Fibro–Adipogenic Progenitors Cross-Talk in Skeletal Muscle: The Social Network

Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age‐related muscle wasting

(2019) Peng Zhang et al.   Journal of Cachexia Sarcopenia and Muscle

The alarmins IL-1 and IL-33 differentially regulate the functional specialisation of Foxp3+ regulatory T cells during mucosal inflammation

(2019) Fernando Alvarez et al.   Mucosal Immunology

High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations

(2019) Lorenzo Giordani et al.   MOLECULAR CELL

Denervation-induced skeletal muscle fibrosis is mediated by CTGF/CCN2 independently of TGF-β

(2019) Daniela L. Rebolledo et al.   MATRIX BIOLOGY

Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors

(2019) Laura Lukjanenko et al.   Cell Stem Cell

Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle

(2019) Michael N. Wosczyna et al.   Cell Reports

The Mechanical Stimulation of Myotubes Counteracts the Effects of Tumor-Derived Factors Through the Modulation of the Activin/Follistatin Ratio

(2019) Alexandra Baccam et al.   Frontiers in Physiology

Interleukin-15 facilitates muscle regeneration through modulation of fibro/adipogenic progenitors

(2018) Xia Kang et al.   Cell Communication and Signaling

A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration

(2018) Michael N. Wosczyna et al.   DEVELOPMENTAL CELL

PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration

(2018) Gabriele Dammone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CCN4/WISP1 controls cutaneous wound healing by modulating proliferation, migration and ECM expression in dermal fibroblasts via α5β1 and TNFα

(2018) Mitsuaki Ono et al.   MATRIX BIOLOGY

Denervation-activated STAT3–IL-6 signalling in fibro-adipogenic progenitors promotes myofibres atrophy and fibrosis

(2018) Luca Madaro et al.   NATURE CELL BIOLOGY

Tregcells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration

(2018) Marisella Panduro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva

(2018) John B. Lees-Shepard et al.   Nature Communications

Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control

(2018) Tatiane Gorski et al.   Journal of Cachexia Sarcopenia and Muscle

Inhibition of the Activin Receptor Type-2B Pathway Restores Regenerative Capacity in Satellite Cell-Depleted Skeletal Muscle

(2018) Luigi Formicola et al.   Frontiers in Physiology

Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy

(2018) Barbora Malecova et al.   Nature Communications

Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling

(2018) Mayank Verma et al.   Cell Stem Cell

Orienting Muscle Stem Cells for Regeneration in Homeostasis, Aging, and Disease

(2018) Peter Feige et al.   Cell Stem Cell

Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration

(2018) Matthew J. Carr et al.   Cell Stem Cell

Fibro-Adipogenic Remodeling of the Diaphragm in Obesity-Associated Respiratory Dysfunction

(2018) Eric D. Buras et al.   DIABETES

Regulatory T cells were recruited by CCL3 to promote cryo-injured muscle repair

(2018) Chaoqi Zhang et al.   IMMUNOLOGY LETTERS

IL-1β- and IL-4-polarized macrophages have opposite effects on adipogenesis of intramuscular fibro-adipogenic progenitors in humans

(2018) C. Moratal et al.   Scientific Reports

AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy

(2018) Gaëtan Juban et al.   Cell Reports

IL-10 prevents aging-associated inflammation and insulin resistance in skeletal muscle

(2017) Sezin Dagdeviren et al.   FASEB JOURNAL

ACL injury reduces satellite cell abundance and promotes fibrogenic cell expansion within skeletal muscle

(2017) Christopher S. Fry et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Expression levels of TGF-β1 and CTGF are associated with the severity of Duchenne muscular dystrophy

(2017) Yanmin Song et al.   Experimental and Therapeutic Medicine

Short-term disuse promotes fatty acid infiltration into skeletal muscle

(2017) Allan F. Pagano et al.   Journal of Cachexia Sarcopenia and Muscle

HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway

(2017) Mariela Natacha González et al.   Skeletal Muscle

Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis

(2016) Osvaldo Contreras et al.   CELL AND TISSUE RESEARCH

Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells

(2016) Wilson Kuswanto et al.   IMMUNITY

Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis

(2016) Alisa A. Mueller et al.   NATURE

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

TGF-β Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis

(2016) Michael R. Davies et al.   PLoS One

Pharmacological blockage of fibro/adipogenic progenitor expansion and suppression of regenerative fibrogenesis is associated with impaired skeletal muscle regeneration

(2016) Daniela Fiore et al.   Stem Cell Research

KLF7 Regulates Satellite Cell Quiescence in Response to Extracellular Signaling

(2016) Xiaobin Wang et al.   STEM CELLS

WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling

(2015) Azusa Maeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

(2015) Dario R Lemos et al.   NATURE MEDICINE

FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration

(2015) Alessandra Castiglioni et al.   PLoS One

Glucocorticoids increase adipocytes in muscle by affecting IL-4 regulated FAP activity

(2014) Yanjun Dong et al.   FASEB JOURNAL

HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles

(2014) V. Saccone et al.   GENES & DEVELOPMENT

Dystrophic mdx mice develop severe cardiac and respiratory dysfunction following genetic ablation of the anti-inflammatory cytokine IL-10

(2014) Yuko Nitahara-Kasahara et al.   HUMAN MOLECULAR GENETICS

IL-33 Is an Unconventional Alarmin That Stimulates IL-2 Secretion by Dendritic Cells To Selectively Expand IL-33R/ST2+Regulatory T Cells

(2014) Benjamin M. Matta et al.   JOURNAL OF IMMUNOLOGY

STAT3 signaling controls satellite cell expansion and skeletal muscle repair

(2014) Matthew Timothy Tierney et al.   NATURE MEDICINE

Long-term administration of the TNF blocking drug Remicade (cV1q) to mdx mice reduces skeletal and cardiac muscle fibrosis, but negatively impacts cardiac function

(2014) N.V. Ermolova et al.   NEUROMUSCULAR DISORDERS

A Wnt-TGF 2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice

(2014) S. Biressi et al.   Science Translational Medicine

Regulatory T cells suppress muscle inflammation and injury in muscular dystrophy

(2014) S. A. Villalta et al.   Science Translational Medicine

TGF-β Activation and Function in Immunity

(2013) Mark A. Travis et al.   Annual Review of Immunology

A Special Population of Regulatory T Cells Potentiates Muscle Repair

(2013) Dalia Burzyn et al.   CELL

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

(2013) Jose E. Heredia et al.   CELL

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

(2013) Chiara Mozzetta et al.   EMBO Molecular Medicine

Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword?

(2013) Pura Muñoz-Cánoves et al.   FEBS Journal

Interleukin 33 as a Mechanically Responsive Cytokine Secreted by Living Cells

(2012) Rahul Kakkar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

(2012) Catherine E. Winbanks et al.   JOURNAL OF CELL BIOLOGY

IL-10 Triggers Changes in Macrophage Phenotype That Promote Muscle Growth and Regeneration

(2012) B. Deng et al.   JOURNAL OF IMMUNOLOGY

Allergic host defences

(2012) Noah W. Palm et al.   NATURE

Functionally Convergent White Adipogenic Progenitors of Different Lineages Participate in a Diffused System Supporting Tissue Regeneration

(2012) Dario R. Lemos et al.   STEM CELLS

Stem cells in the hood: the skeletal muscle niche

(2012) Alice Pannérec et al.   TRENDS IN MOLECULAR MEDICINE

Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease

(2011) Wenjun Ouyang et al.   Annual Review of Immunology

Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration

(2011) M. M. Murphy et al.   DEVELOPMENT

TGF-β signaling in fibrosis

(2011) Anna Biernacka et al.   GROWTH FACTORS

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

(2011) A. Uezumi et al.   JOURNAL OF CELL SCIENCE

Evolution of Th2 Immunity: A Rapid Repair Response to Tissue Destructive Pathogens

(2011) Judith E. Allen et al.   PLoS Pathogens

Regulatory interactions between muscle and the immune system during muscle regeneration

(2010) James G. Tidball et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

TNF/p38α/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration

(2010) Daniela Palacios et al.   Cell Stem Cell

Regulation and dysregulation of fibrosis in skeletal muscle

(2010) Antonio L. Serrano et al.   EXPERIMENTAL CELL RESEARCH

Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype

(2010) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity

(2010) Mitsuaki Ono et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Blockade of TNF in vivo using cV1q antibody reduces contractile dysfunction of skeletal muscle in response to eccentric exercise in dystrophic mdx and normal mice

(2010) A.T. Piers et al.   NEUROMUSCULAR DISORDERS

Possible implication of satellite cells in regenerative motoneuritogenesis: HGF upregulates neural chemorepellent Sema3A during myogenic differentiation

(2009) Ryuichi Tatsumi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle

(2009) E.-G. Hong et al.   DIABETES

Imatinib attenuates skeletal muscle dystrophy in mdx mice

(2009) Ping Huang et al.   FASEB JOURNAL

Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease

(2009) Louise R. Rodino-Klapac et al.   MUSCLE & NERVE

Myostatin Inhibition in Muscle, but Not Adipose Tissue, Decreases Fat Mass and Improves Insulin Sensitivity

(2009) Tingqing Guo et al.   PLoS One

Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates

(2009) J. Kota et al.   Science Translational Medicine

Interleukin-6 Is an Essential Regulator of Satellite Cell-Mediated Skeletal Muscle Hypertrophy

(2008) Antonio L. Serrano et al.   Cell Metabolism

Physical exercise improves plasmatic levels of IL-10, left ventricular end-diastolic pressure, and muscle lipid peroxidation in chronic heart failure rats

(2008) R. B. Nunes et al.   JOURNAL OF APPLIED PHYSIOLOGY

Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells

(2008) Morgan E. Carlson et al.   NATURE

Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6

(2008) Bente K. Pedersen et al.   PHYSIOLOGICAL REVIEWS

Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice

(2007) Masashi Nakatani et al.   FASEB JOURNAL