Role of pericyte‐derived SENP1 in neuronal injury after brain ischemia

Endothelium-Derived Semaphorin 3G Regulates Hippocampal Synaptic Structure and Plasticity via Neuropilin-2/PlexinA4

(2019) Chao Tan et al.   NEURON

Macrophages reprogram after ischemic stroke and promote efferocytosis and inflammation resolution in the mouse brain

(2019) Wenting Zhang et al.   CNS Neuroscience & Therapeutics

Neuroprotective effects of protein tyrosine phosphatase 1B inhibitor on cerebral ischemia/reperfusion in mice

(2018) Meiling Sun et al.   BRAIN RESEARCH

Myt1l induced direct reprogramming of pericytes into cholinergic neurons

(2018) Xing-Guang Liang et al.   CNS Neuroscience & Therapeutics

PDGFR-β restores blood-brain barrier functions in a mouse model of focal cerebral ischemia

(2018) Jie Shen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

KY-226 Protects Blood–brain Barrier Function Through the Akt/FoxO1 Signaling Pathway in Brain Ischemia

(2018) Meiling Sun et al.   NEUROSCIENCE

SUMOylation in brain ischemia: Patterns, targets, and translational implications

(2017) Joshua D Bernstock et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pericytes secrete pro-regenerative molecules in response to platelet-derived growth factor-BB

(2017) Abderahim Gaceb et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neurovascular unit crosstalk: Pericytes and astrocytes modify cytokine secretion patterns of brain endothelial cells

(2017) William A Banks et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

αII Spectrin Forms a Periodic Cytoskeleton at the Axon Initial Segment and Is Required for Nervous System Function

(2017) Claire Yu-Mei Huang et al.   JOURNAL OF NEUROSCIENCE

The role of SUMOylation in cerebral hypoxia and ischemia

(2017) Myriam Peters et al.   NEUROCHEMISTRY INTERNATIONAL

Neuron-specific SUMO knockdown suppresses global gene expression response and worsens functional outcome after transient forebrain ischemia in mice

(2017) Lin Zhang et al.   NEUROSCIENCE

From the Cover: Comparative Proteomics Reveals Silver Nanoparticles Alter Fatty Acid Metabolism and Amyloid Beta Clearance for Neuronal Apoptosis in a Triple Cell Coculture Model of the Blood–Brain Barrier

(2017) Ho-Chen Lin et al.   TOXICOLOGICAL SCIENCES

A central role for calcineurin in protein misfolding neurodegenerative diseases

(2016) Syed Zahid Ali Shah et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Model of minor stroke with mild peri-infarct ischemic injury

(2016) Ursula I. Tuor et al.   JOURNAL OF NEUROSCIENCE METHODS

Pericytes of the neurovascular unit: key functions and signaling pathways

(2016) Melanie D Sweeney et al.   NATURE NEUROSCIENCE

Neurovascular coupling protects neurons against hypoxic injury via inhibition of potassium currents by generation of nitric oxide in direct neuron and endothelium cocultures

(2016) Kun-Wei Wu et al.   NEUROSCIENCE

SUMO-specific protease 1 protects neurons from apoptotic death during transient brain ischemia/reperfusion

(2016) Huijun Zhang et al.   Cell Death & Disease

Pericytes in Brain Injury and Repair After Ischemic Stroke

(2016) Wei Cai et al.   Translational Stroke Research

P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy

(2015) Huan Wang et al.   CELL RESEARCH

Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy

(2015) Rong Cai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A Triple Culture Model of the Blood-Brain Barrier Using Porcine Brain Endothelial cells, Astrocytes and Pericytes

(2015) Louiza Bohn Thomsen et al.   PLoS One

SENP1 protects against myocardial ischaemia/reperfusion injury via a HIF1α-dependent pathway

(2014) Jianmin Gu et al.   CARDIOVASCULAR RESEARCH

In VivoTwo-photon Fluorescence Microscopy Reveals Disturbed Cerebral Capillary Blood Flow and Increased Susceptibility to Ischemic Insults in Diabetic Mice

(2014) Ji-Yun Huang et al.   CNS Neuroscience & Therapeutics

Angiopoietin 2 Induces Pericyte Apoptosis via  3 1 Integrin Signaling in Diabetic Retinopathy

(2014) S. W. Park et al.   DIABETES

SUMO2/3 is Associated with Ubiquitinated Protein Aggregates in the Mouse Neocortex after Middle Cerebral Artery Occlusion

(2014) Karin Hochrainer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

The Role of SUMO-Conjugating Enzyme Ubc9 in the Neuroprotection of Isoflurane Preconditioning Against Ischemic Neuronal Injury

(2014) Li Tong et al.   MOLECULAR NEUROBIOLOGY

In Vitro Models of the Blood–Brain Barrier for the Study of Drug Delivery to the Brain

(2014) Imola Wilhelm et al.   MOLECULAR PHARMACEUTICS

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance

(2014) Yang-ja Lee et al.   Frontiers in Cellular Neuroscience

Nitrosative Stress Induces Peroxiredoxin 1 Ubiquitination During Ischemic Insult via E6AP Activation in Endothelial Cells Both In Vitro and In Vivo

(2013) Rong-Rong Tao et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative Stress and Pathophysiology of Ischemic Stroke: Novel Therapeutic Opportunities

(2013) Ramon Rodrigo et al.   CNS & Neurological Disorders-Drug Targets

mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex

(2013) Allissa A Dillman et al.   NATURE NEUROSCIENCE

Neuroprotection After Stroke by Targeting NOX4 As a Source of Oxidative Stress

(2012) Kim A. Radermacher et al.   ANTIOXIDANTS & REDOX SIGNALING

Targeting Nitrosative Stress for Neurovascular Protection: New Implications in Brain Diseases

(2012) Rong-Rong Tao et al.   CURRENT DRUG TARGETS

Early Loss of Pericytes and Perivascular Stromal Cell-Induced Scar Formation after Stroke

(2012) Francisco Fernández-Klett et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Spatial and Temporal Gene Expression Differences in Core and Periinfarct Areas in Experimental Stroke: A Microarray Analysis

(2012) Jaime Ramos-Cejudo et al.   PLoS One

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R

(2011) Hanbo Chen et al.   BMC BIOINFORMATICS

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

(2011) Kyung-Sun Heo et al.   JOURNAL OF CELL BIOLOGY

Enhanced SUMOylation and SENP-1 Protein Levels following Oxygen and Glucose Deprivation in Neurones

(2011) Helena Cimarosti et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis

(2010) Luyang Yu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A rotarod test for evaluation of motor skill learning

(2010) Hiromi Shiotsuki et al.   JOURNAL OF NEUROSCIENCE METHODS

Ischemic preconditioning attenuates of ischemia-induced degradation of spectrin and tau: implications for ischemic tolerance

(2010) Takayuki Nakajima et al.   NEUROLOGICAL SCIENCES

Sumo-2/3-ylation following in vitro modeled ischemia is reduced in delayed ischemic tolerance

(2009) Liam T. Loftus et al.   BRAIN RESEARCH

Neuron Protection as a Therapeutic Target in Acute Ischemic Stroke

(2009) Antonino Tuttolomondo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

SUMOylation participates in induction of ischemic tolerance

(2009) Yang ja Lee et al.   JOURNAL OF NEUROCHEMISTRY

Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery

(2009) Muge Yemisci et al.   NATURE MEDICINE

SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis

(2008) X Li et al.   CELL DEATH AND DIFFERENTIATION

Transient Focal Cerebral Ischemia Induces a Dramatic Activation of Small Ubiquitin-Like Modifier Conjugation

(2008) Wei Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Increased protein SUMOylation following focal cerebral ischemia

(2007) Helena Cimarosti et al.   NEUROPHARMACOLOGY