Cytoskeletal organization through multivalent interactions

A Combinatorial MAP Code Dictates Polarized Microtubule Transport

(2020) Brigette Y. Monroy et al.   DEVELOPMENTAL CELL

Load‐dependent detachment kinetics plays a key role in bidirectional cargo transport by kinesin and dynein

(2019) Kazuka G. Ohashi et al.   TRAFFIC

MAP7 family proteins regulate kinesin-1 recruitment and activation

(2019) Peter Jan Hooikaas et al.   JOURNAL OF CELL BIOLOGY

Microtubules gate tau condensation to spatially regulate microtubule functions

(2019) Ruensern Tan et al.   NATURE CELL BIOLOGY

Kinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymes

(2019) Valerie Siahaan et al.   NATURE CELL BIOLOGY

Multivalent electrostatic microtubule interactions of synthetic peptides are sufficient to mimic advanced MAP-like behavior

(2019) Hauke Drechsler et al.   MOLECULAR BIOLOGY OF THE CELL

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

(2018) Danielle A. Grotjahn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Near-atomic model of microtubule-tau interactions

(2018) Elizabeth H. Kellogg et al.   SCIENCE

Diffusive tail anchorage determines velocity and force produced by kinesin-14 between crosslinked microtubules

(2018) Annemarie Lüdecke et al.   Nature Communications

Competition between microtubule-associated proteins directs motor transport

(2018) Brigette Y. Monroy et al.   Nature Communications

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

(2018) Danielle A. Grotjahn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recruitment of two dyneins to an mRNA-dependent Bicaudal D transport complex

(2018) Thomas E Sladewski et al.   eLife

Activation of mammalian cytoplasmic dynein in multi-motor motility assays

(2018) Gina A. Monzon et al.   JOURNAL OF CELL SCIENCE

Cryo-EM shows how dynactin recruits two dyneins for faster movement

(2018) Linas Urnavicius et al.   NATURE

Geometry of antiparallel microtubule bundles regulates relative sliding and stalling by PRC1 and Kif4A

(2018) Sithara Wijeratne et al.   eLife

Changes in microtubule overlap length regulate kinesin-14-driven microtubule sliding

(2017) Marcus Braun et al.   Nature Chemical Biology

Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase

(2017) Amayra Hernández-Vega et al.   Cell Reports

Entropic forces drive contraction of cytoskeletal networks

(2016) Marcus Braun et al.   BIOESSAYS

A Simple Model of Multivalent Adhesion and Its Application to Influenza Infection

(2016) Huafeng Xu et al.   BIOPHYSICAL JOURNAL

The Kinesin-1 Chemomechanical Cycle: Stepping Toward a Consensus

(2016) William O. Hancock   BIOPHYSICAL JOURNAL

Review: Mechanochemistry of the kinesin-1 ATPase

(2016) R. A. Cross   BIOPOLYMERS

Mitosis, Diffusible Crosslinkers, and the Ideal Gas Law

(2015) David J. Odde   CELL

Diffusible Crosslinkers Generate Directed Forces in Microtubule Networks

(2015) Zdenek Lansky et al.   CELL

Measuring Pushing and Braking Forces Generated by Ensembles of Kinesin-5 Crosslinking Two Microtubules

(2015) Yuta Shimamoto et al.   DEVELOPMENTAL CELL

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

Non-catalytic motor domains enable processive movement and functional diversification of the kinesin-14 Kar3

(2015) Christine Mieck et al.   eLife

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Tau interconverts between diffusive and stable populations on the microtubule surface in an isoform and lattice specific manner

(2014) Derrick P. McVicker et al.   Cytoskeleton

Minus-End-Directed Kinesin-14 Motors Align Antiparallel Microtubules to Control Metaphase Spindle Length

(2014) Austin J. Hepperla et al.   DEVELOPMENTAL CELL

In vitroreconstitution of a highly processive recombinant human dynein complex

(2014) Max A Schlager et al.   EMBO JOURNAL

Multiple-binding-site mechanism explains concentration-dependent unbinding rates of DNA-binding proteins

(2014) Charles E. Sing et al.   NUCLEIC ACIDS RESEARCH

Dimerization of mammalian kinesin-3 motors results in superprocessive motion

(2014) V. Soppina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

(2014) R. J. McKenney et al.   SCIENCE

Dynactin functions as both a dynamic tether and brake during dynein-driven motility

(2014) Swathi Ayloo et al.   Nature Communications

Phase transitions of multivalent proteins can promote clustering of membrane receptors

(2014) Sudeep Banjade et al.   eLife

Tau Protein Diffuses along the Microtubule Lattice

(2012) Maike H. Hinrichs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Measuring collective transport by defined numbers of processive and nonprocessive kinesin motors

(2012) K. Furuta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of the human cytoplasmic dynein complex

(2012) M. Trokter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive braking by Ase1 prevents overlapping microtubules from sliding completely apart

(2011) Marcus Braun et al.   NATURE CELL BIOLOGY

The Many Faces of Tau

(2011) Meaghan Morris et al.   NEURON

Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein

(2010) Radhika Subramanian et al.   CELL

Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14

(2010) Christian Hentrich et al.   JOURNAL OF CELL BIOLOGY

Cell mechanics and the cytoskeleton

(2010) Daniel A. Fletcher et al.   NATURE

Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA

(2010) J. S. Graham et al.   NUCLEIC ACIDS RESEARCH

Obstacles on the Microtubule Reduce the Processivity of Kinesin-1 in a Minimal In Vitro System and in Cell Extract

(2009) Ivo A. Telley et al.   BIOPHYSICAL JOURNAL

Kinesin-8 Motors Act Cooperatively to Mediate Length-Dependent Microtubule Depolymerization

(2009) Vladimir Varga et al.   CELL

The diffusive interaction of microtubule binding proteins

(2009) Jeremy R Cooper et al.   CURRENT OPINION IN CELL BIOLOGY

Phosphorylation-Dependent Protein Interactions at the Spindle Midzone Mediate Cell Cycle Regulation of Spindle Elongation

(2009) Anton Khmelinskii et al.   DEVELOPMENTAL CELL

The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism

(2009) Marcus Braun et al.   NATURE CELL BIOLOGY

The mitotic kinesin-14 Ncd drives directional microtubule–microtubule sliding

(2009) Gero Fink et al.   NATURE CELL BIOLOGY

Microtubule-Driven Multimerization Recruits ase1p onto Overlapping Microtubules

(2008) Lukas C. Kapitein et al.   CURRENT BIOLOGY

Anesthesia-Induced Hyperphosphorylation Detaches 3-Repeat Tau from Microtubules without Affecting Their Stability In Vivo

(2008) E. Planel et al.   JOURNAL OF NEUROSCIENCE

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

(2008) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

(2008) R. Dixit et al.   SCIENCE