Tubacin prevents neuronal migration defects and epileptic activity caused by rat Srpx2 silencing in utero

A developmental and genetic classification for malformations of cortical development: update 2012

(2012) A. James Barkovich et al.   BRAIN

MEC-17 Deficiency Leads to Reduced  -Tubulin Acetylation and Impaired Migration of Cortical Neurons

(2012) L. Li et al.   JOURNAL OF NEUROSCIENCE

From prenatal genomic diagnosis to fetal personalized medicine: progress and challenges

(2012) Diana W Bianchi   NATURE MEDICINE

SRPX2 Is a Novel Chondroitin Sulfate Proteoglycan That Is Overexpressed in Gastrointestinal Cancer

(2012) Kaoru Tanaka et al.   PLoS One

Mapping Fetal Brain Development In Utero Using Magnetic Resonance Imaging: The Big Bang of Brain Mapping

(2011) Colin Studholme   Annual Review of Biomedical Engineering

Development and Evolution of the Human Neocortex

(2011) Jan H. Lui et al.   CELL

What disorders of cortical development tell us about the cortex: one plus one does not always make two

(2011) M Chiara Manzini et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The Role of the Urokinase Receptor in Epilepsy, in Disorders of Language, Cognition, Communication and Behavior, and in the Central Nervous System

(2011) Nadine Bruneau et al.   CURRENT PHARMACEUTICAL DESIGN

A glial origin for periventricular nodular heterotopia caused by impaired expression of Filamin-A

(2011) Aurelie Carabalona et al.   HUMAN MOLECULAR GENETICS

Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors

(2011) Aiqun Li et al.   NATURE CELL BIOLOGY

HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease

(2011) Constantin d'Ydewalle et al.   NATURE MEDICINE

Self-amplifying autocrine actions of BDNF in axon development

(2011) P.-L. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal migration mechanisms in development and disease

(2010) Manuel Valiente et al.   CURRENT OPINION IN NEUROBIOLOGY

Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons

(2010) A. Sessa et al.   GENES & DEVELOPMENT

TUBA1A mutations cause wide spectrum lissencephaly (smooth brain) and suggest that multiple neuronal migration pathways converge on alpha tubulins

(2010) Ravinesh A. Kumar et al.   HUMAN MOLECULAR GENETICS

Molecular networks implicated in speech-related disorders: FOXP2 regulates the SRPX2/uPAR complex

(2010) Patrice Roll et al.   HUMAN MOLECULAR GENETICS

Annual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disorders

(2010) John L.R. Rubenstein   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

The Sushi Domains of GABAB Receptors Function as Axonal Targeting Signals

(2010) B. Biermann et al.   JOURNAL OF NEUROSCIENCE

Acetylation of Microtubules Influences Their Sensitivity to Severing by Katanin in Neurons and Fibroblasts

(2010) H. Sudo et al.   JOURNAL OF NEUROSCIENCE

MEC-17 is an α-tubulin acetyltransferase

(2010) Jyothi S. Akella et al.   NATURE

An Embedded Subnetwork of Highly Active Neurons in the Neocortex

(2010) Lina Yassin et al.   NEURON

Lissencephaly: Mechanistic insights from animal models and potential therapeutic strategies

(2010) Anthony Wynshaw-Boris et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Complex Segmental Duplications Mediate a Recurrent dup(X)(p11.22-p11.23) Associated with Mental Retardation, Speech Delay, and EEG Anomalies in Males and Females

(2009) Roberto Giorda et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Histone deacetylase inhibitors that target tubulin

(2009) Jörg Schemies et al.   CANCER LETTERS

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

From rolandic epilepsy to continuous spike-and-waves during sleep and Landau-Kleffner syndromes: Insights into possible genetic factors

(2009) Gabrielle Rudolf et al.   EPILEPSIA

Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4)

(2009) Lisa J Strug et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Sushi repeat protein X-linked 2, a novel mediator of angiogenesis

(2009) Marijana Miljkovic-Licina et al.   FASEB JOURNAL

Genetic basis in epilepsies caused by malformations of cortical development and in those with structurally normal brain

(2009) Danielle M. Andrade   HUMAN GENETICS

The Urokinase Plasminogen Activator Receptor Promotes Efferocytosis of Apoptotic Cells

(2009) Veera D'mello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6

(2009) Y. Zilberman et al.   JOURNAL OF CELL SCIENCE

Abnormal Network Activity in a Targeted Genetic Model of Human Double Cortex

(2009) J. B. Ackman et al.   JOURNAL OF NEUROSCIENCE

Quantification of sunitinib in mouse plasma, brain tumor and normal brain using liquid chromatography–electrospray ionization-tandem mass spectrometry and pharmacokinetic application

(2009) Qingyu Zhou et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A secreted complement-control-related protein ensures acetylcholine receptor clustering

(2009) Marie Gendrel et al.   NATURE

Mutations in the β-tubulin gene TUBB2B result in asymmetrical polymicrogyria

(2009) Xavier Hubert Jaglin et al.   NATURE GENETICS

Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly

(2009) Masami Yamada et al.   NATURE MEDICINE

EFHC1 interacts with microtubules to regulate cell division and cortical development

(2009) Laurence de Nijs et al.   NATURE NEUROSCIENCE

Tubulin-related cortical dysgeneses: microtubule dysfunction underlying neuronal migration defects

(2009) Xavier H. Jaglin et al.   TRENDS IN GENETICS

Molecular layers underlying cytoskeletal remodelling during cortical development

(2009) Julian Ik-Tsen Heng et al.   TRENDS IN NEUROSCIENCES

Nuclear localization of a novel human syntaxin 1B isoform

(2008) Sandrine Pereira et al.   GENE

Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR

(2008) Barbara Royer-Zemmour et al.   HUMAN MOLECULAR GENETICS

SRPX2 is overexpressed in gastric cancer and promotes cellular migration and adhesion

(2008) Kaoru Tanaka et al.   INTERNATIONAL JOURNAL OF CANCER

Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

(2008) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Neurogenin 2 controls cortical neuron migration through regulation of Rnd2

(2008) Julian Ik-Tsen Heng et al.   NATURE

Dcx reexpression reduces subcortical band heterotopia and seizure threshold in an animal model of neuronal migration disorder

(2008) Jean-Bernard Manent et al.   NATURE MEDICINE

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

(2008) Aleksey G. Kazantsev et al.   NATURE REVIEWS DRUG DISCOVERY

HDAC6: a key regulator of cytoskeleton, cell migration and cell–cell interactions

(2008) Agustín Valenzuela-Fernández et al.   TRENDS IN CELL BIOLOGY

Neuro-archaeology: pre-symptomatic architecture and signature of neurological disorders

(2008) Yehezkel Ben-Ari   TRENDS IN NEUROSCIENCES

Abnormal development of the human cerebral cortex: genetics, functional consequences and treatment options

(2008) Renzo Guerrini et al.   TRENDS IN NEUROSCIENCES