Development of early diagnosis of Parkinson's disease: Illusion or reality?

Diagnosis and Treatment of Parkinson Disease

(2020) Melissa J. Armstrong et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Implications of the Gut Microbiome in Parkinson's Disease

(2020) Mohamed Elfil et al.   MOVEMENT DISORDERS

VCP expression decrease as a biomarker of preclinical and early clinical stages of Parkinson’s disease

(2020) Anelya Alieva et al.   Scientific Reports

Parkinson’s disease treatment: past, present, and future

(2020) John D. Elsworth   JOURNAL OF NEURAL TRANSMISSION

Prodromal Parkinson's Disease: The Decade Past, the Decade to Come

(2019) Ronald B. Postuma et al.   MOVEMENT DISORDERS

Mitochondrial integrity in neurodegeneration

(2019) Katrina Cowan et al.   CNS Neuroscience & Therapeutics

In vivo, in vitro and pharmacologic models of Parkinson's disease

(2019) S. Salari et al.   PHYSIOLOGICAL RESEARCH

Proteomics in Human Parkinson’s Disease: Present Scenario and Future Directions

(2019) Anubhuti Dixit et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

MicroRNA-190 alleviates neuronal damage and inhibits neuroinflammation via Nlrp3 in MPTP-induced Parkinson's disease mouse model

(2019) Qiang Sun et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology

(2019) David K. Simon et al.   CLINICS IN GERIATRIC MEDICINE

The genetic architecture of Parkinson's disease

(2019) Cornelis Blauwendraat et al.   LANCET NEUROLOGY

Biomarkers for Parkinson’s Disease: How Good Are They?

(2019) Tianbai Li et al.   Neuroscience Bulletin

The genetics of Parkinson disease

(2018) Hao Deng et al.   AGEING RESEARCH REVIEWS

Enteric nervous system manifestations of neurodegenerative disease

(2018) Alcmène Chalazonitis et al.   BRAIN RESEARCH

Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles

(2018) Stewart F. Graham et al.   JOURNAL OF PROTEOME RESEARCH

Peripheral Biomarkers for Early Detection of Alzheimer’s and Parkinson’s Diseases

(2018) Thein Than Htike et al.   MOLECULAR NEUROBIOLOGY

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Diagnostic Criteria for Parkinson’s Disease: From James Parkinson to the Concept of Prodromal Disease

(2018) Luca Marsili et al.   Frontiers in Neurology

Diagnostic biomarkers for Parkinson’s disease at a glance: where are we?

(2018) Ilaria Cova et al.   JOURNAL OF NEURAL TRANSMISSION

Upgraded Methodology for the Development of Early Diagnosis of Parkinson’s Disease Based on Searching Blood Markers in Patients and Experimental Models

(2018) Alexander Kim et al.   MOLECULAR NEUROBIOLOGY

The importance of preclinical diagnostics in Parkinson disease

(2018) Sneha Mantri et al.   PARKINSONISM & RELATED DISORDERS

Intérêt des tests de provocation nasale pour le pneumologue

(2018) V. Doyen et al.   REVUE DES MALADIES RESPIRATOIRES

Finding useful biomarkers for Parkinson’s disease

(2018) Alice S. Chen-Plotkin et al.   Science Translational Medicine

Parkinson’s Disease: Biomarkers, Treatment, and Risk Factors

(2018) Fatemeh N. Emamzadeh et al.   Frontiers in Neuroscience

Cellular and Molecular Aspects of Parkinson Treatment: Future Therapeutic Perspectives

(2018) Khosro Jamebozorgi et al.   MOLECULAR NEUROBIOLOGY

Recent Advances in Biomarkers for Parkinson’s Disease

(2018) Runcheng He et al.   Frontiers in Aging Neuroscience

Compensatory mechanisms in Parkinson's disease: Circuits adaptations and role in disease modification

(2017) Javier Blesa et al.   EXPERIMENTAL NEUROLOGY

Pro and Contra: Provocation Tests in Drug Hypersensitivity

(2017) Ozge Soyer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MPTP Mouse Model of Preclinical and Clinical Parkinson’s Disease as an Instrument for Translational Medicine

(2017) Eduard R. Mingazov et al.   MOLECULAR NEUROBIOLOGY

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

(2017) J.A. Obeso et al.   MOVEMENT DISORDERS

Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features

(2017) Jennifer G. Goldman et al.   MOVEMENT DISORDERS

Cooperative synthesis of dopamine by non-dopaminergic neurons as a compensatory mechanism in the striatum of mice with MPTP-induced Parkinsonism

(2017) Elena A. Kozina et al.   NEUROBIOLOGY OF DISEASE

Skin nerve phosphorylated α-synuclein deposits in idiopathic REM sleep behavior disorder

(2017) Elena Antelmi et al.   NEUROLOGY

Can Biomarkers Help the Early Diagnosis of Parkinson’s Disease?

(2017) Weidong Le et al.   Neuroscience Bulletin

Direct and indirect cost of managing alzheimer’s disease and related dementias in the United States

(2017) Arijita Deb et al.   Expert Review of Pharmacoeconomics & Outcomes Research

The Proteasome Inhibition Model of Parkinson’s Disease

(2017) Eduard Bentea et al.   Journal of Parkinsons Disease

Conversion to Parkinson Disease in the PARS Hyposmic and Dopamine Transporter–Deficit Prodromal Cohort

(2017) Danna Jennings et al.   JAMA Neurology

MicroRNAs and Target Genes As Biomarkers for the Diagnosis of Early Onset of Parkinson Disease

(2017) Ahmad R. Arshad et al.   Frontiers in Molecular Neuroscience

Neuroimaging in pre-motor Parkinson's disease

(2017) Thomas R. Barber et al.   NeuroImage-Clinical

Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction

(2016) P. Bishop et al.   BIOCHEMICAL JOURNAL

Position Emission Tomography/Single-Photon Emission Tomography Neuroimaging for Detection of Premotor Parkinson's Disease

(2016) Jing Zou et al.   CNS Neuroscience & Therapeutics

Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment

(2016) Mojtaba Golpich et al.   CNS Neuroscience & Therapeutics

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: UPDATE ON GROWTH HORMONE STIMULATION TESTING AND PROPOSED REVISED CUT-POINT FOR THE GLUCAGON STIMULATION TEST IN THE DIAGNOSIS OF ADULT GROWTH HORMONE DEFICIENCY

(2016) Kevin C.J. Yuen et al.   Endocrine Practice

The prediagnostic phase of Parkinson's disease

(2016) Alastair John Noyce et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Antioxidant and inflammatory biomarkers for the identification of prodromal Parkinson's disease

(2016) Jonica Campolo et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Reversible Pharmacological Induction of Motor Symptoms in MPTP-Treated Mice at the Presymptomatic Stage of Parkinsonism: Potential Use for Early Diagnosis of Parkinson’s Disease

(2016) Gulnara R. Khakimova et al.   MOLECULAR NEUROBIOLOGY

Transcriptome Profile Changes in Mice with MPTP-Induced Early Stages of Parkinson’s Disease

(2016) Anelya Kh. Alieva et al.   MOLECULAR NEUROBIOLOGY

Longitudinal changes in CSF alpha-synuclein species reflect Parkinson's disease progression

(2016) Nour K. Majbour et al.   MOVEMENT DISORDERS

Advances in markers of prodromal Parkinson disease

(2016) Ronald B. Postuma et al.   Nature Reviews Neurology

Metabolic Biomarkers and Neurodegeneration: A Pathway Enrichment Analysis of Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis

(2016) Medi Kori et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Biomarkers in Parkinson's disease: Advances and strategies

(2016) Marion Delenclos et al.   PARKINSONISM & RELATED DISORDERS

Recent developments in circulating biomarkers in Parkinson’s disease: the potential use of miRNAs in a clinical setting

(2016) Marcia Cristina Teixeira dos Santos et al.   Bioanalysis

Parkinson's Disease and Neurodegeneration: GABA-Collapse Hypothesis

(2016) Janusz W. Błaszczyk   Frontiers in Neuroscience

Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson’s Disease

(2016) Giorgio Vivacqua et al.   PLoS One

In vivodiagnosis of allergic diseases-allergen provocation tests

(2015) I. Agache et al.   ALLERGY

Skin nerve misfolded α-synuclein in pure autonomic failure and Parkinson disease

(2015) Vincenzo Donadio et al.   ANNALS OF NEUROLOGY

Advances in Biomarker Research in Parkinson’s Disease

(2015) Shyamal H. Mehta et al.   Current Neurology and Neuroscience Reports

Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study

(2015) Mike A Nalls et al.   LANCET NEUROLOGY

Biomarkers of Parkinson’s disease: Present and future

(2015) Diane B. Miller et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

MDS clinical diagnostic criteria for Parkinson's disease

(2015) Ronald B. Postuma et al.   MOVEMENT DISORDERS

MDS research criteria for prodromal Parkinson's disease

(2015) Daniela Berg et al.   MOVEMENT DISORDERS

The diagnostic value of minor salivary gland biopsy in clinically diagnosed patients with Parkinson’s disease: comparison with DAT PET scans

(2015) Liyan Gao et al.   NEUROLOGICAL SCIENCES

Parkinson risk in idiopathic REM sleep behavior disorder: Preparing for neuroprotective trials

(2015) R. B. Postuma et al.   NEUROLOGY

Detection of α-synuclein oligomers in red blood cells as a potential biomarker of Parkinson’s disease

(2015) Xuemei Wang et al.   NEUROSCIENCE LETTERS

Elevated excretion of biopyrrin as a new marker for idiopathic Parkinson's disease

(2015) Hemi Luan et al.   PARKINSONISM & RELATED DISORDERS

Elevated salivary protein in Parkinson's disease and salivary DJ-1 as a potential marker of disease severity

(2015) Joseph M. Masters et al.   PARKINSONISM & RELATED DISORDERS

Gastrointestinal Biopsies for the Diagnosis of Alpha-Synuclein Pathology in Parkinson’s Disease

(2015) Maria Graciela Cersosimo   Gastroenterology Research and Practice

Estimating the direct and indirect costs associated with Parkinson’s disease

(2015) Carmen Rodríguez-Blázquez et al.   Expert Review of Pharmacoeconomics & Outcomes Research

Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease

(2014) Cassia R. Overk et al.   BIOCHEMICAL PHARMACOLOGY

Novel insights into the pathophysiology of different forms of stress testing

(2014) Thomas Hochgruber et al.   CLINICAL BIOCHEMISTRY

Synopsis on the Linkage of Alzheimer's and Parkinson's Disease with Chronic Diseases

(2014) Nasimudeen R. Jabir et al.   CNS Neuroscience & Therapeutics

The discovery and development of new potential antioxidant agents for the treatment of neurodegenerative diseases

(2014) Chhanda Charan Danta et al.   Expert Opinion on Drug Discovery

Cerebrospinal fluid alpha-synuclein as a biomarker for Parkinson's disease diagnosis: a systematic review and meta-analysis

(2014) Liang Gao et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Prion-like Properties of Tau Protein: The Importance of Extracellular Tau as a Therapeutic Target

(2014) Brandon B. Holmes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidized DJ-1 as a possible biomarker of Parkinson’s disease

(2014) Yoshiro Saito   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Tyrosine hydroxylase expression and activity in nigrostriatal dopaminergic neurons of MPTP-treated mice at the presymptomatic and symptomatic stages of parkinsonism

(2014) Elena A. Kozina et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Lower plasma apolipoprotein A1 levels are found in Parkinson's disease and associate with apolipoprotein A1 genotype

(2014) Christine R. Swanson et al.   MOVEMENT DISORDERS

Longitudinal assessment of tau and amyloid beta in cerebrospinal fluid of Parkinson disease

(2013) Jing Zhang et al.   ACTA NEUROPATHOLOGICA

Dopaminergic modulation of the reward system in schizophrenia: A placebo-controlled dopamine depletion fMRI study

(2013) Fabiana da Silva Alves et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Dopamine Receptor D3 Expressed on CD4+ T Cells Favors Neurodegeneration of Dopaminergic Neurons during Parkinson's Disease

(2013) H. Gonzalez et al.   JOURNAL OF IMMUNOLOGY

Cellular and Molecular Mediators of Neuroinflammation in the Pathogenesis of Parkinson’s Disease

(2013) Sandeep Vasant More et al.   MEDIATORS OF INFLAMMATION

Cerebrospinal fluid biomarkers in Parkinson disease

(2013) Lucilla Parnetti et al.   Nature Reviews Neurology

Biomarkers in Parkinson’s disease (recent update)

(2013) Sushil Sharma et al.   NEUROCHEMISTRY INTERNATIONAL

 -Synuclein in cutaneous autonomic nerves

(2013) N. Wang et al.   NEUROLOGY

Inflammation and Adaptive Immunity in Parkinson's Disease

(2013) R. L. Mosley et al.   Cold Spring Harbor Perspectives in Medicine

Meta-analysis of early nonmotor features and risk factors for Parkinson disease

(2012) Alastair J. Noyce et al.   ANNALS OF NEUROLOGY

Cerebrospinal fluid biomarkers of central catecholamine deficiency in Parkinson’s disease and other synucleinopathies

(2012) David S. Goldstein et al.   BRAIN

New concepts in the early and preclinical detection of Parkinson’s disease: therapeutic implications

(2012) Rizwan S Akhtar et al.   Expert Review of Neurotherapeutics

Biochemical premotor biomarkers for Parkinson's disease

(2012) Brit Mollenhauer et al.   MOVEMENT DISORDERS

Non-motor symptoms of Parkinson’s disease in China: A review of the literature

(2012) Wei Chen et al.   PARKINSONISM & RELATED DISORDERS

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Evaluation and Treatment of Adult Growth Hormone Deficiency: An Endocrine Society Clinical Practice Guideline

(2011) Mark E. Molitch et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Olfaction in Parkinson's disease and related disorders

(2011) Richard L. Doty   NEUROBIOLOGY OF DISEASE

Modeling of presymptomatic and symptomatic stages of parkinsonism in mice

(2011) M.V. Ugrumov et al.   NEUROSCIENCE

Neuroinflammation in Parkinson's disease

(2011) Etienne C. Hirsch et al.   PARKINSONISM & RELATED DISORDERS

CSF and plasma concentrations of free norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC), 3,4-dihydroxyphenylalanine (DOPA), and epinephrine in Parkinson's disease.

(2010) E. Eldrup et al.   ACTA NEUROLOGICA SCANDINAVICA

Detection of elevated levels of  -synuclein oligomers in CSF from patients with Parkinson disease

(2010) T. Tokuda et al.   NEUROLOGY

What are biomarkers?

(2010) Kyle Strimbu et al.   Current Opinion in HIV and AIDS

Urate as a Predictor of the Rate of Clinical Decline in Parkinson Disease

(2009) Alberto Ascherio   ARCHIVES OF NEUROLOGY

Serum levels of brain-derived neurotrophic factor correlate with motor impairment in Parkinson’s disease

(2009) Paula Scalzo et al.   JOURNAL OF NEUROLOGY

Optimization of the intravenous glucose tolerance test in T2DM patients using optimal experimental design

(2009) Hanna E. Silber et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Proteomics in human Parkinson's disease research

(2009) Virginie Licker et al.   Journal of Proteomics

Biological fluid biomarkers in neurodegenerative parkinsonism

(2009) Michael Eller et al.   Nature Reviews Neurology

Medical records documentation of constipation preceding Parkinson disease: A case-control study

(2009) R. Savica et al.   NEUROLOGY

Adrenergic supersensitivity in Parkinsonians with orthostatic hypotension

(2008) J. M. SENARD et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

AMPT-induced monoamine depletion in humans: evaluation of two alternative [123I]IBZM SPECT procedures

(2008) Erik Boot et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING