Flagellar targeting of an arginine kinase requires a conserved lipidated protein intraflagellar transport (LIFT) pathway in Trypanosoma brucei

Cell Cycle-Dependent Flagellar Disassembly in a Firebug Trypanosomatid Leptomonas pyrrhocoris

(2019) Cynthia Y. He et al.   mBio

The unusual flagellar-targeting mechanism and functions of the trypanosome ortholog of the ciliary GTPase Arl13b

(2018) Yiliu Zhang et al.   JOURNAL OF CELL SCIENCE

Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery

(2017) Bram Prevo et al.   FEBS Journal

Arl3 and RP2 regulate the trafficking of ciliary tip kinesins

(2017) Nele Schwarz et al.   HUMAN MOLECULAR GENETICS

An efficient cumate-inducible system for procyclic and bloodstream form Trypanosoma brucei

(2017) Feng-Jun Li et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Genes and molecular pathways underpinning ciliopathies

(2017) Jeremy F. Reiter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TrypTag.org: A Trypanosome Genome-wide Protein Localisation Resource

(2017) Samuel Dean et al.   TRENDS IN PARASITOLOGY

Intraflagellar Transport and Ciliary Dynamics

(2017) Hiroaki Ishikawa et al.   Cold Spring Harbor Perspectives in Biology

Shuttling and sorting lipid-modified cargo into the cilia

(2016) Louise A. Stephen et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors

(2016) Christin Hanke-Gogokhia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Biochemical and Structural Insights into the Interaction of Myristoylated Cargo with Unc119 Protein and Their Release by Arl2/3

(2016) Mamta Jaiswal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An improved smaller biotin ligase for BioID proximity labeling

(2016) Dae In Kim et al.   MOLECULAR BIOLOGY OF THE CELL

The Intraflagellar Transport Machinery

(2016) Michael Taschner et al.   Cold Spring Harbor Perspectives in Biology

GTP-binding of ARL-3 is activated by ARL-13 as a GEF and stabilized by UNC-119

(2016) Qing Zhang et al.   Scientific Reports

Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite Trypanosoma brucei

(2016) Megan H. Wright et al.   ACS Infectious Diseases

The Flagellar Arginine Kinase in Trypanosoma brucei Is Important for Infection in Tsetse Flies

(2015) Cher-Pheng Ooi et al.   PLoS One

IFT–Cargo Interactions and Protein Transport in Cilia

(2015) Karl F. Lechtreck   TRENDS IN BIOCHEMICAL SCIENCES

A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins

(2015) Katja Gotthardt et al.   eLife

Proteomic Analysis of Intact Flagella of ProcyclicTrypanosoma bruceiCells Identifies Novel Flagellar Proteins with Unique Sub-localization and Dynamics

(2014) Ines Subota et al.   MOLECULAR & CELLULAR PROTEOMICS

Motility and more: the flagellum of Trypanosoma brucei

(2014) Gerasimos Langousis et al.   NATURE REVIEWS MICROBIOLOGY

UNC119a bridges the transmission of Fyn signals to Rab11, leading to the completion of cytokinesis

(2013) YuKyung Lee et al.   CELL CYCLE

The Phosphoarginine Energy-Buffering System of Trypanosoma brucei Involves Multiple Arginine Kinase Isoforms with Different Subcellular Locations

(2013) Frank Voncken et al.   PLoS One

Evolutionary cell biology of chromosome segregation: insights from trypanosomes

(2013) B. Akiyoshi et al.   Open Biology

Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119

(2012) Shehab A Ismail et al.   EMBO JOURNAL

Biochemical Characterization of the Bi-lobe Reveals a Continuous Structural Network Linking the Bi-lobe to Other Single-copied Organelles inTrypanosoma brucei

(2012) Ladan Gheiratmand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

(2012) Kyle J. Roux et al.   JOURNAL OF CELL BIOLOGY

ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting

(2012) M. C. Humbert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arl3 and RP2 mediated assembly and traffic of membrane associated cilia proteins

(2012) Nele Schwarz et al.   VISION RESEARCH

Uncoordinated (UNC)119: Coordinating the trafficking of myristoylated proteins

(2012) Ryan Constantine et al.   VISION RESEARCH

ProtTest 3: fast selection of best-fit models of protein evolution

(2011) Diego Darriba et al.   BIOINFORMATICS

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

(2011) K. J. Wright et al.   GENES & DEVELOPMENT

The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

(2011) Anchal Chandra et al.   NATURE CELL BIOLOGY

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

(2011) Shehab A Ismail et al.   Nature Chemical Biology

UNC119 is required for G protein trafficking in sensory neurons

(2011) Houbin Zhang et al.   NATURE NEUROSCIENCE

The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis

(2010) Yujie Li et al.   JOURNAL OF CELL BIOLOGY

The small GTPase ARL2 is required for cytokinesis in Trypanosoma brucei

(2010) Helen P. Price et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

(2010) Julie A. Frearson et al.   NATURE

TbUNC119 and Its Binding Protein Complex Are Essential for Propagation, Motility, and Morphogenesis of Trypanosoma brucei Procyclic Form Cells

(2010) Shigeru Ohshima et al.   PLoS One

UNC119 inhibits dynamin and dynamin-dependent endocytic processes

(2009) Zunayet Karim et al.   CELLULAR SIGNALLING

Uncoordinated 119 Protein Controls Trafficking of Lck via the Rab11 Endosome and Is Critical for Immunological Synapse Formation

(2009) M. M. Gorska et al.   JOURNAL OF IMMUNOLOGY

Myristoyl-CoA:protein N-myristoyltransferase depletion in trypanosomes causes avirulence and endocytic defects

(2009) Helen P. Price et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Expression and cellular localisation of calpain-like proteins in Trypanosoma brucei

(2009) Wen Liu et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3

(2008) Stefan Veltel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY