The role of SIRT1 in skeletal muscle function and repair of older mice

Muscle function decline and mitochondria changes in middle age precede sarcopenia in mice

(2018) Andrea del Campo et al.   Aging-US

Voluntary wheel running increases satellite cell abundance and improves recovery from disuse in gastrocnemius muscles from mice

(2018) Matthew J. Brooks et al.   JOURNAL OF APPLIED PHYSIOLOGY

Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus

(2018) Kirsten Thomsen et al.   NEUROBIOLOGY OF AGING

Circulating Mitochondrial DNA at the Crossroads of Mitochondrial Dysfunction and Inflammation During Aging and Muscle Wasting Disorders

(2018) Anna Picca et al.   REJUVENATION RESEARCH

Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis

(2018) Francesca Pala et al.   JOURNAL OF CELL SCIENCE

Mitochondria Initiate and Regulate Sarcopenia

(2017) Stephen E. Alway et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats

(2017) Hideyuki Takahashi et al.   EXPERIMENTAL GERONTOLOGY

Dietary resveratrol confers apoptotic resistance to oxidative stress in myoblasts

(2017) Satoshi Haramizu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Resveratrol Enhances Exercise-Induced Cellular and Functional Adaptations of Skeletal Muscle in Older Men and Women

(2017) Stephen E Alway et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The role of resveratrol on skeletal muscle cell differentiation and myotube hypertrophy during glucose restriction

(2017) Hannah F. Dugdale et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Ethical guidelines for publishing in the journal of cachexia, sarcopenia and muscle: update 2017

(2017) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Suppression of Myostatin Stimulates Regenerative Potential of Injured Antigravitational Soleus Muscle in Mice under Unloading Condition

(2016) Yoshitaka Ohno et al.   International Journal of Medical Sciences

Regenerative decline of stem cells in sarcopenia

(2016) Pedro Sousa-Victor et al.   MOLECULAR ASPECTS OF MEDICINE

The Mitochondrial Basis of Aging

(2016) Nuo Sun et al.   MOLECULAR CELL

Notch Signaling Rescues Loss of Satellite Cells Lacking Pax7 and Promotes Brown Adipogenic Differentiation

(2016) Alessandra Pasut et al.   Cell Reports

p53 in the DNA-Damage-Repair Process

(2016) Ashley B. Williams et al.   Cold Spring Harbor Perspectives in Medicine

Dysregulation of SIRT-1 in aging mice increases skeletal muscle fatigue by a PARP-1-dependent mechanism

(2016) Junaith S. Mohamed et al.   Aging-US

Age-dependent changes in mitochondrial morphology and volume are not predictors of lifespan

(2016) Saroj G. Regmi et al.   Aging-US

Cardiac and mitochondrial dysfunction following acute pulmonary exposure to mountaintop removal mining particulate matter

(2015) Cody E. Nichols et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

(2015) James G. Ryall et al.   Cell Stem Cell

Isolation of skeletal muscle stem cells by fluorescence-activated cell sorting

(2015) Ling Liu et al.   Nature Protocols

Overexpression of SIRT1 in Rat Skeletal Muscle Does Not Alter Glucose Induced Insulin Resistance

(2015) Amanda E. Brandon et al.   PLoS One

Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS)

(2014) A. J. Cruz-Jentoft et al.   AGE AND AGEING

Functional deficiencies of subsarcolemmal mitochondria in the type 2 diabetic human heart

(2014) Tara L. Croston et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Muscle-Specific SIRT1 Gain-of-Function Increases Slow-Twitch Fibers and Ameliorates Pathophysiology in a Mouse Model of Duchenne Muscular Dystrophy

(2014) Angeliki Chalkiadaki et al.   PLoS Genetics

Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics

(2013) Emanuele Marzetti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models

(2013) F. Demontis et al.   Disease Models & Mechanisms

The decline in skeletal muscle mass with aging is mainly attributed to a reduction in type II muscle fiber size

(2013) Rachel Nilwik et al.   EXPERIMENTAL GERONTOLOGY

Mitochondrial dysfunction and sarcopenia of aging: From signaling pathways to clinical trials

(2013) Emanuele Marzetti et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

SIRT1 Protein, by Blocking the Activities of Transcription Factors FoxO1 and FoxO3, Inhibits Muscle Atrophy and Promotes Muscle Growth

(2013) Donghoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Emerging Role of p53 in Exercise Metabolism

(2013) Jonathan D. Bartlett et al.   SPORTS MEDICINE

M-cadherin-inhibited phosphorylation of ß-catenin augments differentiation of mouse myoblasts

(2012) Yan Wang et al.   CELL AND TISSUE RESEARCH

Nicotinamide-induced Mitophagy

(2012) So-young Jang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rapid Determination of Myosin Heavy Chain Expression in Rat, Mouse, and Human Skeletal Muscle Using Multicolor Immunofluorescence Analysis

(2012) Darin Bloemberg et al.   PLoS One

MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging

(2011) Michael S. Lustgarten et al.   AGING CELL

Sirtuin 1 regulates skeletal myoblast survival and enhances differentiation in the presence of resveratrol

(2011) Amarjit Saini et al.   EXPERIMENTAL PHYSIOLOGY

Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged mice

(2011) Michael J. Ryan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sirtuin 1 (SIRT1) Deacetylase Activity Is Not Required for Mitochondrial Biogenesis or Peroxisome Proliferator-activated Receptor-γ Coactivator-1α (PGC-1α) Deacetylation following Endurance Exercise

(2011) Andrew Philp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long-Term Supplementation With Resveratrol Alleviates Oxidative Stress but Does Not Attenuate Sarcopenia in Aged Mice

(2011) Janna R. Jackson et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

(2011) Nady Braidy et al.   PLoS One

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny

(2010) Kenneth Day et al.   DEVELOPMENTAL BIOLOGY

Reduced Satellite Cell Numbers and Myogenic Capacity in Aging Can Be Alleviated by Endurance Exercise

(2010) Gabi Shefer et al.   PLoS One

PGC-1  regulates a HIF2 -dependent switch in skeletal muscle fiber types

(2010) K. A. Rasbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced apoptotic propensity in diabetic cardiac mitochondria: influence of subcellular spatial location

(2009) Courtney L. Williamson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

SIRT1 Controls the Transcription of the Peroxisome Proliferator-activated Receptor-γ Co-activator-1α (PGC-1α) Gene in Skeletal Muscle through the PGC-1α Autoregulatory Loop and Interaction with MyoD

(2009) Ramon Amat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Caloric restriction, SIRT1 and longevity

(2009) Carles Cantó et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Diabetic cardiomyopathy-associated dysfunction in spatially distinct mitochondrial subpopulations

(2008) Erinne R. Dabkowski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sarcopenic obesity: definition, cause and consequences

(2008) Sari Stenholm et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Endurance exercise increases the SIRT1 and peroxisome proliferator-activated receptor γ coactivator-1α protein expressions in rat skeletal muscle

(2008) Masataka Suwa et al.   METABOLISM-CLINICAL AND EXPERIMENTAL