Downstream processing and chromatography based analytical methods for production of vaccines, gene therapy vectors, and bacteriophages

Particle quantification of influenza viruses by high performance liquid chromatography

(2015) Julia Transfiguracion et al.   VACCINE

Improving stability of virus-like particles by ion-exchange chromatographic supports with large pore size: Advantages of gigaporous media beyond enhanced binding capacity

(2014) Mengran Yu et al.   JOURNAL OF CHROMATOGRAPHY A

Development and application of a reversed-phase high-performance liquid chromatographic method for quantitation and characterization of a Chikungunya virus-like particle vaccine

(2014) Anastasija Shytuhina et al.   JOURNAL OF CHROMATOGRAPHY A

Purification of Vero cell derived live replication deficient influenza A and B virus by ion exchange monolith chromatography

(2014) Marko Banjac et al.   VACCINE

Purification of infective baculoviruses by monoliths

(2013) Petra Gerster et al.   JOURNAL OF CHROMATOGRAPHY A

Protein and virus-like particle adsorption on perfusion chromatography media

(2013) Yige Wu et al.   JOURNAL OF CHROMATOGRAPHY A

Simultaneous quantification of the viral antigens hemagglutinin and neuraminidase in influenza vaccines by LC–MSE

(2012) Marybeth C. Creskey et al.   VACCINE

Monolithic ion exchange chromatographic methods for virus purification

(2012) Hanna M. Oksanen et al.   VIROLOGY

CIM® monolithic anion-exchange chromatography as a useful alternative to CsCl gradient purification of bacteriophage particles

(2012) Evelien M. Adriaenssens et al.   VIROLOGY

Downstream Processing of Lentiviral Vectors: Releasing Bottlenecks

(2012) Vanessa Bandeira et al.   Human Gene Therapy Methods

Chromatography Purification of Canine Adenoviral Vectors

(2012) María Mercedes Segura et al.   Human Gene Therapy Methods

Analysis of Particle Content of Recombinant Adeno-Associated Virus Serotype 8 Vectors by Ion-Exchange Chromatography

(2012) Martin Lock et al.   Human Gene Therapy Methods

Production and purification of lentiviral vectors generated in 293T suspension cells with baculoviral vectors

(2011) H P Lesch et al.   GENE THERAPY

Phase 2 Clinical Trial of a Recombinant Adeno-Associated Viral Vector Expressing α1-Antitrypsin: Interim Results

(2011) Terence R. Flotte et al.   HUMAN GENE THERAPY

Purification of recombinant adenovirus type 3 dodecahedric virus-like particles for biomedical applications using short monolithic columns

(2011) Lidija Urbas et al.   JOURNAL OF CHROMATOGRAPHY A

Concentration and purification of rubella virus using monolithic chromatographic support

(2011) Dubravko Forcic et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A monolith purification process for virus-like particles from yeast homogenate

(2011) Claire S. Burden et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Purification and concentration of non-infectious West Nile virus-like particles and infectious virions using a pseudo-affinity Cellufine Sulfate column

(2011) Naohiro Ohtaki et al.   JOURNAL OF VIROLOGICAL METHODS

Optimization and qualification of a quantitative reversed-phase HPLC method for hemagglutinin in influenza preparations and its comparative evaluation with biochemical assays

(2011) Barry Lorbetskie et al.   VACCINE

Purification of porcine reproductive and respiratory syndrome virus from cell culture using ultrafiltration and heparin affinity chromatography

(2010) Jianzhong Hu et al.   JOURNAL OF CHROMATOGRAPHY A

Reversed phase monolithic analytical columns for the determination of HA1 subunit of influenza virus haemagglutinin

(2010) Lidija Urbas et al.   JOURNAL OF CHROMATOGRAPHY A

Characterisation of methacrylate monoliths for bacteriophage purification

(2010) Franc Smrekar et al.   JOURNAL OF CHROMATOGRAPHY A

Development and validation of a HPLC method for the quantification of baculovirus particles

(2010) Julia Transfiguracion et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Purification of the Staphylococcus aureus bacteriophages VDX-10 on methacrylate monoliths

(2010) Petra Kramberger et al.   JOURNAL OF VIROLOGICAL METHODS

Purification of recombinant baculoviruses for gene therapy using membrane processes

(2009) T Vicente et al.   GENE THERAPY

Purification of cell culture-derived influenza virus A/Puerto Rico/8/34 by membrane-based immobilized metal affinity chromatography

(2009) Lars Opitz et al.   JOURNAL OF VIROLOGICAL METHODS

Towards purification of adenoviral vectors based on membrane technology

(2008) Cristina Peixoto et al.   BIOTECHNOLOGY PROGRESS

Rapid high-performance liquid chromatographic analysis of adenovirus type 5 particles with a prototype anion-exchange analytical monolith column

(2008) Robert J. Whitfield et al.   JOURNAL OF CHROMATOGRAPHY A

Concentrating rotaviruses from water samples using monolithic chromatographic supports

(2008) Ion Gutiérrez-Aguirre et al.   JOURNAL OF CHROMATOGRAPHY A

Rapid and reliable quantification of reovirus type 3 by high performance liquid chromatography during manufacturing of Reolysin®

(2008) Julia Transfiguracion et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

HPLC-based quantification of haemagglutinin in the production of egg- and MDCK cell-derived influenza virus seasonal and pandemic vaccines

(2008) J.C. Kapteyn et al.   VACCINE

Purification and concentration of bacteriophage T4 using monolithic chromatographic supports

(2007) F. Smrekar et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Anion-exchange membrane chromatography for purification of rotavirus-like particles

(2007) Tiago Vicente et al.   JOURNAL OF MEMBRANE SCIENCE

Purification of human respiratory syncytial virus by ultracentrifugation in iodixanol density gradient

(2007) E. Gias et al.   JOURNAL OF VIROLOGICAL METHODS