Review on Toll-Like Receptor Activation in Myasthenia Gravis: Application to the Development of New Experimental Models

Increased expression of Toll-like receptors 7 and 9 in myasthenia gravis thymus characterized by active Epstein–Barr virus infection

(2016) Paola Cavalcante et al.   IMMUNOBIOLOGY

Toll-Like Receptor 11 (TLR11) Interacts with Flagellin and Profilin through Disparate Mechanisms

(2016) Hirotsugu Hatai et al.   PLoS One

Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis

(2015) Reza Khorooshi et al.   ACTA NEUROPATHOLOGICA

Toll-Like Receptor Pathways in Autoimmune Diseases

(2015) Ji-Qing Chen et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Space and time: New considerations about the relationship between Toll-like receptors (TLRs) and type I interferons (IFNs)

(2015) Darren J. Perkins et al.   CYTOKINE

IL-17-producing CD4+T cells contribute to the loss of B-cell tolerance in experimental autoimmune myasthenia gravis

(2015) Hanne Schaffert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Guidelines for standard preclinical experiments in the mouse model of myasthenia gravis induced by acetylcholine receptor immunization

(2015) Erdem Tuzun et al.   EXPERIMENTAL NEUROLOGY

Standardization of the experimental autoimmune myasthenia gravis (EAMG) model by immunization of rats with Torpedo californica acetylcholine receptors — Recommendations for methods and experimental designs

(2015) Mario Losen et al.   EXPERIMENTAL NEUROLOGY

Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases

(2015) Atsuo Kanno et al.   Nature Communications

Beyond dsRNA: Toll-like receptor 3 signalling in RNA-induced immune responses

(2014) Megumi Tatematsu et al.   BIOCHEMICAL JOURNAL

In vivoAdministration of TLR9 Agonist Reduces the Severity of Experimental Autoimmune Encephalomyelitis. The Role of Plasmacytoid Dendritic Cells and B Lymphocytes

(2014) Ana Leda F. Longhini et al.   CNS Neuroscience & Therapeutics

Thymoma-associated myasthenia gravis: On the search for a pathogen signature

(2014) Perrine Cufi et al.   JOURNAL OF AUTOIMMUNITY

Innate immunity in myasthenia gravis thymus: Pathogenic effects of Toll-like receptor 4 signaling on autoimmunity

(2014) Chiara Cordiglieri et al.   JOURNAL OF AUTOIMMUNITY

Experimental Autoimmune Myasthenia Gravis (EAMG): From immunochemical characterization to therapeutic approaches

(2014) Sara Fuchs et al.   JOURNAL OF AUTOIMMUNITY

TLR9 expressed on plasma membrane acts as a negative regulator of human B cell response

(2014) Thomas Guerrier et al.   JOURNAL OF AUTOIMMUNITY

Central role of interferon-beta in thymic events leading to myasthenia gravis

(2014) Perrine Cufi et al.   JOURNAL OF AUTOIMMUNITY

Myasthenia gravis: A comprehensive review of immune dysregulation and etiological mechanisms

(2014) Sonia Berrih-Aknin et al.   JOURNAL OF AUTOIMMUNITY

A Role for the Adaptor Proteins TRAM and TRIF in Toll-like Receptor 2 Signaling

(2014) Nadra J. Nilsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lymphatic vessels and tertiary lymphoid organs

(2014) Nancy H. Ruddle   JOURNAL OF CLINICAL INVESTIGATION

Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection

(2014) S. M. Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensing the enemy within: how macrophages detect intracellular Gram-negative bacteria

(2014) Dieter Demon et al.   TRENDS IN BIOCHEMICAL SCIENCES

Toll-Like Receptor Signaling Pathways

(2014) Takumi Kawasaki et al.   Frontiers in Immunology

Molecular and Cellular Regulation of Toll-Like Receptor-4 Activity Induced by Lipopolysaccharide Ligands

(2014) Ardiyanto Liaunardy-Jopeace et al.   Frontiers in Immunology

TLR2 and TLR4 in Autoimmune Diseases: a Comprehensive Review

(2013) Yu Liu et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

RNA recognition by human TLR8 can lead to autoimmune inflammation

(2013) Cristiana Guiducci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors

(2013) Jeroen van Bergenhenegouwen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Expression of Immune Molecules CD25 and CXCL13 Correlated with Clinical Severity of Myasthenia Gravis

(2013) Min Zhang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Altered expression of miR-146a in myasthenia gravis

(2013) Jiayin Lu et al.   NEUROSCIENCE LETTERS

The thymus in autoimmune Myasthenia Gravis: Paradigm for a tertiary lymphoid organ

(2013) J.-M. Weiss et al.   REVUE NEUROLOGIQUE

High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9–TRIF pathway

(2013) Claudia Volpi et al.   Nature Communications

Implication of double-stranded RNA signaling in the etiology of autoimmune myasthenia gravis

(2012) Perrine Cufi et al.   ANNALS OF NEUROLOGY

SDF-1/CXCL12 recruits B cells and antigen-presenting cells to the thymus of autoimmune myasthenia gravis patients

(2012) Julia Miriam Weiss et al.   IMMUNOBIOLOGY

Possible Involvement of Toll-Like Receptors in the Pathogenesis of Myasthenia Gravis

(2012) Yu-Zhong Wang et al.   INFLAMMATION

The Role of UNC93B1 Protein in Surface Localization of TLR3 Receptor and in Cell Priming to Nucleic Acid Agonists

(2012) Jelka Pohar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD4 costimulation is not required in a novel LPS-enhanced model of myasthenia gravis

(2012) Windy Allman et al.   JOURNAL OF NEUROIMMUNOLOGY

Thymic epithelial cells: working class heroes for T cell development and repertoire selection

(2012) Graham Anderson et al.   TRENDS IN IMMUNOLOGY

The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis

(2011) Y. M. Ambrosini et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Toll-like receptor 3 ligand polyinosinic:polycytidylic acid enhances autoimmune disease in a retinal autoimmunity model

(2011) Xiangrong Ren et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren’s syndrome-like disease

(2011) S-R Nandula et al.   ORAL DISEASES

Activation of the Alternative NFκB Pathway Improves Disease Symptoms in a Model of Sjogren's Syndrome

(2011) Adi Gilboa-Geffen et al.   PLoS One

UNC93B1 Physically Associates with Human TLR8 and Regulates TLR8-Mediated Signaling

(2011) Hiroki Itoh et al.   PLoS One

Toll-like receptor driven B cell activation in the induction of systemic autoimmunity

(2011) Nathaniel M. Green et al.   SEMINARS IN IMMUNOLOGY

Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis

(2010) Osamu Higuchi et al.   ANNALS OF NEUROLOGY

Innate pathways to B-cell activation and tolerance

(2010) Steve P. Crampton et al.   Annals of the New York Academy of Sciences

Epstein-Barr virus promotes interferon-α production by plasmacytoid dendritic cells

(2010) Timothy E. Quan et al.   ARTHRITIS AND RHEUMATISM

Thymic remodeling associated with hyperplasia in myasthenia gravis

(2010) Rozen Le Panse et al.   AUTOIMMUNITY

The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update

(2010) H. Okada et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Targeting the TLR9–MyD88 pathway in the regulation of adaptive immune responses

(2010) Xiaopei Huang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Use of defined TLR ligands as adjuvants within human vaccines

(2010) Malcolm S. Duthie et al.   IMMUNOLOGICAL REVIEWS

TRIF Mediates Toll-like Receptor 5-induced Signaling in Intestinal Epithelial Cells

(2010) Yoon Jeong Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ectopic and high CXCL13 chemokine expression in myasthenia gravis with thymic lymphoid hyperplasia

(2010) Yu-Ming Shiao et al.   JOURNAL OF NEUROIMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Detection of poliovirus-infected macrophages in thymus of patients with myasthenia gravis

(2010) P. Cavalcante et al.   NEUROLOGY

Analysis of Humoral Immune Response in Experimental Autoimmune Pancreatitis in Mice

(2010) Masanori Asada et al.   PANCREAS

Experimental autoimmune encephalomyelitis as a testing paradigm for adjuvants and vaccines

(2010) Jane E. Libbey et al.   VACCINE

Role of Regulatory T Cells in a New Mouse Model of Experimental Autoimmune Myositis

(2009) Yves Allenbach et al.   AMERICAN JOURNAL OF PATHOLOGY

Experimental Autoimmune Vasculitis

(2009) Mark A. Little et al.   AMERICAN JOURNAL OF PATHOLOGY

CCL21 overexpressed on lymphatic vessels drives thymic hyperplasia in myasthenia

(2009) Sonia Berrih-Aknin et al.   ANNALS OF NEUROLOGY

Epstein-Barr virus (EBV)–encoded small RNA is released from EBV-infected cells and activates signaling from toll-like receptor 3

(2009) Dai Iwakiri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IDO Mediates TLR9-Driven Protection from Experimental Autoimmune Diabetes

(2009) F. Fallarino et al.   JOURNAL OF IMMUNOLOGY

Interferon alpha and neuromuscular disorders

(2009) Joerg-Patrick Stübgen   JOURNAL OF NEUROIMMUNOLOGY

Regulatory and Pathogenic Mechanisms in Human Autoimmune Myasthenia Gravis

(2008) Rozen Le Panse et al.   Annals of the New York Academy of Sciences

B cell autonomous TLR signaling and autoimmunity

(2008) Almut Meyer-Bahlburg et al.   AUTOIMMUNITY REVIEWS

The Adjuvant Effect in Infection and Autoimmunity

(2008) Noel R. Rose   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

A comparison of long-term post-thymectomy outcome of anti-AChR-positive, anti-AChR-negative and anti-MuSK-positive patients with non-thymomatous myasthenia gravis

(2008) José M Ponseti et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Autoantibodies against Type I Interferons as an Additional Diagnostic Criterion for Autoimmune Polyendocrine Syndrome Type I

(2008) Antonella Meloni et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

(2008) Mirjam Kool et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toll-like receptors and autoimmunity

(2007) Julia Hurst et al.   AUTOIMMUNITY REVIEWS