Satellite cells in ageing: use it or lose it

YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow

(2020) Vanessa Lundin et al.   DEVELOPMENTAL CELL

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

(2020) Jessica Segalés et al.   Nature Communications

Role of Metabolic Stress and Exercise in Regulating Fibro/Adipogenic Progenitors

(2020) Nicolas Collao et al.   Frontiers in Cell and Developmental Biology

Murine Tissue‐Resident PDGFRα+ Fibro‐Adipogenic Progenitors Spontaneously Acquire Osteogenic Phenotype in an Altered Inflammatory Environment

(2020) Christine Eisner et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity

(2019) Gabriel M. Pagnotti et al.   Nature Reviews Endocrinology

Stem Cell Quiescence: Dynamism, Restraint, and Cellular Idling

(2019) Cindy T.J. van Velthoven et al.   Cell Stem Cell

Lateral Inhibition in Cell Specification Mediated by Mechanical Signals Modulating TAZ Activity

(2019) Peng Xia et al.   CELL

mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism

(2019) Huibin Tang et al.   AGING CELL

The role of SIRT1 in skeletal muscle function and repair of older mice

(2019) Matthew J. Myers et al.   Journal of Cachexia Sarcopenia and Muscle

Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells

(2019) Susan Eliazer et al.   Cell Stem Cell

Fibro–Adipogenic Progenitors Cross-Talk in Skeletal Muscle: The Social Network

(2019) Beatrice Biferali et al.   Frontiers in Physiology

The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells

(2019) Lidan Zhang et al.   Cell Reports

DNA damage responses in ageing

(2019) Paulo F. L. da Silva et al.   Open Biology

Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women

(2018) Antonio García-Hermoso et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a -Mediated Inhibition of the Dlk1-Dio3 Mega Gene Cluster

(2018) Stas Wüst et al.   Cell Metabolism

Muscle Stem Cells Exhibit Distinct Clonal Dynamics in Response to Tissue Repair and Homeostatic Aging

(2018) Matthew T. Tierney et al.   Cell Stem Cell

Waking up muscle stem cells: PI3K signalling is ringing

(2018) Frederic Relaix et al.   EMBO JOURNAL

Effects of exercise improves muscle strength and fat mass in patients with high fracture risk: A randomized control trial

(2018) Ding-Cheng Chan et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

The Contributions of Fiber Atrophy, Fiber Loss, In Situ Specific Force, and Voluntary Activation to Weakness in Sarcopenia

(2018) Jamie S McPhee et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M

(2018) Srinath C. Sampath et al.   Nature Communications

Maintenance of Skeletal Muscle Mitochondria in Health, Exercise, and Aging

(2018) David A. Hood et al.   Annual Review of Physiology

Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells

(2018) Ling Liu et al.   Cell Stem Cell

Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis

(2018) Francesca Pala et al.   JOURNAL OF CELL SCIENCE

Reciprocal signalling by Notch–Collagen V–CALCR retains muscle stem cells in their niche

(2018) Meryem B. Baghdadi et al.   NATURE

Notch-Induced miR-708 Antagonizes Satellite Cell Migration and Maintains Quiescence

(2018) Meryem B. Baghdadi et al.   Cell Stem Cell

Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling

(2018) Mayank Verma et al.   Cell Stem Cell

Orienting Muscle Stem Cells for Regeneration in Homeostasis, Aging, and Disease

(2018) Peter Feige et al.   Cell Stem Cell

The Ubiquitin-Proteasome System Is Indispensable for the Maintenance of Muscle Stem Cells

(2018) Yasuo Kitajima et al.   Stem Cell Reports

Effects of Acute and Chronic Exercise on Immunological Parameters in the Elderly Aged: Can Physical Activity Counteract the Effects of Aging?

(2018) Maha Sellami et al.   Frontiers in Immunology

Changes in health-related quality of life in elderly men after 12 weeks of strength training

(2017) Kristin Haraldstad et al.   European Review of Aging and Physical Activity

DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation

(2017) Lucia Latella et al.   GENES & DEVELOPMENT

The metabolic programming of stem cells

(2017) Ng Shyh-Chang et al.   GENES & DEVELOPMENT

Satellite cell activation induced by aerobic muscle adaptation in response to endurance exercise in humans and rodents

(2017) Phablo Abreu et al.   LIFE SCIENCES

Physical function and exercise training in older patients with heart failure

(2017) Andrew J. Stewart Coats et al.   Nature Reviews Cardiology

Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence

(2017) Antoine de Morrée et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Situ Fixation Redefines Quiescence and Early Activation of Skeletal Muscle Stem Cells

(2017) Léo Machado et al.   Cell Reports

HGFA Is an Injury-Regulated Systemic Factor that Induces the Transition of Stem Cells into G Alert

(2017) Joseph T. Rodgers et al.   Cell Reports

Transcriptional Profiling of Quiescent Muscle Stem Cells In Vivo

(2017) Cindy T.J. van Velthoven et al.   Cell Reports

Niche Cadherins Control the Quiescence-to-Activation Transition in Muscle Stem Cells

(2017) Aviva J. Goel et al.   Cell Reports

Molecular Regulation of Exercise-Induced Muscle Fiber Hypertrophy

(2017) Marcas M. Bamman et al.   Cold Spring Harbor Perspectives in Medicine

Autophagy is a key factor in maintaining the regenerative capacity of muscle stem cells by promoting quiescence and preventing senescence

(2016) Xin Wen et al.   Autophagy

Dysfunctional autophagy is a driver of muscle stem cell functional decline with aging

(2016) Laura García-Prat et al.   Autophagy

Autophagy regulates satellite cell ability to regenerate normal and dystrophic muscles

(2016) E Fiacco et al.   CELL DEATH AND DIFFERENTIATION

Exercise Promotes Healthy Aging of Skeletal Muscle

(2016) Gregory D. Cartee et al.   Cell Metabolism

Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal

(2016) Victoria Zismanov et al.   Cell Stem Cell

Lost in Translation: Preserving Satellite Cell Function with Global Translational Control

(2016) Susan Eliazer et al.   Cell Stem Cell

Redox Regulation by Pitx2 and Pitx3 Is Critical for Fetal Myogenesis

(2016) Aurore L'honoré et al.   DEVELOPMENTAL CELL

Effect of Exercise Training on Skeletal Muscle SIRT1 and PGC-1α Expression Levels in Rats of Different Age

(2016) Chi-Chang Huang et al.   International Journal of Medical Sciences

Sex hormones establish a reserve pool of adult muscle stem cells

(2016) Ji-Hoon Kim et al.   NATURE CELL BIOLOGY

Targeting β1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice

(2016) Michelle Rozo et al.   NATURE MEDICINE

Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis

(2016) Matthew T. Tierney et al.   TRENDS IN CELL BIOLOGY

A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood

(2016) Justin Rebo et al.   Nature Communications

Comparative Study of Injury Models for Studying Muscle Regeneration in Mice

(2016) David Hardy et al.   PLoS One

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

(2015) James G. Ryall et al.   Cell Stem Cell

NEDD4 Regulates PAX7 Levels Promoting Activation of the Differentiation Program in Skeletal Muscle Precursors

(2015) Francisco Bustos et al.   STEM CELLS

Age-Associated Methylation Suppresses SPRY1 , Leading to a Failure of Re-quiescence and Loss of the Reserve Stem Cell Pool in Elderly Muscle

(2015) Anne Bigot et al.   Cell Reports

Satellite cells in human skeletal muscle plasticity

(2015) Tim Snijders et al.   Frontiers in Physiology

The skeletal muscle satellite cell response to a single bout of resistance-type exercise is delayed with aging in men

(2014) Tim Snijders et al.   AGE

Whey protein supplementation accelerates satellite cell proliferation during recovery from eccentric exercise

(2014) Jean Farup et al.   AMINO ACIDS

Novel TAZ modulators enhance myogenic differentiation and muscle regeneration

(2014) Gun Hwa Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Hippo Transducer YAP1 Transforms Activated Satellite Cells and Is a Potent Effector of Embryonal Rhabdomyosarcoma Formation

(2014) Annie M. Tremblay et al.   CANCER CELL

Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis

(2014) Rajesh R. Rao et al.   CELL

Quiescent Hematopoietic Stem Cells Accumulate DNA Damage during Aging that Is Repaired upon Entry into Cell Cycle

(2014) Isabel Beerman et al.   Cell Stem Cell

Early forming label-retaining muscle stem cells require p27kip1 for maintenance of the primitive state

(2014) J. V. Chakkalakal et al.   DEVELOPMENT

Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation

(2014) Ann H Tang et al.   EMBO JOURNAL

Glucocorticoids increase adipocytes in muscle by affecting IL-4 regulated FAP activity

(2014) Yanjun Dong et al.   FASEB JOURNAL

Influence of exercise contraction mode and protein supplementation on human skeletal muscle satellite cell content and muscle fiber growth

(2014) Jean Farup et al.   JOURNAL OF APPLIED PHYSIOLOGY

The role of satellite cells in muscle hypertrophy

(2014) Bert Blaauw et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert

(2014) Joseph T. Rodgers et al.   NATURE

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Inhibition of JAK-STAT signaling stimulates adult satellite cell function

(2014) Feodor D Price et al.   NATURE MEDICINE

STAT3 signaling controls satellite cell expansion and skeletal muscle repair

(2014) Matthew Timothy Tierney et al.   NATURE MEDICINE

Muscular strength and physical function in elderly adults 6–18 months after a 12-week resistance exercise program

(2014) Olof Gudny Geirsdottir et al.   SCANDINAVIAN JOURNAL OF PUBLIC HEALTH

Identification and characterization of PDGFRα+ mesenchymal progenitors in human skeletal muscle

(2014) A Uezumi et al.   Cell Death & Disease

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration

(2014) Christian Elabd et al.   Nature Communications

Differential satellite cell density of type I and II fibres with lifelong endurance running in old men

(2013) A. L. Mackey et al.   Acta Physiologica

Satellite cells in human skeletal muscle; from birth to old age

(2013) Lex B. Verdijk et al.   AGE

Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells

(2013) Mara Fornaro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

(2013) Jose E. Heredia et al.   CELL

DNA damage-activated ABL-MyoD signaling contributes to DNA repair in skeletal myoblasts

(2013) M Simonatto et al.   CELL DEATH AND DIFFERENTIATION

Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation

(2013) Brendan Egan et al.   Cell Metabolism

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

(2013) Chiara Mozzetta et al.   EMBO Molecular Medicine

Evidence for the contribution of muscle stem cells to nonhypertrophic skeletal muscle remodeling in humans

(2013) Sophie Joanisse et al.   FASEB JOURNAL

Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells

(2013) Laura García-Prat et al.   FEBS Journal

Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword?

(2013) Pura Muñoz-Cánoves et al.   FEBS Journal

Ageing is associated with diminished muscle re-growth and myogenic precursor cell expansion early after immobility-induced atrophy in human skeletal muscle

(2013) C. Suetta et al.   JOURNAL OF PHYSIOLOGY-LONDON

Satellite Cells and the Muscle Stem Cell Niche

(2013) Hang Yin et al.   PHYSIOLOGICAL REVIEWS

Early Activation of Rat Skeletal Muscle IL-6/STAT1/STAT3 Dependent Gene Expression in Resistance Exercise Linked to Hypertrophy

(2013) Gwénaëlle Begue et al.   PLoS One

Srf-Dependent Paracrine Signals Produced by Myofibers Control Satellite Cell-Mediated Skeletal Muscle Hypertrophy

(2012) Aline Guerci et al.   Cell Metabolism

Muscle Satellite Cells Are Primed for Myogenesis but Maintain Quiescence with Sequestration of Myf5 mRNA Targeted by microRNA-31 in mRNP Granules

(2012) Colin G. Crist et al.   Cell Stem Cell

Oxidative stress and disuse muscle atrophy

(2012) Scott K. Powers et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Myostatin is associated with age-related human muscle stem cell dysfunction

(2012) Bryon R. McKay et al.   FASEB JOURNAL

The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells

(2012) R. N. Judson et al.   JOURNAL OF CELL SCIENCE

Maintenance of muscle stem-cell quiescence by microRNA-489

(2012) Tom H. Cheung et al.   NATURE

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differentially Activated Macrophages Orchestrate Myogenic Precursor Cell Fate During Human Skeletal Muscle Regeneration

(2012) Marielle Saclier et al.   STEM CELLS

Building Muscle: Molecular Regulation of Myogenesis

(2012) C. F. Bentzinger et al.   Cold Spring Harbor Perspectives in Biology

Effects of Physical Activity and Inactivity on Muscle Fatigue

(2012) Gregory C. Bogdanis   Frontiers in Physiology

Mechano-Growth Factor: an important cog or a loose screw in the repair machinery?

(2012) Barbara Zabłocka et al.   Frontiers in Endocrinology

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Strength training increases the size of the satellite cell pool in type I and II fibres of chronically painful trapezius muscle in females

(2011) Abigail L. Mackey et al.   JOURNAL OF PHYSIOLOGY-LONDON

Satellite cells, the engines of muscle repair

(2011) Yu Xin Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Critical Requirement for Notch Signaling in Maintenance of the Quiescent Skeletal Muscle Stem Cell State

(2011) Philippos Mourikis et al.   STEM CELLS

Notch Signaling Is Necessary to Maintain Quiescence in Adult Muscle Stem Cells

(2011) Christopher R.R. Bjornson et al.   STEM CELLS

Resistance exercise for muscular strength in older adults: A meta-analysis

(2010) Mark D. Peterson et al.   AGEING RESEARCH REVIEWS

Sprouty1 Regulates Reversible Quiescence of a Self-Renewing Adult Muscle Stem Cell Pool during Regeneration

(2010) Kelly L. Shea et al.   Cell Stem Cell

Effects of Age and Sedentary Lifestyle on Skeletal Muscle NF- B Signaling in Men

(2010) T. W. Buford et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Tipping the scale: muscle versus fat

(2010) Matthew S. Rodeheffer   NATURE CELL BIOLOGY

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise

(2010) G. Valdez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining

(2010) J. C. Bruusgaard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myogenic response of human skeletal muscle to 12 weeks of resistance training at light loading intensity

(2010) A. L. Mackey et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Mitochondrial death effectors: Relevance to sarcopenia and disuse muscle atrophy

(2009) Emanuele Marzetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Wnt7a Activates the Planar Cell Polarity Pathway to Drive the Symmetric Expansion of Satellite Stem Cells

(2009) Fabien Le Grand et al.   Cell Stem Cell

Local NSAID infusion inhibits satellite cell proliferation in human skeletal muscle after eccentric exercise

(2009) U. R. Mikkelsen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Skeletal Muscle Hypertrophy Following Resistance Training Is Accompanied by a Fiber Type-Specific Increase in Satellite Cell Content in Elderly Men

(2009) L. B. Verdijk et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Interleukin-6 Is an Essential Regulator of Satellite Cell-Mediated Skeletal Muscle Hypertrophy

(2008) Antonio L. Serrano et al.   Cell Metabolism

Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysis

(2008) John K. Petrella et al.   JOURNAL OF APPLIED PHYSIOLOGY

Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging muscle-lengthening contractions in humans

(2008) Bryon R. McKay et al.   JOURNAL OF PHYSIOLOGY-LONDON

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE