The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development

Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling

(2019) Georgia Gunner et al.   NATURE NEUROSCIENCE

Ocular Dominance Plasticity in Binocular Primary Visual Cortex Does Not Require C1q

(2019) Christina A. Welsh et al.   JOURNAL OF NEUROSCIENCE

Sushi repeat-containing protein X-linked 2: A novel phylogenetically conserved hypothalamo-pituitary protein

(2018) Mehwish Anwer et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Development, form, and function of the mouse visual thalamus

(2018) William Guido   JOURNAL OF NEUROPHYSIOLOGY

Sociability and synapse subtype-specific defects in mice lacking SRPX2, a language-associated gene

(2018) Breeanne M. Soteros et al.   PLoS One

CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development

(2018) Emily K. Lehrman et al.   NEURON

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice

(2017) Qiaoqiao Shi et al.   Science Translational Medicine

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

(2016) Hansen Lui et al.   CELL

Von Willebrand Factor Interacts with Surface-Bound C1q and Induces Platelet Rolling

(2016) Robert Kölm et al.   JOURNAL OF IMMUNOLOGY

A complement–microglial axis drives synapse loss during virus-induced memory impairment

(2016) Michael J. Vasek et al.   NATURE

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Coordinated Spine Pruning and Maturation Mediated by Inter-Spine Competition for Cadherin/Catenin Complexes

(2015) Wen-Jie Bian et al.   CELL

Tubacin prevents neuronal migration defects and epileptic activity caused by rat Srpx2 silencing in utero

(2013) Manal Salmi et al.   BRAIN

Remodeling of dendrites and spines in theC1qknockout model of genetic epilepsy

(2013) Yunyong Ma et al.   EPILEPSIA

The novel complement inhibitor human CUB and Sushi multiple domains 1 (CSMD1) protein promotes factor I-mediated degradation of C4b and C3b and inhibits the membrane attack complex assembly

(2013) Astrid Escudero-Esparza et al.   FASEB JOURNAL

Sushi domain-containing protein 4 (SUSD4) inhibits complement by disrupting the formation of the classical C3 convertase

(2013) Emelie Holmquist et al.   FASEB JOURNAL

TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement

(2013) Allison R Bialas et al.   NATURE NEUROSCIENCE

Nuclear Calcium Signaling in Spinal Neurons Drives a Genomic Program Required for Persistent Inflammatory Pain

(2013) Manuela Simonetti et al.   NEURON

Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites

(2013) I. Bally et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Human Language-Associated Gene SRPX2 Regulates Synapse Formation and Vocalization in Mice

(2013) G. M. Sia et al.   SCIENCE

The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease

(2012) Alexander H. Stephan et al.   Annual Review of Neuroscience

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

The complotype: dictating risk for inflammation and infection

(2012) Claire L. Harris et al.   TRENDS IN IMMUNOLOGY

The Complement Control-Related Genes CSMD1 and CSMD2 Associate to Schizophrenia

(2011) Bjarte Håvik et al.   BIOLOGICAL PSYCHIATRY

Cell Type–Specific Three-Dimensional Structure of Thalamocortical Circuits in a Column of Rat Vibrissal Cortex

(2011) Marcel Oberlaender et al.   CEREBRAL CORTEX

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Extraordinary neoteny of synaptic spines in the human prefrontal cortex

(2011) Zdravko Petanjek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Enhanced synaptic connectivity and epilepsy in C1q knockout mice

(2010) Yunxiang Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The subcellular organization of neocortical excitatory connections

(2009) Leopoldo Petreanu et al.   NATURE

Classical MHCI Molecules Regulate Retinogeniculate Refinement and Limit Ocular Dominance Plasticity

(2009) Akash Datwani et al.   NEURON

Mechanisms Underlying Development of Visual Maps and Receptive Fields

(2008) Andrew D. Huberman et al.   Annual Review of Neuroscience

Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR

(2008) Barbara Royer-Zemmour et al.   HUMAN MOLECULAR GENETICS