Prevention of neuronal apoptosis by astrocytes through thiol-mediated stress response modulation and accelerated recovery from proteotoxic stress

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

(2017) Pedro M. Quirós et al.   JOURNAL OF CELL BIOLOGY

N -Acetyl-l-Cysteine Protects Astrocytes against Proteotoxicity without Recourse to Glutathione

(2017) Amanda M. Gleixner et al.   MOLECULAR PHARMACOLOGY

Sirtuin 2 enhances dopaminergic differentiation via the AKT/GSK-3β/β-catenin pathway

(2017) Éva M. Szegő et al.   NEUROBIOLOGY OF AGING

Stage-specific metabolic features of differentiating neurons: Implications for toxicant sensitivity

(2017) Johannes Delp et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tipping Points and Endogenous Determinants of Nigrostriatal Degeneration by MPTP

(2017) Stefan Schildknecht et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Tert-buthylhydroquinone pre-conditioning exerts dual effects in old female rats exposed to 3-nitropropionic acid

(2017) Alejandro Silva-Palacios et al.   Redox Biology

TCF11/Nrf1-Mediated Induction of Proteasome Expression Prevents Cytotoxicity by Rotenone

(2016) Franziska Sotzny et al.   ANTIOXIDANTS & REDOX SIGNALING

Effects of DDIT4 in Methamphetamine-Induced Autophagy and Apoptosis in Dopaminergic Neurons

(2016) Bing Li et al.   MOLECULAR NEUROBIOLOGY

Quantification of Metabolic Rearrangements During Neural Stem Cells Differentiation into Astrocytes by Metabolic Flux Analysis

(2016) João V. Sá et al.   NEUROCHEMICAL RESEARCH

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease

(2016) Roberto Di Maio et al.   Science Translational Medicine

Conversion of Nonproliferating Astrocytes into Neurogenic Neural Stem Cells: Control by FGF2 and Interferon-γ

(2016) Susanne Kleiderman et al.   STEM CELLS

Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells

(2016) K K Starheim et al.   Blood Cancer Journal

Prevention of the degeneration of human dopaminergic neurons in an astrocyte co-culture system allowing endogenous drug metabolism

(2015) Liudmila Efremova et al.   BRITISH JOURNAL OF PHARMACOLOGY

Functional and phenotypic differences of pure populations of stem cell-derived astrocytes and neuronal precursor cells

(2015) Susanne Kleiderman et al.   GLIA

Neuroprotective effects of urate are mediated by augmenting astrocytic glutathione synthesis and release

(2015) Rachit Bakshi et al.   NEUROBIOLOGY OF DISEASE

Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives

(2014) Anthony H V Schapira et al.   LANCET

Coordinated regulation of protein synthesis and degradation by mTORC1

(2014) Yinan Zhang et al.   NATURE

Parkinson’s disease: animal models and dopaminergic cell vulnerability

(2014) Javier Blesa et al.   Frontiers in Neuroanatomy

Parkinson disease: from pathology to molecular disease mechanisms

(2013) David T. Dexter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress-induced posttranslational modifications of alpha-synuclein: Specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity

(2013) Wei Xiang et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Antioxidant and bioenergetic coupling between neurons and astrocytes

(2012) Seila Fernandez-Fernandez et al.   BIOCHEMICAL JOURNAL

Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration

(2012) Kunal Gupta et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Failure of Amino Acid Homeostasis Causes Cell Death following Proteasome Inhibition

(2012) Amila Suraweera et al.   MOLECULAR CELL

Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms

(2011) K Gupta et al.   CELL DEATH AND DIFFERENTIATION

GFAP-independent inflammatory competence and trophic functions of astrocytes generated from murine embryonic stem cells

(2011) Philipp B. Kuegler et al.   GLIA

Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line

(2011) Diana Scholz et al.   JOURNAL OF NEUROCHEMISTRY

Excitotoxicity Triggered by Neurobasal Culture Medium

(2011) Joshua Hogins et al.   PLoS One

Astrocyte–neuron metabolic relationships: for better and for worse

(2011) Igor Allaman et al.   TRENDS IN NEUROSCIENCES

Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells

(2010) Senthil K. Radhakrishnan et al.   MOLECULAR CELL

Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop

(2010) Janos Steffen et al.   MOLECULAR CELL

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

(2010) K. F. Bell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway

(2010) R. E. Haskew-Layton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The MitoPark Mouse – An animal model of Parkinson's disease with impaired respiratory chain function in dopamine neurons

(2009) Mats I. Ekstrand et al.   PARKINSONISM & RELATED DISORDERS

The undertow of sulfur metabolism on glutamatergic neurotransmission

(2008) Ruma Banerjee et al.   TRENDS IN BIOCHEMICAL SCIENCES

Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1

(2007) Takumi Satoh et al.   JOURNAL OF NEUROCHEMISTRY