Phosphatidylinositol-4-phosphate: The Golgi and beyond

Growth and metabolic control of lipid signalling at the Golgi

(2012) Hailan Piao et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Connecting vesicular transport with lipid synthesis: FAPP2

(2012) Giovanni D'Angelo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Sterol-Binding Protein Integrates Endosomal Lipid Metabolism with TOR Signaling and Nitrogen Sensing

(2012) Carl J. Mousley et al.   CELL

Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila

(2012) J. Burgess et al.   DEVELOPMENT

Myosin-V Is Activated by Binding Secretory Cargo and Released in Coordination with Rab/Exocyst Function

(2012) Kirk W. Donovan et al.   DEVELOPMENTAL CELL

The lipid kinase PI4KIIIβ preserves lysosomal identity

(2012) Sunandini Sridhar et al.   EMBO JOURNAL

Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch

(2012) Julia Mössinger et al.   EMBO REPORTS

Phosphatidylinositol 4-Kinases Are Required for Autophagic Membrane Trafficking

(2012) Ke Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Phosphatidylinositol 4-Phosphate (PI4P) and Its Binding Protein GOLPH3 in Hepatitis C Virus Secretion

(2012) Bryan Bishé et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Golgi Phosphoprotein 3 Determines Cell Binding Properties under Dynamic Flow by Controlling Golgi Localization of Core 2N-Acetylglucosaminyltransferase 1

(2012) Mohamed F. Ali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylinositol 4-Kinase IIα Is Palmitoylated by Golgi-localized Palmitoyltransferases in Cholesterol-dependent Manner

(2012) Dongmei Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity

(2012) Fubito Nakatsu et al.   JOURNAL OF CELL BIOLOGY

The 3A Protein from Multiple Picornaviruses Utilizes the Golgi Adaptor Protein ACBD3 To Recruit PI4KIII 

(2012) A. L. Greninger et al.   JOURNAL OF VIROLOGY

Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase

(2012) Christopher S. Wood et al.   MOLECULAR BIOLOGY OF THE CELL

Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase

(2012) Marko Jović et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphoinositide-mediated clathrin adaptor progression at the trans-Golgi network

(2012) Lydia Daboussi et al.   NATURE CELL BIOLOGY

A 14-3-3γ dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIIIβ to regulate post-Golgi carrier formation

(2012) Carmen Valente et al.   NATURE CELL BIOLOGY

PI4P and PI(4,5)P2 Are Essential But Independent Lipid Determinants of Membrane Identity

(2012) G. R. V. Hammond et al.   SCIENCE

A Conserved N-terminal Arginine-Motif in GOLPH3-Family Proteins Mediates Binding to Coatomer

(2012) Linna Tu et al.   TRAFFIC

Metabolic Activation of the HOG MAP Kinase Pathway by Snf1/AMPK Regulates Lipid Signaling at the Golgi

(2012) Hailan Piao et al.   TRAFFIC

Phosphoinositides in the Hepatitis C Virus Life Cycle

(2012) Bryan Bishé et al.   Viruses-Basel

Genetic and functional studies of phosphatidyl-inositol 4-kinase type IIIα

(2011) Zsofia Szentpetery et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites

(2011) Christopher J. Stefan et al.   CELL

Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment

(2011) Simon Reiss et al.   Cell Host & Microbe

WNK1 Promotes PIP2 Synthesis to Coordinate Growth Factor and GPCR-Gq Signaling

(2011) Sung-Wan An et al.   CURRENT BIOLOGY

Lipid transfer and signaling at organelle contact sites: the tip of the iceberg

(2011) Alexandre Toulmay et al.   CURRENT OPINION IN CELL BIOLOGY

Myosin V Transports Secretory Vesicles via a Rab GTPase Cascade and Interaction with the Exocyst Complex

(2011) Yui Jin et al.   DEVELOPMENTAL CELL

PI4P and Rab Inputs Collaborate in Myosin-V-Dependent Transport of Secretory Compartments in Yeast

(2011) Felipe H. Santiago-Tirado et al.   DEVELOPMENTAL CELL

ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites

(2011) Jun Sasaki et al.   EMBO JOURNAL

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

(2011) Maud de Saint-Jean et al.   JOURNAL OF CELL BIOLOGY

c-Fos activates and physically interacts with specific enzymes of the pathway of synthesis of polyphosphoinositides

(2011) Adolfo R. Alfonso Pecchio et al.   MOLECULAR BIOLOGY OF THE CELL

Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae

(2011) F. M. Roelants et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Sterol-Binding Protein Kes1/Osh4p Is a Regulator of Polarized Exocytosis

(2011) Gabriel Alfaro et al.   TRAFFIC

Chlamydia trachomatis Co-opts GBF1 and CERT to Acquire Host Sphingomyelin for Distinct Roles during Intracellular Development

(2011) Cherilyn A. Elwell et al.   PLoS Pathogens

Anchors for Effectors: Subversion of Phosphoinositide Lipids by Legionella

(2011) Hubert Hilbi et al.   Frontiers in Microbiology

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

Phosphatidylinositol 4-Phosphate Controls Both Membrane Recruitment and a Regulatory Switch of the Rab GEF Sec2p

(2010) Emi Mizuno-Yamasaki et al.   DEVELOPMENTAL CELL

Multiple Host Proteins That Function in Phosphatidylinositol-4-Phosphate Metabolism Are Recruited to the Chlamydial Inclusion

(2010) A. M. Moorhead et al.   INFECTION AND IMMUNITY

Gene expression profiling reveals novel biomarkers in nonsmall cell lung cancer

(2010) Abel Sanchez-Palencia et al.   INTERNATIONAL JOURNAL OF CANCER

Lipid Binding Requirements for Oxysterol-binding Protein Kes1 Inhibition of Autophagy and Endosome-trans-Golgi Trafficking Pathways

(2010) Marissa A. LeBlanc et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interruption of Inositol Sphingolipid Synthesis Triggers Stt4p-dependent Protein Kinase C Signaling

(2010) Stephen A. Jesch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylinositol 4-Kinase III Beta Is a Target of Enviroxime-Like Compounds for Antipoliovirus Activity

(2010) M. Arita et al.   JOURNAL OF VIROLOGY

Orm family proteins mediate sphingolipid homeostasis

(2010) David K. Breslow et al.   NATURE

PI4KIIα is a novel regulator of tumor growth by its action on angiogenesis and HIF-1α regulation

(2010) J Li et al.   ONCOGENE

Differential effects of the phosphatidylinositol 4-kinases, PI4KIIα and PI4KIIIβ, on Akt activation and apoptosis

(2010) K M E Chu et al.   Cell Death & Disease

Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue

(2009) Dung-Tsa Chen et al.   BREAST CANCER RESEARCH AND TREATMENT

GOLPH3 Bridges Phosphatidylinositol-4- Phosphate and Actomyosin to Stretch and Shape the Golgi to Promote Budding

(2009) Holly C. Dippold et al.   CELL

A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication

(2009) Andrew W. Tai et al.   Cell Host & Microbe

Palmitoylation Controls the Catalytic Activity and Subcellular Distribution of Phosphatidylinositol 4-Kinase IIα

(2009) Barbara Barylko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of Sphingolipid Metabolism by the Phosphatidylinositol-4-phosphate Phosphatase Sac1p through Regulation of Phosphatidylinositol inSaccharomyces cerevisiae

(2009) Sarah E. Brice et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PtdIns4Precognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking

(2009) Christopher S. Wood et al.   JOURNAL OF CELL BIOLOGY

Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network

(2009) Robin W. Klemm et al.   JOURNAL OF CELL BIOLOGY

Role of Oxysterol Binding Protein in Hepatitis C Virus infection

(2009) Y. Amako et al.   JOURNAL OF VIROLOGY

Oxysterol Binding Protein–related Protein 9 (ORP9) Is a Cholesterol Transfer Protein That Regulates Golgi Structure and Function

(2009) Mike Ngo et al.   MOLECULAR BIOLOGY OF THE CELL

GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer

(2009) Kenneth L. Scott et al.   NATURE

Regulation of a Golgi flippase by phosphoinositides and an ArfGEF

(2009) Paramasivam Natarajan et al.   NATURE CELL BIOLOGY

Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication

(2009) K. L. Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular determinants of activation and membrane targeting of phosphoinositol 4-kinase IIβ

(2008) Gwanghyun Jung et al.   BIOCHEMICAL JOURNAL

Epithelial Progeny of Estrogen-Exposed Breast Progenitor Cells Display a Cancer-like Methylome

(2008) A. S.L. Cheng et al.   CANCER RESEARCH

TheLegionella pneumophilaphosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole

(2008) Curdin Ragaz et al.   CELLULAR MICROBIOLOGY

Lipid-transfer proteins in biosynthetic pathways

(2008) Giovanni D’Angelo et al.   CURRENT OPINION IN CELL BIOLOGY

Golgi Localization of Glycosyltransferases Requires a Vps74p Oligomer

(2008) Karl R. Schmitz et al.   DEVELOPMENTAL CELL

Two sphingolipid transfer proteins, CERT and FAPP2: Their roles in sphingolipid metabolism

(2008) Toshiyuki Yamaji et al.   IUBMB LIFE

Rab1 Guanine Nucleotide Exchange Factor SidM Is a Major Phosphatidylinositol 4-Phosphate-binding Effector Protein ofLegionella pneumophila

(2008) Eva Brombacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3

(2008) Dan Baird et al.   JOURNAL OF CELL BIOLOGY

Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1

(2008) Anastasia Blagoveshchenskaya et al.   JOURNAL OF CELL BIOLOGY

The multiple roles of PtdIns(4)P - not just the precursor of PtdIns(4,5)P2

(2008) G. D'Angelo et al.   JOURNAL OF CELL SCIENCE

The Clathrin Adaptor Gga2p Is a Phosphatidylinositol 4-phosphate Effector at the Golgi Exit

(2008) Lars Demmel et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphatidylinositol-4-Kinase Type II Alpha Contains an AP-3–sorting Motif and a Kinase Domain That Are Both Required for Endosome Traffic

(2008) Branch Craige et al.   MOLECULAR BIOLOGY OF THE CELL

Nucleocytoplasmic Shuttling of the Golgi Phosphatidylinositol 4-Kinase Pik1 Is Regulated by 14-3-3 Proteins and Coordinates Golgi Function with Cell Growth

(2008) Lars Demmel et al.   MOLECULAR BIOLOGY OF THE CELL

SAC1 lipid phosphatase and growth control of the secretory pathway

(2008) Anastasia Blagoveshchenskaya et al.   Molecular BioSystems

Ypt32p and Mlc1p bind within the vesicle binding region of the class V myosin Myo2p globular tail domain

(2008) Elena Caroli Casavola et al.   MOLECULAR MICROBIOLOGY

Signal-Mediated Dynamic Retention of Glycosyltransferases in the Golgi

(2008) L. Tu et al.   SCIENCE

Maintenance of Hormone-sensitive Phosphoinositide Pools in the Plasma Membrane Requires Phosphatidylinositol 4-Kinase IIIα

(2007) Andras Balla et al.   MOLECULAR BIOLOGY OF THE CELL