Integrated Process for Capture and Purification of Virus-Like Particles: Enhancing Process Performance by Cross-Flow Filtration

Accelerating Biologics Manufacturing by Modeling: Process Integration of Precipitation in mAb Downstream Processing

(2020) Lara Julia Lohmann et al.   Processes

Assembly and Characterization of HBc Derived Virus-like Particles with Magnetic Core

(2019) Jakub Rybka et al.   Nanomaterials

Process Monitoring of Virus‐like Particle Reassembly by Diafiltration with UV/Vis Spectroscopy and Light Scattering

(2019) Matthias Rüdt et al.   BIOTECHNOLOGY AND BIOENGINEERING

Precipitation of complex antibody solutions: influence of contaminant composition and cell culture medium on the precipitation behavior

(2019) Steffen Großhans et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Membrane‐based approach for the downstream processing of influenza virus‐like particles

(2019) Sofia B. Carvalho et al.   Biotechnology Journal

Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

(2019) Mona O. Mohsen et al.   Journal for ImmunoTherapy of Cancer

Continuous Precipitation for Monoclonal Antibody Capture Using Countercurrent Washing by Microfiltration

(2019) Zhao Li et al.   BIOTECHNOLOGY PROGRESS

Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine

(2019) Mona O. Mohsen et al.   Frontiers in Immunology

Salt-enhanced permeabilization for monoclonal antibody precipitation and purification in a tubular reactor with a depth filtration membrane with advanced chromatin extraction

(2019) Wenshuai Liu et al.   BIOCHEMICAL ENGINEERING JOURNAL

Establishment of a yeast-based VLP platform for antigen presentation

(2018) David Wetzel et al.   Microbial Cell Factories

Virus-like particle display of HER2 induces potent anti-cancer responses

(2018) Arianna Palladini et al.   OncoImmunology

Separation of virus-like particles and extracellular vesicles by flow-through and heparin affinity chromatography

(2018) Katrin Reiter et al.   JOURNAL OF CHROMATOGRAPHY A

Precipitation as an Enabling Technology for the Intensification of Biopharmaceutical Manufacture

(2018) Michael Martinez et al.   TRENDS IN BIOTECHNOLOGY

A Virus-Like-Particle immunotherapy targeting Epitope-Specific anti-xCT expressed on cancer stem cell inhibits the progression of metastatic cancer in vivo

(2017) Elisabetta Bolli et al.   OncoImmunology

Prevention of cervical cancer: journey to develop the first human papillomavirus virus-like particle vaccine and the next generation vaccine

(2016) Janine T Bryan et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A simple and efficient purification platform for monoclonal antibody production based on chromatin-directed cell culture clarification integrated with precipitation and void-exclusion anion exchange chromatography

(2016) Quan Chen et al.   JOURNAL OF BIOTECHNOLOGY

Modeling and simulation of anion-exchange membrane chromatography for purification of Sf9 insect cell-derived virus-like particles

(2016) Christopher Ladd Effio et al.   JOURNAL OF CHROMATOGRAPHY A

Scalable chromatography-based purification of virus-like particle carrier for epitope based influenza A vaccine produced in Escherichia coli

(2016) Priscillia Lagoutte et al.   JOURNAL OF VIROLOGICAL METHODS

Characterizing Enterovirus 71 and Coxsackievirus A16 virus-like particles production in insect cells

(2016) Balaji Somasundaram et al.   METHODS

Influence of the concentration and molecular weight of polyethylene glycol on the structure and permeability of polysulfone hollow fiber membranes

(2016) T. V. Plisko et al.   PETROLEUM CHEMISTRY

Continuous polyethylene glycol precipitation of recombinant antibodies: Sequential precipitation and resolubilization

(2016) Nikolaus Hammerschmidt et al.   PROCESS BIOCHEMISTRY

Scalable Production of HPV16 L1 Protein and VLPs from Tobacco Leaves

(2016) Maryam Zahin et al.   PLoS One

Next generation vaccines and vectors: Designing downstream processes for recombinant protein-based virus-like particles

(2015) Christopher Ladd Effio et al.   Biotechnology Journal

Evaluation of methods to purify virus-like particles for metagenomic sequencing of intestinal viromes

(2015) Manuel Kleiner et al.   BMC GENOMICS

Genetics and Vaccines in the Era of Personalized Medicine

(2015) John Castiblanco et al.   CURRENT GENOMICS

Enterovirus71 virus-like particles produced from insect cells and purified by multistep chromatography elicit strong humoral immune responses in mice

(2015) D. Zhao et al.   JOURNAL OF APPLIED MICROBIOLOGY

In situ vaccination with cowpea mosaic virus nanoparticles suppresses metastatic cancer

(2015) P. H. Lizotte et al.   Nature Nanotechnology

Assembly and Release of Hepatitis B Virus

(2015) Lisa Selzer et al.   Cold Spring Harbor Perspectives in Medicine

Downstream processing and chromatography based analytical methods for production of vaccines, gene therapy vectors, and bacteriophages

(2015) Petra Kramberger et al.   Human Vaccines & Immunotherapeutics

Next generation vaccines and vectors: Designing downstream processes for recombinant protein-based virus-like particles

(2015) Christopher Ladd Effio et al.   Biotechnology Journal

The contribution of vaccination to global health: past, present and future

(2014) B. Greenwood   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Concentration and purification of enterovirus 71 using a weak anion-exchange monolithic column

(2014) Ashok Kattur Venkatachalam et al.   Virology Journal

New developments in cancer vaccines

(2013) Luigi Buonaguro et al.   Expert Review of Vaccines

HLA ligandome tumor antigen discovery for personalized vaccine approach

(2013) Hans-Georg Rammensee et al.   Expert Review of Vaccines

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8+T-cell responses in melanoma patients

(2012) Simone M. Goldinger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Purification of norovirus-like particles (VLPs) by ion exchange chromatography

(2012) Tiia Koho et al.   JOURNAL OF VIROLOGICAL METHODS

Construction and Characterization of Virus-Like Particles: A Review

(2012) Andris Zeltins   MOLECULAR BIOTECHNOLOGY

Disassembly and reassembly improves morphology and thermal stability of human papillomavirus type 16 virus-like particles

(2012) Qinjian Zhao et al.   Nanomedicine-Nanotechnology Biology and Medicine

Highly Specific Auto-Antibodies against Claudin-18 Isoform 2 Induced by a Chimeric HBcAg Virus-Like Particle Vaccine Kill Tumor Cells and Inhibit the Growth of Lung Metastases

(2011) Thorsten Klamp et al.   CANCER RESEARCH

Protein precipitation by polyethylene glycol: A generalized model based on hydrodynamic radius

(2011) Siow-Leng Sim et al.   JOURNAL OF BIOTECHNOLOGY

A single-use purification process for the production of a monoclonal antibody produced in a PER.C6 human cell line

(2010) Michael Kuczewski et al.   Biotechnology Journal

Enterovirus 71 virus-like particle vaccine: Improved production conditions for enhanced yield

(2010) Cheng-Yu Chung et al.   VACCINE

Multiepitope peptide-loaded virus-like particles as a vaccine against hepatitis B virus-related hepatocellular carcinoma

(2009) Fei-Xiang Ding et al.   HEPATOLOGY

One-step chromatographic purification of human papillomavirus type 16 L1 protein from Saccharomyces cerevisiae

(2009) Hyoung Jin Kim et al.   PROTEIN EXPRESSION AND PURIFICATION

Selective precipitation-assisted recovery of immunoglobulins from bovine serum using controlled-fouling crossflow membrane microfiltration

(2008) Adith Venkiteshwaran et al.   BIOTECHNOLOGY AND BIOENGINEERING