Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants
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Title
Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants
Authors
Keywords
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Journal
ARCHIVES OF TOXICOLOGY
Volume 94, Issue 9, Pages 3105-3123
Publisher
Springer Science and Business Media LLC
Online
2020-06-30
DOI
10.1007/s00204-020-02826-y
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Note: Only part of the references are listed.- The Contribution of Iron to Protein Aggregation Disorders in the Central Nervous System
- (2019) Karina Joppe et al. Frontiers in Neuroscience
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- (2018) Georgina Harris et al. ARCHIVES OF TOXICOLOGY
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- (2018) Sílvia Chaves et al. CURRENT MEDICINAL CHEMISTRY
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- (2018) Natesh Singh et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Christine Kaindlstorfer et al. JOURNAL OF ALZHEIMERS DISEASE
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- (2018) Simon Gutbier et al. CELL DEATH AND DIFFERENTIATION
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- (2017) Raphaël Gillet et al. INORGANIC CHEMISTRY
- Tipping Points and Endogenous Determinants of Nigrostriatal Degeneration by MPTP
- (2017) Stefan Schildknecht et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Protective efficacy of phosphodiesterase-1 inhibition against alpha-synuclein toxicity revealed by compound screening in LUHMES cells
- (2017) Matthias Höllerhage et al. Scientific Reports
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- (2017) David Dickens et al. Scientific Reports
- Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson’s disease
- (2017) Antonio Martin-Bastida et al. Scientific Reports
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- (2016) Petr Dusek et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
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- (2016) Saravanan S. Karuppagounder et al. Science Translational Medicine
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- (2015) Stefan Schildknecht et al. ANTIOXIDANTS & REDOX SIGNALING
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- Prevention of the degeneration of human dopaminergic neurons in an astrocyte co-culture system allowing endogenous drug metabolism
- (2015) Liudmila Efremova et al. BRITISH JOURNAL OF PHARMACOLOGY
- Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators
- (2015) David G. Workman et al. Metallomics
- Regulation of Ferroptotic Cancer Cell Death by GPX4
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- The role of iron in brain ageing and neurodegenerative disorders
- (2014) Roberta J Ward et al. LANCET NEUROLOGY
- Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+
- (2014) A K Krug et al. Cell Death & Disease
- Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease
- (2013) David Devos et al. ANTIOXIDANTS & REDOX SIGNALING
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- Oxidative and nitrative alpha-synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies
- (2013) Stefan Schildknecht et al. JOURNAL OF NEUROCHEMISTRY
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Design of iron chelators with therapeutic application
- (2012) Tao Zhou et al. DALTON TRANSACTIONS
- α-Synuclein expression is modulated at the translational level by iron
- (2012) Fabia Febbraro et al. NEUROREPORT
- Ironing out neurodegeneration: Iron chelation for neuroprotection
- (2011) Joshua L. Dunaief FREE RADICAL BIOLOGY AND MEDICINE
- Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line
- (2011) Diana Scholz et al. JOURNAL OF NEUROCHEMISTRY
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- (2011) Dominik Pöltl et al. NEUROTOXICOLOGY
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- (2010) Stefan Schildknecht et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proteasome and oxidative phoshorylation changes may explain why aging is a risk factor for neurodegenerative disorders
- (2010) Claus Zabel et al. Journal of Proteomics
- Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle
- (2009) Kristen A Malkus et al. Molecular Neurodegeneration
- The Parkinson chimera
- (2009) A. J. Lees NEUROLOGY
- Effects of Deferoxamine on Intracerebral Hemorrhage-Induced Brain Injury in Aged Rats
- (2009) Masanobu Okauchi et al. STROKE
- Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells
- (2009) Stefan Schildknecht et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts
- (2009) Joshua Z Levin et al. GENOME BIOLOGY
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- (2008) Shannon L. Rhodes et al. NEUROBIOLOGY OF DISEASE
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