarginine and Neopterin as Potential Risk Factors for Cardiovascular Diseases in Haemodialysis-Treated Patients

(2008) Emre Avcı et al.   RENAL FAILURE