The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection
Authors
Keywords
-
Journal
eLife
Volume 9, Issue -, Pages -
Publisher
eLife Sciences Publications, Ltd
Online
2020-05-04
DOI
10.7554/elife.55692
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- An evolutionary perspective on immunometabolism
- (2019) Andrew Wang et al. SCIENCE
- Metformin as a host-directed therapeutic in tuberculosis: Is there a promise?
- (2019) Wing Wai Yew et al. TUBERCULOSIS
- Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation
- (2019) Nina Germic et al. CELL DEATH AND DIFFERENTIATION
- Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages
- (2019) Daniel J. Greenwood et al. SCIENCE
- Aryl Hydrocarbon Receptor Modulation by Tuberculosis Drugs Impairs Host Defense and Treatment Outcomes
- (2019) Andreas Puyskens et al. Cell Host & Microbe
- Macrophages and lipid metabolism
- (2018) Anneleen Remmerie et al. CELLULAR IMMUNOLOGY
- Ionophoric effects of the antitubercular drug bedaquiline
- (2018) Kiel Hards et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The lysosome as a cellular centre for signalling, metabolism and quality control
- (2018) Rosalie E. Lawrence et al. NATURE CELL BIOLOGY
- Lysosome: The metabolic signaling hub
- (2018) Dudley W. Lamming et al. TRAFFIC
- Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis
- (2017) Roni Levin et al. MOLECULAR BIOLOGY OF THE CELL
- Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)
- (2016) Marco Fiorillo et al. Aging-US
- p62 links the autophagy pathway and the ubiqutin–proteasome system upon ubiquitinated protein degradation
- (2016) Wei Jing Liu et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Effect of isoniazid preventive therapy on immune responses to mycobacterium tuberculosis: an open label randomised, controlled, exploratory study
- (2015) Irene Andia Biraro et al. BMC INFECTIOUS DISEASES
- Macrophage defense mechanisms against intracellular bacteria
- (2015) Günter Weiss et al. IMMUNOLOGICAL REVIEWS
- Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
- (2015) Diego L. Medina et al. NATURE CELL BIOLOGY
- TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1
- (2015) Monika Plescher et al. Scientific Reports
- Host Evasion and Exploitation Schemes of Mycobacterium tuberculosis
- (2014) C.J. Cambier et al. CELL
- An efficient siRNA-mediated gene silencing in primary human monocytes, dendritic cells and macrophages
- (2014) Anthony Troegeler et al. IMMUNOLOGY AND CELL BIOLOGY
- Isoniazid Induces Apoptosis Of Activated CD4+T Cells
- (2014) Sultan Tousif et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multidrug-Resistant Tuberculosis and Culture Conversion with Bedaquiline
- (2014) Andreas H. Diacon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Metformin as adjunct antituberculosis therapy
- (2014) A. Singhal et al. Science Translational Medicine
- Phosphatidylinositol-4-phosphate: The Golgi and beyond
- (2013) Maria A. De Matteis et al. BIOESSAYS
- Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain
- (2013) Xiaohui Wang et al. FASEB JOURNAL
- Macrophage biology in development, homeostasis and disease
- (2013) Thomas A. Wynn et al. NATURE
- High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states
- (2013) Ronnie Blecher-Gonen et al. Nature Protocols
- Host Targeted Activity of Pyrazinamide in Mycobacterium tuberculosis Infection
- (2013) Claudia Manca et al. PLoS One
- Randomized Pilot Trial of Eight Weeks of Bedaquiline (TMC207) Treatment for Multidrug-Resistant Tuberculosis: Long-Term Outcome, Tolerability, and Effect on Emergence of Drug Resistance
- (2012) A. H. Diacon et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Drug induced phospholipidosis: An acquired lysosomal storage disorder
- (2012) James A. Shayman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Host Cell Autophagy Activated by Antibiotics Is Required for Their Effective Antimycobacterial Drug Action
- (2012) Jwa-Jin Kim et al. Cell Host & Microbe
- A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
- (2012) Carmine Settembre et al. EMBO JOURNAL
- Polymorphisms in the SLC11A1 gene and tuberculosis risk: a meta-analysis update [Review article]
- (2012) Q. Meilang et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Physiological Roles of Mitochondrial Reactive Oxygen Species
- (2012) Laura A. Sena et al. MOLECULAR CELL
- Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection
- (2012) L. B. Barreiro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
- (2012) A. Roczniak-Ferguson et al. Science Signaling
- Antibiotics, microbiota, and immune defense
- (2012) Carles Ubeda et al. TRENDS IN IMMUNOLOGY
- Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death
- (2012) Roxane Simeone et al. PLoS Pathogens
- Rifampicin inhibits microglial inflammation and improves neuron survival against inflammation
- (2011) Wei Bi et al. BRAIN RESEARCH
- Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
- (2011) Michela Palmieri et al. HUMAN MOLECULAR GENETICS
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- Rifampicin – A mild immunosuppressive agent for psoriasis
- (2010) Nikolai Tsankov et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Mycobacterium tuberculosis Eis Regulates Autophagy, Inflammation, and Cell Death through Redox-dependent Signaling
- (2010) Dong-Min Shin et al. PLoS Pathogens
- ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
- (2009) Gabriela Bindea et al. BIOINFORMATICS
- Selectivity of TMC207 towards Mycobacterial ATP Synthase Compared with That towards the Eukaryotic Homologue
- (2008) A. C. Haagsma et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and Macrophages
- (2008) Ludovic Tailleux et al. PLoS One
- Long term efficacy of DOTS regimens for tuberculosis: systematic review
- (2008) Helen S Cox et al. BMJ-British Medical Journal
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search