From the Cover: Comparative Proteomics Reveals Silver Nanoparticles Alter Fatty Acid Metabolism and Amyloid Beta Clearance for Neuronal Apoptosis in a Triple Cell Coculture Model of the Blood–Brain Barrier

Testing the Neurovascular Hypothesis of Alzheimer's Disease: LRP-1 Antisense Reduces Blood-brain Barrier Clearance, Increases Brain Levels of Amyloid-β Protein, and Impairs Cognition

(2017) Laura B. Jaeger et al.   JOURNAL OF ALZHEIMERS DISEASE

Influence of silver and titanium dioxide nanoparticles on in vitro blood-brain barrier permeability

(2016) I-Chieh Chen et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Copper Exposure Perturbs Brain Inflammatory Responses and Impairs Clearance of Amyloid-Beta

(2016) Masashi Kitazawa et al.   TOXICOLOGICAL SCIENCES

Transcriptomic gene-network analysis of exposure to silver nanoparticle reveals potentially neurodegenerative progression in mouse brain neural cells

(2016) Ho-Chen Lin et al.   TOXICOLOGY IN VITRO

Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells

(2016) Keng-Poo Tan et al.   Cell Death & Disease

Involvement of inflammation in Alzheimer’s disease pathogenesis and therapeutic potential of anti-inflammatory agents

(2015) Sina Shadfar et al.   ARCHIVES OF PHARMACAL RESEARCH

Increased CSF A  during the very early phase of cerebral A  deposition in mouse models

(2015) L. F. Maia et al.   EMBO Molecular Medicine

Silver nanoparticles affect on gene expression of inflammatory and neurodegenerative responses in mouse brain neural cells

(2015) Chin-Lin Huang et al.   ENVIRONMENTAL RESEARCH

Insights into the Cellular Response Triggered by Silver Nanoparticles Using Quantitative Proteomics

(2014) Thiago Verano-Braga et al.   ACS Nano

Oleate prevents palmitate-induced mitochondrial dysfunction, insulin resistance and inflammatory signaling in neuronal cells

(2014) Bumsup Kwon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The effect of inflammatory cell-derived MCP-1 loss on neuronal survival during chronic neuroinflammation

(2014) Andrew J. Sawyer et al.   BIOMATERIALS

Palmitic Acid-Induced Neuron Cell Cycle G2/M Arrest and Endoplasmic Reticular Stress through Protein Palmitoylation in SH-SY5Y Human Neuroblastoma Cells

(2014) Yung-Hsuan Hsiao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

In vitro toxicity of silver nanoparticles to kiwifruit pollen exhibits peculiar traits beyond the cause of silver ion release

(2013) Anna Speranza et al.   ENVIRONMENTAL POLLUTION

Quantitative Assessment of In-solution Digestion Efficiency Identifies Optimal Protocols for Unbiased Protein Analysis

(2013) Ileana R. León et al.   MOLECULAR & CELLULAR PROTEOMICS

In vivo human time-exposure study of orally dosed commercial silver nanoparticles

(2013) Mark A. Munger et al.   Nanomedicine-Nanotechnology Biology and Medicine

Effects of Interleukin-6 on the Expression of Tight Junction Proteins in Isolated Cerebral Microvessels from Yearling and Adult Sheep

(2013) Susan S. Cohen et al.   NEUROIMMUNOMODULATION

The very many faces of presenilins and the γ-secretase complex

(2013) Michalina Smolarkiewicz et al.   PROTOPLASMA

Silver nanoparticles (AgNPs) cause degeneration of cytoskeleton and disrupt synaptic machinery of cultured cortical neurons

(2013) Fenglian Xu et al.   Molecular Brain

Tight Junction in Blood-Brain Barrier: An Overview of Structure, Regulation, and Regulator Substances

(2012) Wei-Ye Liu et al.   CNS Neuroscience & Therapeutics

Alpha-chymotrypcin ameliorates neuroinflammation and apoptosis characterizing Alzheimer's disease-induced in ovarictomized rats

(2012) Samiha M. Abd El Dayem et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes

(2012) Jacob M. Basak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPARs: Fatty acid sensors controlling metabolism

(2012) Lars la Cour Poulsen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Blood–brain barrier P-glycoprotein function in Alzheimer's disease

(2011) Daniëlle M. E. van Assema et al.   BRAIN

Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice

(2011) Michal Aharoni-Simon et al.   LABORATORY INVESTIGATION

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

(2011) Yi Yang et al.   STROKE

Permeability of Endothelial and Astrocyte Cocultures: In Vitro Blood–Brain Barrier Models for Drug Delivery Studies

(2010) Guanglei Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Silver Nanoparticles Crossing Through and Distribution in the Blood-Brain Barrier In Vitro

(2010) Jinglong Tang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Silver Nanoparticle Induced Blood-Brain Barrier Inflammation and Increased Permeability in Primary Rat Brain Microvessel Endothelial Cells

(2010) William J. Trickler et al.   TOXICOLOGICAL SCIENCES

Clearance of Amyloid-β Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimers Disease

(2009) R. Deane et al.   CNS & Neurological Disorders-Drug Targets

Palmitic acid mediates hypothalamic insulin resistance by altering PKC-θ subcellular localization in rodents

(2009) Stephen C. Benoit et al.   JOURNAL OF CLINICAL INVESTIGATION

Distribution, Translocation and Accumulation of Silver Nanoparticles in Rats

(2009) Jinglong Tang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

PVP-coated silver nanoparticles and silver ions induce reactive oxygen species, apoptosis and necrosis in THP-1 monocytes

(2009) Rasmus Foldbjerg et al.   TOXICOLOGY LETTERS

The Low Density Lipoprotein Receptor-related Protein 1 Mediates Uptake of Amyloid β Peptides in anin VitroModel of the Blood-Brain Barrier Cells

(2008) Kaoru Yamada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase Transfer Surfactant-Aided Trypsin Digestion for Membrane Proteome Analysis

(2008) Takeshi Masuda et al.   JOURNAL OF PROTEOME RESEARCH

Beta‐site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease

(2008) Harald Hampel et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION