Disruption of hypothalamic leptin signaling in mice leads to early-onset obesity, but physiological adaptations in mature animals stabilize adiposity levels

Endogenous Leptin Signaling in the Caudal Nucleus Tractus Solitarius and Area Postrema Is Required for Energy Balance Regulation

(2010) Matthew R. Hayes et al.   Cell Metabolism

A Recurring Problem With the Analysis of Energy Expenditure in Genetic Models Expressing Lean and Obese Phenotypes

(2010) A. A. Butler et al.   DIABETES

Prevalence and Trends in Obesity Among US Adults, 1999-2008

(2010) Katherine M. Flegal   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

From observation to experimentation: leptin action in the mediobasal hypothalamus

(2009) Kevin W Williams et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Recent dynamics suggest selected countries catching up to US obesity

(2009) Barry M Popkin   AMERICAN JOURNAL OF CLINICAL NUTRITION

A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure

(2009) Vijay K. Yadav et al.   CELL

The Geometry of Leptin Action in the Brain: More Complicated Than a Simple ARC

(2009) Martin G. Myers et al.   Cell Metabolism

Leptin-Dependent Control of Glucose Balance and Locomotor Activity by POMC Neurons

(2009) Lihong Huo et al.   Cell Metabolism

Leptin Acts via Leptin Receptor-Expressing Lateral Hypothalamic Neurons to Modulate the Mesolimbic Dopamine System and Suppress Feeding

(2009) Gina M. Leinninger et al.   Cell Metabolism

PDK1 Deficiency in POMC-Expressing Cells Reveals FOXO1-Dependent and -Independent Pathways in Control of Energy Homeostasis and Stress Response

(2008) Bengt F. Belgardt et al.   Cell Metabolism

Hypothalamic ERK Mediates the Anorectic and Thermogenic Sympathetic Effects of Leptin

(2008) K. Rahmouni et al.   DIABETES

Dorsal Hindbrain 5′-Adenosine Monophosphate-Activated Protein Kinase as an Intracellular Mediator of Energy Balance

(2008) Matthew R. Hayes et al.   ENDOCRINOLOGY

Hindbrain Leptin Stimulation Induces Anorexia and Hyperthermia Mediated by Hindbrain Melanocortin Receptors

(2008) Karolina P. Skibicka et al.   ENDOCRINOLOGY

Fate mapping Nkx2.1-lineage cells in the mouse telencephalon

(2007) Qing Xu et al.   JOURNAL OF COMPARATIVE NEUROLOGY