TLR3 promotes hepatocyte proliferation after partial hepatectomy by stimulating uPA expression and the release of tissue‐bound HGF

IL ‐6 trans‐signaling controls liver regeneration after partial hepatectomy

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Characterization of Pattern Recognition Receptor Expression and Functionality in Liver Primary Cells and Derived Cell Lines

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Cytosolic nucleic acid sensors of the innate immune system promote liver regeneration after partial hepatectomy

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Exosome-mediated activation of toll-like receptor 3 in stellate cells stimulates interleukin-17 production by γδ T cells in liver fibrosis

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Combined systemic elimination of MET and epidermal growth factor receptor signaling completely abolishes liver regeneration and leads to liver decompensation

(2016) Shirish Paranjpe et al.   HEPATOLOGY

dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration

(2015) Amanda M. Nelson et al.   Cell Stem Cell

Hepatocytes as Immunological Agents

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Diverse routes to liver regeneration

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Induction and contribution of beta platelet-derived growth factor signalling by hepatic stellate cells to liver regeneration after partial hepatectomy in mice

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Quiescent Hepatic Stellate Cells Functionally Contribute to the Hepatic Innate Immune Response via TLR3

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Toll-like receptor 3 in viral pathogenesis: friend or foe?

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Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

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Molecular mechanisms underlying RB protein function

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dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8

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Liver sinusoidal endothelial cell progenitor cells promote liver regeneration in rats

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Cleaved/Associated TLR3 Represents the Primary Form of the Signaling Receptor

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Ultraviolet radiation damages self noncoding RNA and is detected by TLR3

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Nucleic Acid Recognition by the Innate Immune System

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Toll-like receptor 4 and myeloid differentiation factor 88 provide mechanistic insights into the cause and effects of interleukin-6 activation in mouse liver regeneration

(2011) Javier Vaquero et al.   HEPATOLOGY

New concepts in liver regeneration

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cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

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Ketamine Depresses Toll-Like Receptor 3 Signaling in Spinal Microglia in a Rat Model of Neuropathic Pain

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Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

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RNA Interference Against Hepatic Epidermal Growth Factor Receptor Has Suppressive Effects on Liver Regeneration in Rats

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

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Loss of c-Met Disrupts Gene Expression Program Required for G2/M Progression during Liver Regeneration in Mice

(2010) Valentina M. Factor et al.   PLoS One

Toll-like receptor 3 signaling attenuates liver regeneration

(2009) Elina Zorde-Khvalevsky et al.   HEPATOLOGY

TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

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A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice

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