Hyperoside Protects Human Umbilical Vein Endothelial Cells Against Anticardiolipin Antibody-Induced Injury by Activating Autophagy

Inactivation of MTOR promotes autophagy-mediated epithelial injury in particulate matter-induced airway inflammation

(2019) Yin-Fang Wu et al.   Autophagy

MicroRNA-9-5p promotes angiogenesis but inhibits apoptosis and inflammation of high glucose-induced injury in human umbilical vascular endothelial cells by targeting CXCR4

(2019) Jun Yi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Cardiac Manifestations of Antiphospholipid Syndrome With Focus on Its Primary Form

(2019) Tamara Kolitz et al.   Frontiers in Immunology

Lipoxin A4 restores oxidative stress-induced vascular endothelial cell injury and thrombosis-related factor expression by its receptor-mediated activation of Nrf2-HO-1 axis

(2019) Songbai Yang et al.   CELLULAR SIGNALLING

Autophagy balances inflammation in innate immunity

(2018) Vojo Deretic et al.   Autophagy

Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium

(2018) Anastasia Sacharidou et al.   BLOOD

Survivin regulated by autophagy mediates hyperglycemia-induced vascular endothelial cell dysfunction

(2018) Yu-Xue Xu et al.   EXPERIMENTAL CELL RESEARCH

Inhibition of miR-135b by SP-1 promotes hypoxia-induced vascular endothelial cell injury via HIF-1α

(2018) Songbai Yang et al.   EXPERIMENTAL CELL RESEARCH

Alterations of apoptosis and autophagy in developing brain of rats with epilepsy: Changes in LC3, P62, Beclin-1 and Bcl-2 levels

(2018) Qinrui Li et al.   NEUROSCIENCE RESEARCH

Beneficial effects of hyperoside on bone metabolism in ovariectomized mice

(2018) Yiqing Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Antiphospholipid syndrome – an update

(2018) Birgit Linnemann   Vasa-European Journal of Vascular Medicine

Loss of VAPB Regulates Autophagy in a Beclin 1-Dependent Manner

(2018) Dan Wu et al.   Neuroscience Bulletin

Boosting mTOR-dependent autophagy via upstream TLR4-MyD88-MAPK signalling and downstream NF-κB pathway quenches intestinal inflammation and oxidative stress injury

(2018) Mingxia Zhou et al.   EBioMedicine

Endothelial cell injury is involved in atherosclerosis and lupus symptoms in gld.apoE − / − mice

(2018) Genhong Yao et al.   International Journal of Rheumatic Diseases

Autophagic dysfunction in Alzheimer’s disease: Cellular and molecular mechanistic approaches to halt Alzheimer’s pathogenesis

(2018) Md. Sahab Uddin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

PGRMC1-dependent autophagy by hyperoside induces apoptosis and sensitizes ovarian cancer cells to cisplatin treatment

(2017) Xiaofei Zhu et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Antiphospholipid Syndrome

(2017) Michel T. Corban et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cytokines in Endocrine Dysfunction of Plasma Cell Disorders

(2017) Eva Feigerlová et al.   MEDIATORS OF INFLAMMATION

Mecanismos de aterosclerosis y enfermedad cardiovascular en el síndrome antifosfolípido y el lupus eritematoso sistémico. Alternativas terapéuticas

(2017) Chary Lopez-Pedrera et al.   MEDICINA CLINICA

The IL-1β signalling pathway and its role in regulating pro-inflammatory and pro-labour mediators in human primary myometrial cells

(2017) Martha Lappas   Reproductive Biology

Activation of mTOR is involved in anti-β 2 GPI/β 2 GPI-induced expression of tissue factor and IL-8 in monocytes

(2017) Longfei Xia et al.   THROMBOSIS RESEARCH

Major Histocompatibility Complex Class II Alleles Influence Induction of Pathogenic Antiphospholipid Antibodies in a Mouse Model of Thrombosis

(2017) Elizabeth Papalardo et al.   Arthritis & Rheumatology

In Vivo Role of Neutrophil Extracellular Traps in Antiphospholipid Antibody-Mediated Venous Thrombosis

(2017) He Meng et al.   Arthritis & Rheumatology

Hyperoside induces both autophagy and apoptosis in non-small cell lung cancer cells in vitro

(2016) Ting Fu et al.   ACTA PHARMACOLOGICA SINICA

The preventive effects of hyperoside on lung cancer in vitro by inducing apoptosis and inhibiting proliferation through Caspase-3 and P53 signaling pathway

(2016) Yuan-hua Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Folic Acid Attenuates Vascular Endothelial Cell Injury Caused by Hypoxia via the Inhibition of ERK1/2/NOX4/ROS Pathway

(2016) Fei Cheng et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

p62 links the autophagy pathway and the ubiqutin–proteasome system upon ubiquitinated protein degradation

(2016) Wei Jing Liu et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Protective effect of hyperoside against acetaminophen (APAP) induced liver injury through enhancement of APAP clearance

(2016) Wenyan Xie et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling

(2016) Caixia Guo et al.   International Journal of Nanomedicine

Cofactor-independent human antiphospholipid antibodies induce venous thrombosis in mice

(2016) D. Manukyan et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Protective effects of hyperoside against H2O2-induced apoptosis in human umbilical vein endothelial cells

(2016) XU-LIANG HAO et al.   Molecular Medicine Reports

Hyperoside protects human primary melanocytes against H2O2-induced oxidative damage

(2016) BIN YANG et al.   Molecular Medicine Reports

TNF-alpha and annexin A2: inflammation in thrombotic primary antiphospholipid syndrome

(2016) Mirjana Bećarević   RHEUMATOLOGY INTERNATIONAL

Heat shock response and autophagy—cooperation and control

(2015) Karol Dokladny et al.   Autophagy

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Infliximab improves endothelial dysfunction in a mouse model of antiphospholipid syndrome: Role of reduced oxidative stress

(2015) Ygal Benhamou et al.   VASCULAR PHARMACOLOGY

Rapamycin: One Drug, Many Effects

(2014) Jing Li et al.   Cell Metabolism

Autophagy in aging and in neurodegenerative disorders

(2014) Yogendra Rajawat et al.   Hormones-International Journal of Endocrinology and Metabolism

Diagnosis and classification of the antiphospholipid syndrome

(2014) Jose A. Gómez-Puerta et al.   JOURNAL OF AUTOIMMUNITY

Synthesis and screening of 3-MA derivatives for autophagy inhibitors

(2013) Yanyang Wu et al.   Autophagy

Cold induces reactive oxygen species production and activation of the NF-kappa B response in endothelial cells and inflammationin vivo

(2013) E. M. Awad et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Protective effects of hyperoside against human umbilical vein endothelial cell damage induced by hydrogen peroxide

(2011) Zi-lin Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Prevalence and Clinical Associations of Lupus Anticoagulant, Anticardiolipin Antibodies, and Anti-beta2-glycoprotein I Antibodies in Patients with Systemic Lupus Erythematosus

(2010) Kwang-Sook Woo et al.   Korean Journal of Laboratory Medicine