The obesity-induced adipokine sST2 exacerbates adipose Treg and ILC2 depletion and promotes insulin resistance

Epithelial cell–derived cytokines: more than just signaling the alarm

(2019) Florence Roan et al.   JOURNAL OF CLINICAL INVESTIGATION

Stromal cells maintain immune cell homeostasis in adipose tissue via production of interleukin-33

(2019) T. Mahlakõiv et al.   Science Immunology

Obesity, Fat Mass and Immune System: Role for Leptin

(2018) Vera Francisco et al.   Frontiers in Physiology

The long noncoding RNA Blnc1 orchestrates homeostatic adipose tissue remodeling to preserve metabolic health

(2018) Xu-Yun Zhao et al.   Molecular Metabolism

Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis

(2017) Siming Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases

(2017) Brad Griesenauer et al.   Frontiers in Immunology

Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders

(2017) Zhimin Chen et al.   Molecular Metabolism

Perinatal Licensing of Thermogenesis by IL-33 and ST2

(2016) Justin I. Odegaard et al.   CELL

Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk

(2016) Jennifer H. Stern et al.   Cell Metabolism

Distribution and clinical association of plasma soluble ST2 during the development of type 2 diabetes

(2016) Ya-Hui Lin et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

IL-33-driven ILC2/eosinophil axis in fat is induced by sympathetic tone and suppressed by obesity

(2016) Xiaofeng Ding et al.   JOURNAL OF ENDOCRINOLOGY

Adipose Tissue Dendritic Cells Are Independent Contributors to Obesity-Induced Inflammation and Insulin Resistance

(2016) Kae Won Cho et al.   JOURNAL OF IMMUNOLOGY

Adiponectin: a versatile player of innate immunity

(2016) Yan Luo et al.   Journal of Molecular Cell Biology

The Ubiquitination of NF-κB Subunits in the Control of Transcription

(2016) Patricia Collins et al.   Cells

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

(2015) Min-Woo Lee et al.   CELL

Antigen- and Cytokine-Driven Accumulation of Regulatory T Cells in Visceral Adipose Tissue of Lean Mice

(2015) Dmitriy Kolodin et al.   Cell Metabolism

An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers

(2015) Hideaki Morita et al.   IMMUNITY

Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation

(2015) Ari B. Molofsky et al.   IMMUNITY

The cell biology of fat expansion

(2015) Joseph M. Rutkowski et al.   JOURNAL OF CELL BIOLOGY

IL-33 Reverses an Obesity-Induced Deficit in Visceral Adipose Tissue ST2+T Regulatory Cells and Ameliorates Adipose Tissue Inflammation and Insulin Resistance

(2015) Jonathan M. Han et al.   JOURNAL OF IMMUNOLOGY

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

(2015) Ajithkumar Vasanthakumar et al.   NATURE IMMUNOLOGY

Macrophages and the Regulation of Adipose Tissue Remodeling

(2014) Gabriel Martinez-Santibañez et al.   Annual Review of Nutrition

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

(2014) Jonathan R. Brestoff et al.   NATURE

The alarmin IL-33 promotes regulatory T-cell function in the intestine

(2014) Chris Schiering et al.   NATURE

The brown fat–enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis

(2014) Guo-Xiao Wang et al.   NATURE MEDICINE

Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration

(2013) Yun-Hee Lee et al.   Cell Metabolism

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

(2013) Ari B. Molofsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autophagy Deficiency by Hepatic FIP200 Deletion Uncouples Steatosis From Liver Injury in NAFLD

(2013) Di Ma et al.   MOLECULAR ENDOCRINOLOGY

Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

(2012) Marsha Wills-Karp et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endogenous IL-33 Is Highly Expressed in Mouse Epithelial Barrier Tissues, Lymphoid Organs, Brain, Embryos, and Inflamed Tissues: In Situ Analysis Using a Novel Il-33-LacZ Gene Trap Reporter Strain

(2012) M. Pichery et al.   JOURNAL OF IMMUNOLOGY

Interleukin-33 Induces Protective Effects in Adipose Tissue Inflammation During Obesity in Mice

(2010) Ashley M. Miller et al.   CIRCULATION RESEARCH

Mast cells, macrophages, and crown-like structures distinguish subcutaneous from visceral fat in mice

(2010) Mehmet M. Altintas et al.   JOURNAL OF LIPID RESEARCH

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

(2009) Jian Liu et al.   NATURE MEDICINE

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

Genome-wide Coactivation Analysis of PGC-1α Identifies BAF60a as a Regulator of Hepatic Lipid Metabolism

(2008) Siming Li et al.   Cell Metabolism

The Zinc Finger Transcription Factor Zbtb7b Represses CD8-Lineage Gene Expression in Peripheral CD4+ T Cells

(2008) Lie Wang et al.   IMMUNITY

IL-33 exacerbates antigen-induced arthritis by activating mast cells

(2008) D. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA