Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening

Human iPSC‐derived microglia: A growing toolset to study the brain's innate immune cells

(2020) Jonathan Hasselmann et al.   GLIA

Cyclic AMP Regulates Key Features of Macrophages via PKA: Recruitment, Reprogramming and Efferocytosis

(2020) Graziele L. Negreiros-Lima et al.   Cells

Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia

(2020) Benjamin J. Andreone et al.   NATURE NEUROSCIENCE

The cAMP Pathway Amplifies Early MyD88-Dependent and Type I Interferon-Independent LPS-Induced Interleukin-10 Expression in Mouse Macrophages

(2019) Orna Ernst et al.   MEDIATORS OF INFLAMMATION

Effect of (R)‐salbutamol on the switch of phenotype and metabolic pattern in LPS‐induced macrophage cells

(2019) Shanping Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Human-induced pluripotent stem cell-derived macrophages and their immunological function in response to tuberculosis infection

(2018) Danping Hong et al.   Stem Cell Research & Therapy

Cyclic AMP Pathway Suppress Autoimmune Neuroinflammation by Inhibiting Functions of Encephalitogenic CD4 T Cells and Enhancing M2 Macrophage Polarization at the Site of Inflammation

(2018) Tatyana Veremeyko et al.   Frontiers in Immunology

Peroxisome Proliferator-Activated Receptor-γ Modulates the Response of Macrophages to Lipopolysaccharide and Glucocorticoids

(2018) Michael Heming et al.   Frontiers in Immunology

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study

(2018) Viola Volpato et al.   Stem Cell Reports

Boosting mTOR-dependent autophagy via upstream TLR4-MyD88-MAPK signalling and downstream NF-κB pathway quenches intestinal inflammation and oxidative stress injury

(2018) Mingxia Zhou et al.   EBioMedicine

Development and validation of a simplified method to generate human microglia from pluripotent stem cells

(2018) Amanda McQuade et al.   Molecular Neurodegeneration

Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections

(2018) Mania Ackermann et al.   Nature Communications

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function

(2017) Kazuyuki Takata et al.   IMMUNITY

Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB -Independent Tissue-Resident Macrophages

(2017) Julian Buchrieser et al.   Stem Cell Reports

Directed Differentiation of Human Pluripotent Stem Cells to Microglia

(2017) Panagiotis Douvaras et al.   Stem Cell Reports

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response

(2017) Walther Haenseler et al.   Stem Cell Reports

Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages

(2017) Walther Haenseler et al.   Scientific Reports

Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages

(2016) Nicola J. Darling et al.   BIOCHEMICAL JOURNAL

MultiQC: summarize analysis results for multiple tools and samples in a single report

(2016) Philip Ewels et al.   BIOINFORMATICS

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons

(2016) Hugo J.R. Fernandes et al.   Stem Cell Reports

Functional Analysis and Transcriptomic Profiling of iPSC-Derived Macrophages and Their Application in Modeling Mendelian Disease

(2015) H. Zhang et al.   CIRCULATION RESEARCH

Misoprostol modulates cytokine expression through a cAMP pathway: Potential therapeutic implication for liver disease

(2015) Leila Gobejishvili et al.   CLINICAL IMMUNOLOGY

Tissue-resident macrophages originate from yolk sac-derived erythro-myeloid progenitors

(2015) Elisa Gomez Perdiguero et al.   EXPERIMENTAL HEMATOLOGY

Most Tissue-Resident Macrophages Except Microglia Are Derived from Fetal Hematopoietic Stem Cells

(2015) Jianpeng Sheng et al.   IMMUNITY

Cytosolic phospholipase A2: physiological function and role in disease

(2015) Christina C. Leslie   JOURNAL OF LIPID RESEARCH

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Ontogeny of Tissue-Resident Macrophages

(2015) Guillaume Hoeffel et al.   Frontiers in Immunology

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

(2014) Slava Epelman et al.   IMMUNITY

Extracellular Signal-regulated Kinase Mediates Expression of Arginase II but Not Inducible Nitric-oxide Synthase in Lipopolysaccharide-stimulated Macrophages

(2014) Yi Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2

(2014) Koutaro Takamatsu et al.   Stem Cell Research

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Monocytes, Peripheral Blood Mononuclear Cells, and THP-1 Cells Exhibit Different Cytokine Expression Patterns following Stimulation with Lipopolysaccharide

(2013) Anita Schildberger et al.   MEDIATORS OF INFLAMMATION

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Efficient, Long Term Production of Monocyte-Derived Macrophages from Human Pluripotent Stem Cells under Partly-Defined and Fully-Defined Conditions

(2013) Bonnie van Wilgenburg et al.   PLoS One

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Macrophage polarization and plasticity in health and disease

(2012) Subhra K. Biswas et al.   IMMUNOLOGIC RESEARCH

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Generation of dendritic cells and macrophages from human induced pluripotent stem cells aiming at cell therapy

(2011) S Senju et al.   GENE THERAPY

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Tumor-secreted PGE2Inhibits CCL5 Production in Activated Macrophages through cAMP/PKA Signaling Pathway

(2010) Xuesong Qian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retinoid X receptor   controls innate inflammatory responses through the up-regulation of chemokine expression

(2010) V. Nunez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3

(2008) Karl R. Karlsson et al.   EXPERIMENTAL HEMATOLOGY

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Macrophage polarization in tumour progression

(2008) Antonio Sica et al.   SEMINARS IN CANCER BIOLOGY

Macrophages: An elusive yet emerging therapeutic target of atherosclerosis

(2007) R.L. Tiwari et al.   MEDICINAL RESEARCH REVIEWS