Degradation of Sargassum crassifolium Fucoidan by Ascorbic Acid and Hydrogen Peroxide, and Compositional, Structural, and In Vitro Anti-Lung Cancer Analyses of the Degradation Products

The RNA-binding protein RBM47 inhibits non-small cell lung carcinoma metastasis through modulation of AXIN1 mRNA stability and Wnt/β-catentin signaling

(2020) Di-jian Shen et al.   SURGICAL ONCOLOGY-OXFORD

Low molecular weight fucoidan alleviates diabetic nephropathy by binding fibronectin and inhibiting ECM-receptor interaction in human renal mesangial cells

(2020) Jing Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Mechanisms of Bioactivities of Fucoidan from the Brown Seaweed Fucus vesiculosus L. of the Barents Sea

(2020) Olga N. Pozharitskaya et al.   Marine Drugs

In Vitro Evaluation of Anti-Colon Cancer Potential of Crude Extracts of Fucoidan Obtained from Sargassum Glaucescens Pretreated by Compressional-Puffing

(2020) Wei-Cheng Shiao et al.   Applied Sciences-Basel

Extrusion followed by ultrasound as a chemical-free pretreatment method to enhance enzymatic hydrolysis of rice hull for fermentable sugars production

(2020) Youwei Zhang et al.   INDUSTRIAL CROPS AND PRODUCTS

Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies

(2019) Yu Wang et al.   Marine Drugs

Therapeutic Effects of Fucoidan: A Review on Recent Studies

(2019) Sibusiso Luthuli et al.   Marine Drugs

The Pharmacokinetics of Fucoidan after Topical Application to Rats

(2019) Olga N. Pozharitskaya et al.   Marine Drugs

Anti-inflammatory effect of low molecular weight fucoidan from Saccharina japonica on atherosclerosis in apoE-knockout mice

(2018) Yingjie Xu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Pharmacokinetic and Tissue Distribution of Fucoidan from Fucus vesiculosus after Oral Administration to Rats

(2018) Olga Pozharitskaya et al.   Marine Drugs

Antibacterial and Antioxidant Capacities and Attenuation of Lipid Accumulation in 3T3-L1 Adipocytes by Low-Molecular-Weight Fucoidans Prepared from Compressional-Puffing-Pretreated Sargassum Crassifolium

(2018) et al.   Marine Drugs

Characterization and Antioxidant and Angiotensin I-Converting Enzyme (ACE)-Inhibitory Activities of Gelatin Hydrolysates Prepared from Extrusion-Pretreated Milkfish (Chanos chanos) Scale

(2018) Chun-Yung Huang et al.   Marine Drugs

Enhancement of Cell Adhesion, Cell Growth, Wound Healing, and Oxidative Protection by Gelatins Extracted from Extrusion-Pretreated Tilapia (Oreochromis sp.) Fish Scale

(2018) Chun-Yung Huang et al.   MOLECULES

Isolation of fucoidan from Sargassum polycystum brown algae: Structural characterization, in vitro antioxidant and anticancer activity

(2017) Subramanian Palanisamy et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Structural Determinant and Its Underlying Molecular Mechanism of STPC2 Related to Anti-Angiogenic Activity

(2017) Min Hu et al.   Marine Drugs

Compositional Characteristics and In Vitro Evaluations of Antioxidant and Neuroprotective Properties of Crude Extracts of Fucoidan Prepared from Compressional Puffing-Pretreated Sargassum crassifolium

(2017) et al.   Marine Drugs

Compressional-Puffing Pretreatment Enhances Neuroprotective Effects of Fucoidans from the Brown Seaweed Sargassum hemiphyllum on 6-Hydroxydopamine-Induced Apoptosis in SH-SY5Y Cells

(2017) Chun-Yung Huang et al.   MOLECULES

Structural elucidation of polysaccharide fractions from the brown alga Coccophora langsdorfii and in vitro investigation of their anticancer activity

(2016) Tatiana I. Imbs et al.   CARBOHYDRATE POLYMERS

The effect of extrusion processing on the physiochemical properties of extruded orange pomace

(2016) Ya-Ling Huang et al.   FOOD CHEMISTRY

Isolation and characterization of fish scale collagen from tilapia ( Oreochromis sp.) by a novel extrusion–hydro-extraction process

(2016) Chun-Yung Huang et al.   FOOD CHEMISTRY

Antioxidant activities of crude extracts of fucoidan extracted from Sargassum glaucescens by a compressional-puffing-hydrothermal extraction process

(2016) Chun-Yung Huang et al.   FOOD CHEMISTRY

The PI3K/AKT/mTOR pathway as a therapeutic target in ovarian cancer

(2015) Seiji Mabuchi et al.   GYNECOLOGIC ONCOLOGY

In vitro anticancer activity of fucoidan from Turbinaria conoides against A549 cell lines

(2015) Thangapandi Marudhupandi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Fucoidan – A α-d-glucosidase inhibitor from Sargassum wightii with relevance to type 2 diabetes mellitus therapy

(2015) T. Vinoth Kumar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Antioxidant activity and growth inhibition of human colon cancer cells by crude and purified fucoidan preparations extracted from Sargassum cristaefolium

(2015) Cheng-Yuan Wang et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

NMR use to quantify phlorotannins: The case of Cystoseira tamariscifolia, a phloroglucinol-producing brown macroalga in Brittany (France)

(2015) Camille Jégou et al.   TALANTA

Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer

(2014) Claudia Fumarola et al.   BIOCHEMICAL PHARMACOLOGY

Targeting the PI3K/AKT/mTOR pathway in estrogen receptor-positive breast cancer

(2014) Eva Maria Ciruelos Gil   CANCER TREATMENT REVIEWS

Mekabu fucoidan: Structural complexity and defensive effects against avian influenza A viruses

(2014) Andriy Synytsya et al.   CARBOHYDRATE POLYMERS

Effects of partial desulfation on antioxidant and inhibition of DLD cancer cell of Ulva fasciata polysaccharide

(2014) Ping Shao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Picking the Point of Inhibition: A Comparative Review of PI3K/AKT/mTOR Pathway Inhibitors

(2014) R. Dienstmann et al.   MOLECULAR CANCER THERAPEUTICS

Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway

(2013) Howard A. Burris   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

(2013) Jiri Polivka et al.   PHARMACOLOGY & THERAPEUTICS

Low Molecular Weight Fucoidan against Renal Ischemia–Reperfusion Injury via Inhibition of the MAPK Signaling Pathway

(2013) Jihui Chen et al.   PLoS One

Degradation and the antioxidant activity of polysaccharide from Enteromorpha linza

(2012) Zhongshan Zhang et al.   CARBOHYDRATE POLYMERS

A comparative study of the anticoagulant activities of eleven fucoidans

(2012) Weihua Jin et al.   CARBOHYDRATE POLYMERS

The PI3K/AKT/mTOR Pathway as a Therapeutic Target in Endometrial Cancer

(2012) B. M. Slomovitz et al.   CLINICAL CANCER RESEARCH

The effect of fucoidan from brown seaweed Sargassum wightii on WSSV resistance and immune activity in shrimp Penaeus monodon (Fab)

(2012) Grasian Immanuel et al.   FISH & SHELLFISH IMMUNOLOGY

Effects of twin-screw extrusion on soluble dietary fibre and physicochemical properties of soybean residue

(2012) Yan Jing et al.   FOOD CHEMISTRY

Fucoidan from Seaweed Fucus vesiculosus Inhibits Migration and Invasion of Human Lung Cancer Cell via PI3K-Akt-mTOR Pathways

(2012) Hyunkyoung Lee et al.   PLoS One

Fucoidans from Brown Seaweeds Sargassum hornery, Eclonia cava, Costaria costata: Structural Characteristics and Anticancer Activity

(2011) Svetlana Ermakova et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Pretreatment of rice straw using an extrusion/extraction process at bench-scale for producing cellulosic ethanol

(2011) Wen-Hua Chen et al.   BIORESOURCE TECHNOLOGY

Degradation of Laminaria japonica fucoidan by hydrogen peroxide and antioxidant activities of the degradation products of different molecular weights

(2011) Yun Hou et al.   CARBOHYDRATE POLYMERS

Sulfated polysaccharides from brown seaweeds Saccharina japonica and Undaria pinnatifida: isolation, structural characteristics, and antitumor activity

(2011) Olesya S. Vishchuk et al.   CARBOHYDRATE RESEARCH

Important Determinants for Fucoidan Bioactivity: A Critical Review of Structure-Function Relations and Extraction Methods for Fucose-Containing Sulfated Polysaccharides from Brown Seaweeds

(2011) Marcel Tutor Ale et al.   Marine Drugs

Fucoidan from Undaria pinnatifida Induces Apoptosis in A549 Human Lung Carcinoma Cells

(2011) Hye-Jin Boo et al.   PHYTOTHERAPY RESEARCH

Fucoidan present in brown algae induces apoptosis of human colon cancer cells

(2010) Eun Ji Kim et al.   BMC GASTROENTEROLOGY

Ocimum gratissimumAqueous Extract Induces Apoptotic Signalling in Lung Adenocarcinoma Cell A549

(2010) Han-Min Chen et al.   Evidence-based Complementary and Alternative Medicine

Higher specificity of the activity of low molecular weight fucoidan for thrombin-induced platelet aggregation

(2010) Zhixiang Zhu et al.   THROMBOSIS RESEARCH

L-rhamnose and L-fucose suppress cancer growth in mice

(2010) Pavel Tomsik et al.   Open Life Sciences

AKT/mTOR Pathway Activation and BCL-2 Family Proteins Modulate the Sensitivity of Human Small Cell Lung Cancer Cells to RAD001

(2009) M. Marinov et al.   CLINICAL CANCER RESEARCH

Targeted Therapy for Advanced Prostate Cancer: Inhibition of the PI3K/Akt/mTOR Pathway

(2009) Todd Morgan et al.   CURRENT CANCER DRUG TARGETS

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Fourier Transform Infrared (FTIR) Spectroscopy of Biological Tissues

(2008) Zanyar Movasaghi et al.   APPLIED SPECTROSCOPY REVIEWS

Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets

(2008) Laure Bachelet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Apoptosis of human intervertebral discs after trauma compares to degenerated discs involving both receptor-mediated and mitochondrial-dependent pathways

(2008) Sven K. Tschoeke et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Fucoidan: Structure and Bioactivity

(2008) Bo Li et al.   MOLECULES