Nitrosative Stress Induces Peroxiredoxin 1 Ubiquitination During Ischemic Insult via E6AP Activation in Endothelial Cells Both In Vitro and In Vivo

Overexpression of Peroxiredoxin 4 Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice

(2012) Xin Guo et al.   ANTIOXIDANTS & REDOX SIGNALING

Transgenic Overexpression of Peroxiredoxin-2 Attenuates Ischemic Neuronal Injury Via Suppression of a Redox-Sensitive Pro-Death Signaling Pathway

(2012) Yu Gan et al.   ANTIOXIDANTS & REDOX SIGNALING

The γ-Secretase Blocker DAPT Reduces the Permeability of the Blood-Brain Barrier by Decreasing the Ubiquitination and Degradation of Occludin During Permanent Brain Ischemia

(2012) Gen-Sheng Zhang et al.   CNS Neuroscience & Therapeutics

Targeting Nitrosative Stress for Neurovascular Protection: New Implications in Brain Diseases

(2012) Rong-Rong Tao et al.   CURRENT DRUG TARGETS

Dithiol-based Compounds Maintain Expression of Antioxidant Protein Peroxiredoxin 1 That Counteracts Toxicity of Mutant Huntingtin

(2012) Andrea Pitts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prdx1 deficiency in mice promotes tissue specific loss of heterozygosity mediated by deficiency in DNA repair and increased oxidative stress

(2012) Vamsi Rani et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Peroxiredoxin 1 Stimulates Endothelial Cell Expression of VEGF via TLR4 Dependent Activation of HIF-1α

(2012) Jonah R. Riddell et al.   PLoS One

Peroxides and Peroxidases in the Endoplasmic Reticulum: Integrating Redox Homeostasis and Oxidative Folding

(2011) Taichi Kakihana et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein Glutathionylation in the Regulation of Peroxiredoxins: A Family of Thiol-Specific Peroxidases That Function As Antioxidants, Molecular Chaperones, and Signal Modulators

(2011) Ho Zoon Chae et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells

(2011) Feng Han et al.   JOURNAL OF PINEAL RESEARCH

The Neurovascular Link in Health and Disease: Molecular Mechanisms and Therapeutic Implications

(2011) Annelies Quaegebeur et al.   NEURON

 -Synuclein fate is determined by USP9X-regulated monoubiquitination

(2011) R. Rott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The neurovascular unit, matrix proteases, and innate inflammation

(2010) Gregory J. Del Zoppo   Annals of the New York Academy of Sciences

S-Nitrosylation of Critical Protein Thiols Mediates Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative Diseases

(2010) Tomohiro Nakamura et al.   ANTIOXIDANTS & REDOX SIGNALING

Peroxiredoxin 6: A Bifunctional Enzyme with Glutathione Peroxidase and Phospholipase A2 Activities

(2010) Aron B. Fisher   ANTIOXIDANTS & REDOX SIGNALING

Comparison of glutathione peroxidase 1 and peroxiredoxin 6 in protection against oxidative stress in the mouse lung

(2010) Geng Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

E6AP ubiquitin ligase mediates ubiquitin-dependent degradation of peroxiredoxin 1

(2010) Junichi Nasu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Melatonin ameliorates ischemic-like injury-evoked nitrosative stress: Involvement of HtrA2/PED pathways in endothelial cells

(2010) Feng Han et al.   JOURNAL OF PINEAL RESEARCH

Brain Endothelial Cell Death: Modes, Signaling Pathways, and Relevance to Neural Development, Homeostasis, and Disease

(2010) Maria Teresa Rizzo et al.   MOLECULAR NEUROBIOLOGY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes: Blood-Brain Barrier Safeguards against Neurodegeneration?

(2010) Annelies Quaegebeur et al.   NEURON

The induction of reactive oxygen species and loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells

(2010) Qi-bing Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Redox Proteomic Analysis of Carbonylated Brain Proteins in Mild Cognitive Impairment and Early Alzheimer's Disease

(2009) Rukhsana Sultana et al.   ANTIOXIDANTS & REDOX SIGNALING

Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity

(2009) M Brunet Simioni et al.   ONCOGENE

Endoplasmic reticulum stress in the absence of calnexin

(2008) Helen Coe et al.   CELL STRESS & CHAPERONES

Peroxiredoxin1 Prevents Excessive Endothelial Activation and Early Atherosclerosis

(2008) Janka Kisucka et al.   CIRCULATION RESEARCH

A novel function of peroxiredoxin 1 (Prx-1) in apoptosis signal-regulating kinase 1 (ASK1)-mediated signaling pathway

(2008) So Yong Kim et al.   FEBS LETTERS

Protective effects of peroxiredoxin-1 at the injured blood–brain barrier

(2008) Gerty Schreibelt et al.   FREE RADICAL BIOLOGY AND MEDICINE

Accumulation of beta-amyloid in the brain microvessels accompanies increased hyperphosphorylated tau proteins following microsphere embolism in aged rats

(2008) F. Han et al.   NEUROSCIENCE

Chemistry and Antihypertensive Effects of Tempol and Other Nitroxides

(2008) C. S. Wilcox et al.   PHARMACOLOGICAL REVIEWS