The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV

(2014) M Grusdat et al.   CELL DEATH AND DIFFERENTIATION

Blockade of IL-33/ST2 ameliorates airway inflammation in a murine model of allergic asthma

(2014) Hea Yon Lee et al.   EXPERIMENTAL LUNG RESEARCH

Role of interleukin 33 in respiratory allergy and asthma

(2014) Heidi Makrinioti et al.   Lancet Respiratory Medicine

Organ-Specific and Memory Treg Cells: Specificity, Development, Function, and Maintenance

(2014) Iris K. Gratz et al.   Frontiers in Immunology

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Development and Maintenance of Regulatory T cells

(2013) Naganari Ohkura et al.   IMMUNITY

Control of inflammation by integration of environmental cues by regulatory T cells

(2013) Ashutosh Chaudhry et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

(2013) Ari B. Molofsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets

(2013) Kate S. Smigiel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immune Regulation in Obesity-Associated Adipose Inflammation

(2013) J. M. Han et al.   JOURNAL OF IMMUNOLOGY

The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells

(2013) Kevin Man et al.   NATURE IMMUNOLOGY

Regulatory T cells in nonlymphoid tissues

(2013) Dalia Burzyn et al.   NATURE IMMUNOLOGY

TH2, allergy and group 2 innate lymphoid cells

(2013) Paula Licona-Limón et al.   NATURE IMMUNOLOGY

Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells

(2013) Wim Pierson et al.   NATURE IMMUNOLOGY

Special aspects of interleukin-33 and the IL-33 receptor complex

(2013) Michael U. Martin   SEMINARS IN IMMUNOLOGY

The interleukin-1 receptor family

(2013) Diana Boraschi et al.   SEMINARS IN IMMUNOLOGY

A Validated Regulatory Network for Th17 Cell Specification

(2012) Maria Ciofani et al.   CELL

The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology

(2012) Aisling O’Hara Hall et al.   IMMUNITY

Severe obesity increases adipose tissue expression of interleukin-33 and its receptor ST2, both predominantly detectable in endothelial cells of human adipose tissue

(2012) M Zeyda et al.   INTERNATIONAL JOURNAL OF OBESITY

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+T reg cells

(2012) Jonathan M. Weiss et al.   JOURNAL OF EXPERIMENTAL MEDICINE

BATF–JUN is critical for IRF4-mediated transcription in T cells

(2012) Peng Li et al.   NATURE

The Alarmin Interleukin-33 Drives Protective Antiviral CD8+ T Cell Responses

(2012) W. V. Bonilla et al.   SCIENCE

A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes

(2012) E. Glasmacher et al.   SCIENCE

The Inhibitory Receptor PD-1 Regulates IgA Selection and Bacterial Composition in the Gut

(2012) S. Kawamoto et al.   SCIENCE

Differentiation and function of Foxp3+ effector regulatory T cells

(2012) Erika Cretney et al.   TRENDS IN IMMUNOLOGY

An Essential Role of the Transcription Factor GATA-3 for the Function of Regulatory T Cells

(2011) Yunqi Wang et al.   IMMUNITY

GATA3 controls Foxp3+ regulatory T cell fate during inflammation in mice

(2011) Elizabeth A. Wohlfert et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-33 Expands Suppressive CD11b+ Gr-1int and Regulatory T Cells, including ST2L+ Foxp3+ Cells, and Mediates Regulatory T Cell-Dependent Promotion of Cardiac Allograft Survival

(2011) H. R. Turnquist et al.   JOURNAL OF IMMUNOLOGY

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

(2011) Erika Cretney et al.   NATURE IMMUNOLOGY

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

Interleukin-33 Induces Protective Effects in Adipose Tissue Inflammation During Obesity in Mice

(2010) Ashley M. Miller et al.   CIRCULATION RESEARCH

IL-33 is a crucial amplifier of innate rather than acquired immunity

(2010) K. Oboki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic definition of multiple ex vivo regulatory T cell subphenotypes

(2010) M. Feuerer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes

(2009) I. Stuart Wood et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors

(2009) Hyokjoon Kwon et al.   IMMUNITY

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

Foxp3+ regulatory T cells: differentiation, specification, subphenotypes

(2009) Markus Feuerer et al.   NATURE IMMUNOLOGY

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

(2009) L. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The IL-33/ST2 pathway: therapeutic target and novel biomarker

(2008) Rahul Kakkar et al.   NATURE REVIEWS DRUG DISCOVERY

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology