Cellular mechanisms and molecular signaling pathways in stress-induced anxiety, depression, and blood–brain barrier inflammation and leakage

HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia

(2020) Shutian Zhang et al.   Journal of Neuroinflammation

Effects of inflammation on the kynurenine pathway in schizophrenia — a systematic review

(2020) Bruno Pedraz-Petrozzi et al.   Journal of Neuroinflammation

Chronic stress impairs the aquaporin-4-mediated glymphatic transport through glucocorticoid signaling

(2019) Fang Wei et al.   PSYCHOPHARMACOLOGY

Restraint Stress Induced Hyperpermeability and Damage of the Blood-Brain Barrier in the Amygdala of Adult Rats

(2019) Guangming Xu et al.   Frontiers in Molecular Neuroscience

Iba-1-/CD68+ microglia are a prominent feature of age-associated deep subcortical white matter lesions

(2019) Rachel Waller et al.   PLoS One

Role of the PI3K/AKT (mTOR and GSK3β) signalling pathway and photobiomodulation in diabetic wound healing

(2019) Sandy W. Jere et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Depressive symptoms and immune transcriptional profiles in late adolescents

(2019) Jessica J. Chiang et al.   BRAIN BEHAVIOR AND IMMUNITY

Dysfunction of astrocytic connexins 30 and 43 in the medial prefrontal cortex and hippocampus mediates depressive-like behaviours

(2019) Dongming Huang et al.   BEHAVIOURAL BRAIN RESEARCH

Gut Microbiota Disorder, Gut Epithelial and Blood–Brain Barrier Dysfunctions in Etiopathogenesis of Dementia: Molecular Mechanisms and Signaling Pathways

(2019) Menizibeya O. Welcome   NEUROMOLECULAR MEDICINE

Predictable chronic mild stress promotes recovery from LPS-induced depression

(2019) Ruili Dang et al.   Molecular Brain

Psychosis as an adverse effect of monoclonal antibody immunotherapy

(2019) Norah Essali et al.   BRAIN BEHAVIOR AND IMMUNITY

Immune mechanisms of stress susceptibility and resilience: Lessons from animal models

(2019) Mariya Tsyglakova et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Chronic Isolation Stress Affects Subsequent Crowding Stress-Induced Brain Nitric Oxide Synthase (NOS) Isoforms and Hypothalamic-Pituitary-Adrenal (HPA) Axis Responses

(2019) Anna Gądek-Michalska et al.   NEUROTOXICITY RESEARCH

Influence of childhood trauma and brain-derived neurotrophic factor Val66Met polymorphism on posttraumatic stress symptoms and cortical thickness

(2019) Min Jin Jin et al.   Scientific Reports

Astrocyte, a Promising Target for Mood Disorder Interventions

(2019) Xinyi Zhou et al.   Frontiers in Molecular Neuroscience

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

(2019) Amit U. Joshi et al.   NATURE NEUROSCIENCE

Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides

(2019) Arnaud Tanti et al.   NEUROPSYCHOPHARMACOLOGY

Glucocorticoid-Driven NLRP3 Inflammasome Activation in Hippocampal Microglia Mediates Chronic Stress-Induced Depressive-Like Behaviors

(2019) Xiujing Feng et al.   Frontiers in Molecular Neuroscience

Neurovascular Coupling under Chronic Stress Is Modified by Altered GABAergic Interneuron Activity

(2019) Kayoung Han et al.   JOURNAL OF NEUROSCIENCE

Economic Burden of Anxiety Disorders: A Systematic Review and Meta-Analysis

(2019) Alexander Konnopka et al.   PHARMACOECONOMICS

Suppression of NLRP3 inflammasome attenuates stress-induced depression-like behavior in NLGN3-deficient mice

(2018) Ze-Qun Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Elevated Translocator Protein in Anterior Cingulate in Major Depression and a Role for Inflammation in Suicidal Thinking: A Positron Emission Tomography Study

(2018) Sophie E. Holmes et al.   BIOLOGICAL PSYCHIATRY

HMGB1 mediates depressive behavior induced by chronic stress through activating the kynurenine pathway

(2018) Bo Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

Depression and sterile inflammation: Essential role of danger associated molecular patterns

(2018) Tina C. Franklin et al.   BRAIN BEHAVIOR AND IMMUNITY

TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice

(2018) Yuyan Cheng et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammation and the Immune-Kynurenine Pathway in Anxiety Disorders

(2018) Yong-Ku Kim et al.   Current Neuropharmacology

A novel mechanism of depression: role for connexins

(2018) Cong-Yuan Xia et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

A clinical approach to new-onset psychosis associated with immune dysregulation: the concept of autoimmune psychosis

(2018) Souhel Najjar et al.   Journal of Neuroinflammation

Microglial activation mediates chronic mild stress-induced depressive- and anxiety-like behavior in adult rats

(2018) Ya-Lin Wang et al.   Journal of Neuroinflammation

Emerging Concepts in Brain Glucose Metabolic Functions: From Glucose Sensing to How the Sweet Taste of Glucose Regulates Its Own Metabolism in Astrocytes and Neurons

(2018) Menizibeya O. Welcome et al.   NEUROMOLECULAR MEDICINE

Normal aging induces A1-like astrocyte reactivity

(2018) Laura E. Clarke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translocator protein (18 kDa TSPO) binding, a marker of microglia, is reduced in major depression during cognitive-behavioral therapy

(2018) Hua Li et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Kynurenine pathway metabolic balance influences microglia activity: Targeting kynurenine monooxygenase to dampen neuroinflammation

(2018) Allison M. Garrison et al.   PSYCHONEUROENDOCRINOLOGY

Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke

(2018) Stefan Roth et al.   Science Translational Medicine

Prokineticin-2 promotes chemotaxis and alternative A2 reactivity of astrocytes

(2018) Matthew Neal et al.   GLIA

Hippocampal Mrp8/14 signaling plays a critical role in the manifestation of depressive-like behaviors in mice

(2018) Hong Gong et al.   Journal of Neuroinflammation

Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation

(2018) Lige Leng et al.   NEURON

Decoding microglia responses to psychosocial stress reveals blood-brain barrier breakdown that may drive stress susceptibility

(2018) Michael L. Lehmann et al.   Scientific Reports

Cerebrovascular Injury After Serial Exposure to Chronic Stress and Abstinence from Methamphetamine Self-Administration

(2018) Reka Natarajan et al.   Scientific Reports

Real-time in vivo two-photon imaging study reveals decreased cerebro-vascular volume and increased blood-brain barrier permeability in chronically stressed mice

(2018) Sohee Lee et al.   Scientific Reports

Hippocampal CA1 βCaMKII mediates neuroinflammatory responses via COX-2/PGE2 signaling pathways in depression

(2018) Qiqi Song et al.   Journal of Neuroinflammation

Relationship between the anxiety/depression and care burden of the major caregiver of stroke patients

(2018) Ping Hu et al.   MEDICINE

Switching of the Microglial Activation Phenotype Is a Possible Treatment for Depression Disorder

(2018) Lijuan Zhang et al.   Frontiers in Cellular Neuroscience

FCPR16, a novel phosphodiesterase 4 inhibitor, produces an antidepressant-like effect in mice exposed to chronic unpredictable mild stress

(2018) Qiuping Zhong et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Huanglian-Jie-Du-Tang Extract Ameliorates Depression-Like Behaviors through BDNF-TrkB-CREB Pathway in Rats with Chronic Unpredictable Stress

(2017) Yi-Lu Ye et al.   Evidence-based Complementary and Alternative Medicine

Ginsenoside Rg1 alleviates corticosterone-induced dysfunction of gap junctions in astrocytes

(2017) Cong-Yuan Xia et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress

(2017) Dan Zhao et al.   Journal of Neuroinflammation

Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors

(2017) Na Yue et al.   Journal of Neuroinflammation

Depressive-Like Behaviors Are Regulated by NOX1/NADPH Oxidase by Redox Modification of NMDA Receptor 1

(2017) Masakazu Ibi et al.   JOURNAL OF NEUROSCIENCE

Social stress induces neurovascular pathology promoting depression

(2017) Caroline Menard et al.   NATURE NEUROSCIENCE

Prevalence and correlates of DSM-5 major depressive and related disorders in the community

(2017) Caroline L. Vandeleur et al.   PSYCHIATRY RESEARCH

Gap junction channels as potential targets for the treatment of major depressive disorder

(2017) Qian Ren et al.   PSYCHOPHARMACOLOGY

Stressed and Inflamed, Can GSK3 Be Blamed?

(2017) Richard S. Jope et al.   TRENDS IN BIOCHEMICAL SCIENCES

Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease

(2017) Fiona Kerr et al.   PLoS Genetics

Astrocytes at the Hub of the Stress Response: Potential Modulation of Neurogenesis by miRNAs in Astrocyte-Derived Exosomes

(2017) Alejandro Luarte et al.   Stem Cells International

Pelargonidin Modulates Keap1/Nrf2 Pathway Gene Expression and Ameliorates Citrinin-Induced Oxidative Stress in HepG2 Cells

(2017) G. R. Sharath Babu et al.   Frontiers in Pharmacology

NLRP3 inflammasome activation mediates estrogen deficiency-induced depression- and anxiety-like behavior and hippocampal inflammation in mice

(2016) Yongjun Xu et al.   BRAIN BEHAVIOR AND IMMUNITY

Differential effects of stress on microglial cell activation in male and female medial prefrontal cortex

(2016) Justin L. Bollinger et al.   BRAIN BEHAVIOR AND IMMUNITY

At the cross-point of connexins, calcium, and ATP: blocking hemichannels inhibits vasoconstriction of rat small mesenteric arteries

(2016) Mélissa Bol et al.   CARDIOVASCULAR RESEARCH

Thioredoxin-mimetic peptides (TXM) inhibit inflammatory pathways associated with high-glucose and oxidative stress

(2016) Katia Lejnev et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acute restraint stress induces specific changes in nitric oxide production and inflammatory markers in the rat hippocampus and striatum

(2016) Hsiao-Jou Cortina Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Artemisinin inhibits monocyte adhesion to HUVECs through the NF-κB and MAPK pathways in vitro

(2016) YUE WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Stress does not increase blood–brain barrier permeability in mice

(2016) Martin Roszkowski et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Thioredoxin 1 protects astrocytes from oxidative stress by maintaining peroxiredoxin activity

(2016) MENGFEI WANG et al.   Molecular Medicine Reports

Bacterial translocation affects intracellular neuroinflammatory pathways in a depression-like model in rats

(2016) David Martín-Hernández et al.   NEUROPHARMACOLOGY

Danger Signals and Inflammasomes: Stress-Evoked Sterile Inflammation in Mood Disorders

(2016) Monika Fleshner et al.   NEUROPSYCHOPHARMACOLOGY

Density of GFAP-immunoreactive astrocytes is decreased in left hippocampi in major depressive disorder

(2016) J.A. Cobb et al.   NEUROSCIENCE

Astrocyte plasticity induced by emotional stress: A new partner in psychiatric physiopathology?

(2016) Crhistian L. Bender et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness

(2016) Marilia A. Calcia et al.   PSYCHOPHARMACOLOGY

Hypothalamic Astrocytes Respond to Gastric Mucosal Damage Induced by Restraint Water-Immersion Stress in Rat

(2016) Haiji Sun et al.   Frontiers in Behavioral Neuroscience

Occupational Stress: Preventing Suffering, Enhancing Wellbeing

(2016) James Quick et al.   International Journal of Environmental Research and Public Health

Restraint Stress-Induced Morphological Changes at the Blood-Brain Barrier in Adult Rats

(2016) Petra Sántha et al.   Frontiers in Molecular Neuroscience

24-hour-restraint stress induces long-term depressive-like phenotypes in mice

(2016) Xixia Chu et al.   Scientific Reports

Nrf2 regulates ROS production by mitochondria and NADPH oxidase

(2015) Stjepana Kovac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Prevalence of perceived stress and associations to symptoms of exhaustion, depression and anxiety in a working age population seeking primary care - an observational study

(2015) Lilian Wiegner et al.   BMC Family Practice

Aquaporins and blood–brain barrier permeability in early edema development after traumatic brain injury

(2015) Jonas Blixt et al.   BRAIN RESEARCH

NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation

(2015) Y. Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome

(2015) M. D. Weber et al.   JOURNAL OF NEUROSCIENCE

High-mobility group box-1 was released actively and involved in LPS induced depressive-like behavior

(2015) Teng-Yun Wu et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Lithium increases platelet serine-9 phosphorylated GSK-3β levels in drug-free bipolar disorder during depressive episodes

(2015) Rafael T. de Sousa et al.   JOURNAL OF PSYCHIATRIC RESEARCH

The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders

(2015) G.Z. Réus et al.   NEUROSCIENCE

Effects of diet quality on vulnerability to mild subchronic social defeat stress in mice

(2015) Tatsuhiko Goto et al.   NUTRITIONAL NEUROSCIENCE

Activation of the kynurenine pathway is associated with striatal volume in major depressive disorder

(2015) Jonathan Savitz et al.   PSYCHONEUROENDOCRINOLOGY

The Sarcoglycan complex is expressed in the cerebrovascular system and is specifically regulated by astroglial Cx30 channels

(2015) Anne-Cécile Boulay et al.   Frontiers in Cellular Neuroscience

Chronic Stress Decreases Cerebrovascular Responses During Rat Hindlimb Electrical Stimulation

(2015) Sohee Lee et al.   Frontiers in Neuroscience

Treatment-Resistant Major Depression: Rationale for NMDA Receptors as Targets and Nitrous Oxide as Therapy

(2015) Charles F. Zorumski et al.   Frontiers in Psychiatry

Discovery of direct inhibitors of Keap1–Nrf2 protein–protein interaction as potential therapeutic and preventive agents

(2015) Dhulfiqar Ali Abed et al.   Acta Pharmaceutica Sinica B

Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats

(2014) Ying Pan et al.   BRAIN BEHAVIOR AND IMMUNITY

Aquaporin-4 Knockout Exacerbates Corticosterone-Induced Depression by Inhibiting Astrocyte Function and Hippocampal Neurogenesis

(2014) Hui Kong et al.   CNS Neuroscience & Therapeutics

BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals

(2014) Wenling Chen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Toll-like 4 receptor inhibitor TAK-242 decreases neuroinflammation in rat brain frontal cortex after stress

(2014) Iciar Gárate et al.   Journal of Neuroinflammation

Knockdown of Interleukin-1 Receptor Type-1 on Endothelial Cells Attenuated Stress-Induced Neuroinflammation and Prevented Anxiety-Like Behavior

(2014) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

Reduced connexin 43 immunolabeling in the orbitofrontal cortex in alcohol dependence and depression

(2014) José Javier Miguel-Hidalgo et al.   JOURNAL OF PSYCHIATRIC RESEARCH

NMDA receptor dysregulation in chronic state: A possible mechanism underlying depression with BDNF downregulation

(2014) Carol E. Vásquez et al.   NEUROCHEMISTRY INTERNATIONAL

Chronic stress modulates regional cerebral glucose transporter expression in an age-specific and sexually-dimorphic manner

(2014) Sean D. Kelly et al.   PHYSIOLOGY & BEHAVIOR

Overactivation of corticotropin-releasing factor receptor type 1 and aquaporin-4 by hypoxia induces cerebral edema

(2014) S.-J. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The global burden of anxiety disorders in 2010

(2014) A. J. Baxter et al.   PSYCHOLOGICAL MEDICINE

Inflammatory activation is associated with a reduced glucocorticoid receptor alpha/beta expression ratio in monocytes of inpatients with melancholic major depressive disorder

(2014) L A Carvalho et al.   Translational Psychiatry

Paradoxical enhancement of fear expression and extinction deficits in mice resilient to social defeat

(2013) Jeremy D. Meduri et al.   BEHAVIOURAL BRAIN RESEARCH

Posttraumatic stress disorder is associated with an enhanced spontaneous production of pro-inflammatory cytokines by peripheral blood mononuclear cells

(2013) Hannah Gola et al.   BMC Psychiatry

Physiological Roles of Aquaporin-4 in Brain

(2013) Erlend A. Nagelhus et al.   PHYSIOLOGICAL REVIEWS

Coverage of Blood Vessels by Astrocytic Endfeet Is Reduced in Major Depressive Disorder

(2012) Grazyna Rajkowska et al.   BIOLOGICAL PSYCHIATRY

Stress-Induced Neuroinflammation: Role of the Toll-Like Receptor-4 Pathway

(2012) Iciar Gárate et al.   BIOLOGICAL PSYCHIATRY

Decreased expression of extracellular matrix proteins and trophic factors in the amygdala complex of depressed mice after chronic immobilization stress

(2012) Soonwoong Jung et al.   BMC NEUROSCIENCE

The inflammasome and danger associated molecular patterns (DAMPs) are implicated in cytokine and chemokine responses following stressor exposure

(2012) Thomas Maslanik et al.   BRAIN BEHAVIOR AND IMMUNITY

Deletion of Astroglial Connexins Weakens the Blood–Brain Barrier

(2012) Pascal Ezan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Persistent Neuroinflammatory Effects of Serial Exposure to Stress and Methamphetamine on the Blood-Brain Barrier

(2012) Nicole A. Northrop et al.   Journal of Neuroimmune Pharmacology

Aquaporin 4: a player in cerebral edema and neuroinflammation

(2012) Andrew M Fukuda et al.   Journal of Neuroinflammation

Prenatal stress causes alterations in the morphology of microglia and the inflammatory response of the hippocampus of adult female mice

(2012) Yolanda Diz-Chaves et al.   Journal of Neuroinflammation

Neurovascular Unit: a Focus on Pericytes

(2012) Inês Sá-Pereira et al.   MOLECULAR NEUROBIOLOGY

Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis

(2012) Ralf Gold et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mast cell-glia axis in neuroinflammation and therapeutic potential of the anandamide congener palmitoylethanolamide

(2012) S. D. Skaper et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

Update in the methodology of the chronic stress paradigm: internal control matters

(2011) Tatyana Strekalova et al.   Behavioral and Brain Functions

Central activation of the cholinergic anti-inflammatory pathway reduces surgical inflammation in experimental post-operative ileus

(2011) FO The et al.   BRITISH JOURNAL OF PHARMACOLOGY

NF-κB, Inflammation, and Metabolic Disease

(2011) Rebecca G. Baker et al.   Cell Metabolism

Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke

(2011) Kim M. Baeten et al.   Developmental Neurobiology

Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation

(2011) Lihua Li et al.   FASEB JOURNAL

Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*

(2011) Leonid Tarassishin et al.   GLIA

Role of endothelial nitric oxide synthase (eNOS) in chronic stress-promoted tumour growth

(2011) Antonio Barbieri et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Connexin Channels Provide a Target to Manipulate Brain Endothelial Calcium Dynamics and Blood—Brain Barrier Permeability

(2011) Marijke De Bock et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression

(2011) Iciar Gárate et al.   Journal of Neuroinflammation

Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation

(2011) Pratibha V Nerurkar et al.   Journal of Neuroinflammation

Differential aquaporin 4 expression during edema build-up and resolution phases of brain inflammation

(2011) Thomas Tourdias et al.   Journal of Neuroinflammation

Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?

(2011) Johann Steiner et al.   Journal of Neuroinflammation

A standardized protocol for repeated social defeat stress in mice

(2011) Sam A Golden et al.   Nature Protocols

Gap Junction Dysfunction in the Prefrontal Cortex Induces Depressive-Like Behaviors in Rats

(2011) Jian-Dong Sun et al.   NEUROPSYCHOPHARMACOLOGY

The Roles of BDNF in the Pathophysiology of Major Depression and in Antidepressant Treatment

(2011) Bun-Hee Lee et al.   Psychiatry Investigation

Stress Worsens Endothelial Function and Ischemic Stroke via Glucocorticoids

(2011) Mustafa Balkaya et al.   STROKE

Variant brain-derived neurotrophic factor Val66Met endophenotypes: implications for posttraumatic stress disorder

(2010) Helena Frielingsdorf et al.   Annals of the New York Academy of Sciences

Position Statement: Definition of Traumatic Brain Injury

(2010) David K. Menon et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions

(2010) Ross J. Tynan et al.   BRAIN BEHAVIOR AND IMMUNITY

Oxidative Stress Increases Blood–Brain Barrier Permeability and Induces Alterations in Occludin during Hypoxia–Reoxygenation

(2010) Jeffrey J Lochhead et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Extracellular Signal-Regulated Kinase-2 within the Ventral Tegmental Area Regulates Responses to Stress

(2010) S. D. Iniguez et al.   JOURNAL OF NEUROSCIENCE

Nuclear factor- B is a critical mediator of stress-impaired neurogenesis and depressive behavior

(2010) J. W. Koo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress-induced neuroinflammation: mechanisms and new pharmacological targets

(2009) C.D. Munhoz et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Permeability of the blood–brain barrier depends on brain temperature

(2009) E.A. Kiyatkin et al.   NEUROSCIENCE

Prevalence of stress, anxiety and depression in with Alzheimer caregivers

(2008) Maria Ferrara et al.   Health and Quality of Life Outcomes

Kynurenine pathway metabolism in human blood–brain–barrier cells: implications for immune tolerance & neurotoxicity

(2008) Robert Owe-Young et al.   JOURNAL OF NEUROCHEMISTRY

BDNF Modulation of NMDA Receptors Is Activity Dependent

(2008) Robert A. Crozier et al.   JOURNAL OF NEUROPHYSIOLOGY

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

(2008) T. Shibata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1–Cul3 interaction

(2008) Xiao-Jun Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY