Leptin receptor deficiency confers resistance to behavioral effects of fluoxetine and desipramine via separable substrates

Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels

(2012) Stefan Kloiber et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Selective deletion of leptin receptors in adult hippocampus induces depression-related behaviours

(2012) Ming Guo et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression

(2012) M Guo et al.   Translational Psychiatry

Leptin Does Not Directly Affect CNS Serotonin Neurons to Influence Appetite

(2011) Daniel D. Lam et al.   Cell Metabolism

Leptin levels are associated with decreased depressive symptoms in women across the weight spectrum, independent of body fat

(2011) Elizabeth A. Lawson et al.   CLINICAL ENDOCRINOLOGY

Impaired CNS Leptin Action Is Implicated in Depression Associated with Obesity

(2011) Nobuko Yamada et al.   ENDOCRINOLOGY

Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3β/β-catenin signaling

(2011) J C Garza et al.   MOLECULAR PSYCHIATRY

Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project

(2010) Rudolf Uher et al.   AMERICAN JOURNAL OF PSYCHIATRY

Overweight, Obesity, and Depression

(2010) Floriana S. Luppino et al.   ARCHIVES OF GENERAL PSYCHIATRY

Is Glycogen Synthase Kinase-3 a Central Modulator in Mood Regulation?

(2010) Xiaohua Li et al.   NEUROPSYCHOPHARMACOLOGY

Neurobehavioral deficits in db/db diabetic mice

(2010) Ajaykumar N. Sharma et al.   PHYSIOLOGY & BEHAVIOR

Leptin targets in the mouse brain

(2009) Michael M. Scott et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Acute administration of leptin produces anxiolytic-like effects: a comparison with fluoxetine

(2009) Jing Liu et al.   PSYCHOPHARMACOLOGY

Akt/GSK3 Signaling in the Action of Psychotropic Drugs

(2008) Jean-Martin Beaulieu et al.   Annual Review of Pharmacology and Toxicology