Connexin Channels Provide a Target to Manipulate Brain Endothelial Calcium Dynamics and Blood—Brain Barrier Permeability

Engaging neuroscience to advance translational research in brain barrier biology

(2011) Edward A. Neuwelt et al.   NATURE REVIEWS NEUROSCIENCE

Connexin 43 hemichannels mediate the Ca2+ influx induced by extracellular alkalinization

(2010) Kurt A. Schalper et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Vimentin-mediated signalling is required for IbeA+E. coliK1 invasion of human brain microvascular endothelial cells

(2010) Feng Chi et al.   BIOCHEMICAL JOURNAL

Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity

(2010) Raf Ponsaerts et al.   FASEB JOURNAL

Inhibition of Bradykinin Receptor B1 Protects Mice from Focal Brain Injury by Reducing Blood–Brain Barrier Leakage and Inflammation

(2010) Furat Raslan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Pharmacological and genetic approaches to study connexin-mediated channels in glial cells of the central nervous system

(2009) Christian Giaume et al.   BRAIN RESEARCH REVIEWS

Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model

(2008) E Decrock et al.   CELL DEATH AND DIFFERENTIATION

Perturbing plasma membrane hemichannels attenuates calcium signalling in cardiac cells and HeLa cells expressing connexins

(2008) Vandana Verma et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Cytosolic Ca2+ Oscillations in Human Cerebrovascular Endothelial Cells after Subarachnoid Hemorrhage

(2008) Wolfram Scharbrodt et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Connexin 43 Hemichannels Are Permeable to ATP

(2008) J. Kang et al.   JOURNAL OF NEUROSCIENCE

Bradykinin increases blood–tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin cytoskeleton

(2008) Li-bo Liu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Blockade of Bradykinin Receptor B1 but Not Bradykinin Receptor B2 Provides Protection From Cerebral Infarction and Brain Edema

(2008) Madeleine Austinat et al.   STROKE