Structural insight into the role of novel SARS-CoV-2 E protein: A potential target for vaccine development and other therapeutic strategies

Molecular Evolutionary Genetics Analysis (MEGA) for macOS

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A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Responding to Covid-19 — A Once-in-a-Century Pandemic?

(2020) Bill Gates   NEW ENGLAND JOURNAL OF MEDICINE

Coronavirus envelope protein: current knowledge

(2019) Dewald Schoeman et al.   Virology Journal

Structural model of the SARS coronavirus E channel in LMPG micelles

(2018) Wahyu Surya et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

CASTp 3.0: computed atlas of surface topography of proteins

(2018) Wei Tian et al.   NUCLEIC ACIDS RESEARCH

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Clustal Omega for making accurate alignments of many protein sequences

(2017) Fabian Sievers et al.   PROTEIN SCIENCE

MolProbity: More and better reference data for improved all-atom structure validation

(2017) Christopher J. Williams et al.   PROTEIN SCIENCE

STRUM: structure-based prediction of protein stability changes upon single-point mutation

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Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses

(2016) Shuo Su et al.   TRENDS IN MICROBIOLOGY

MMB-GUI: a fast morphing method demonstrates a possible ribosomal tRNA translocation trajectory

(2015) Alex Tek et al.   NUCLEIC ACIDS RESEARCH

Coronavirus envelope (E) protein remains at the site of assembly

(2015) Pavithra Venkatagopalan et al.   VIROLOGY

Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine

(2015) Jose M. Jimenez-Guardeño et al.   PLoS Pathogens

Structure of a Conserved Golgi Complex-targeting Signal in Coronavirus Envelope Proteins

(2014) Yan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM-GUIMembrane Buildertoward realistic biological membrane simulations

(2014) Emilia L. Wu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis

(2014) Jose L. Nieto-Torres et al.   PLoS Pathogens

Analysis of SARS-CoV E protein ion channel activity by tuning the protein and lipid charge

(2013) Carmina Verdiá-Báguena et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Complete Protection against Severe Acute Respiratory Syndrome Coronavirus-Mediated Lethal Respiratory Disease in Aged Mice by Immunization with a Mouse-Adapted Virus Lacking E Protein

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Inhibition of NF- B-Mediated Inflammation in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice Increases Survival

(2013) M. L. DeDiego et al.   JOURNAL OF VIROLOGY

Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate

(2013) F. Almazan et al.   mBio

Viroporins: structure and biological functions

(2012) José Luis Nieva et al.   NATURE REVIEWS MICROBIOLOGY

GalaxyWEB server for protein structure prediction and refinement

(2012) J. Ko et al.   NUCLEIC ACIDS RESEARCH

Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids

(2012) Carmina Verdiá-Báguena et al.   VIROLOGY

Fast docking using the CHARMM force field with EADock DSS

(2011) Aurélien Grosdidier et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Identification of a Golgi Complex-Targeting Signal in the Cytoplasmic Tail of the Severe Acute Respiratory Syndrome Coronavirus Envelope Protein

(2011) J. R. Cohen et al.   JOURNAL OF VIROLOGY

SwissDock, a protein-small molecule docking web service based on EADock DSS

(2011) A. Grosdidier et al.   NUCLEIC ACIDS RESEARCH

Subcellular location and topology of severe acute respiratory syndrome coronavirus envelope protein

(2011) Jose L. Nieto-Torres et al.   VIROLOGY

Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Regulates Cell Stress Response and Apoptosis

(2011) Marta L. DeDiego et al.   PLoS Pathogens

Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus

(2010) R. Acharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease

(2010) Jason Netland et al.   VIROLOGY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Structure and Inhibition of the SARS Coronavirus Envelope Protein Ion Channel

(2009) Konstantin Pervushin et al.   PLoS Pathogens

Structural Flexibility of the Pentameric SARS Coronavirus Envelope Protein Ion Channel

(2008) Krupakar Parthasarathy et al.   BIOPHYSICAL JOURNAL

A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters

(2008) E. W. Lamirande et al.   JOURNAL OF VIROLOGY

Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice

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