Depression with atypical neurovegetative symptoms shares genetic predisposition with immuno-metabolic traits and alcohol consumption

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

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Data-driven biological subtypes of depression: systematic review of biological approaches to depression subtyping

(2019) Lian Beijers et al.   MOLECULAR PSYCHIATRY

Characteristics, comorbidities, and correlates of atypical depression: evidence from the UK Biobank Mental Health Survey

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Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

(2019) Hunna J. Watson et al.   NATURE GENETICS

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

(2019) Henry R. Kranzler et al.   Nature Communications

PRSice-2: Polygenic Risk Score software for biobank-scale data

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Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Signatures of negative selection in the genetic architecture of human complex traits

(2018) Jian Zeng et al.   NATURE GENETICS

The Risk Factors of the Alcohol Use Disorders—Through Review of Its Comorbidities

(2018) Ping Yang et al.   Frontiers in Neuroscience

Prevalence of Depression in the Community from 30 Countries between 1994 and 2014

(2018) Grace Y. Lim et al.   Scientific Reports

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

(2018) Symen Ligthart et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

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The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

(2017) Helen R Warren et al.   NATURE GENETICS

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

(2017) Yuri Milaneschi et al.   JAMA Psychiatry

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

(2017) Allan M. Andersen et al.   JAMA Psychiatry

KLBis associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

(2016) Gunter Schumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

(2016) Tuomas O. Kilpeläinen et al.   Nature Communications

Depression is not a consistent syndrome: An investigation of unique symptom patterns in the STAR*D study

(2015) Eiko I. Fried et al.   JOURNAL OF AFFECTIVE DISORDERS

Atypical features in depression: Association with obesity and bipolar disorder

(2015) Dorota Łojko et al.   JOURNAL OF AFFECTIVE DISORDERS

Polygenic dissection of major depression clinical heterogeneity

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Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

PRSice: Polygenic Risk Score software

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PPAR-γ Agonism as a Modulator of Mood: Proof-of-Concept for Pioglitazone in Bipolar Depression

(2014) David E. Kemp et al.   CNS DRUGS

Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

(2014) Peter M. Visscher et al.   PLoS Genetics

Depression With Atypical Features and Increase in Obesity, Body Mass Index, Waist Circumference, and Fat Mass

(2014) Aurélie M. Lasserre et al.   JAMA Psychiatry

Leptin receptor deficiency confers resistance to behavioral effects of fluoxetine and desipramine via separable substrates

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The Epidemiology of Depression Across Cultures

(2013) Ronald C. Kessler et al.   Annual Review of Public Health

A Better Coefficient of Determination for Genetic Profile Analysis

(2012) Sang Hong Lee et al.   GENETIC EPIDEMIOLOGY

Estimating Missing Heritability for Disease from Genome-wide Association Studies

(2011) Sang Hong Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Epidemiology of Major Depression With Atypical Features

(2011) Carlos Blanco et al.   JOURNAL OF CLINICAL PSYCHIATRY

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

Disruption of hypothalamic leptin signaling in mice leads to early-onset obesity, but physiological adaptations in mature animals stabilize adiposity levels

(2010) Laurence E. Ring et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity and leptin resistance: distinguishing cause from effect

(2010) Martin G. Myers et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Prevalence and Correlates of Depression with Atypical Symptoms in Hong Kong

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