Investigating AKT activation and autophagy in immunoproteasome-deficient retinal cells

Emerging roles and regulation of MiT/TFE transcriptional factors

(2018) Min Yang et al.   Cell Communication and Signaling

Immunoproteasomes as a novel antiviral mechanism in rhinovirus-infected airways

(2018) Kris Genelyn Dimasuay et al.   CLINICAL SCIENCE

Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

(2017) Nady Golestaneh et al.   Cell Death & Disease

mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

(2017) Michela Palmieri et al.   Nature Communications

Lysosomal adaptation: How cells respond to lysosomotropic compounds

(2017) Shuyan Lu et al.   PLoS One

mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress

(2016) Young Sung Yun et al.   MOLECULAR CELL

Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration

(2016) Deborah A. Ferrington et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Immunoproteasome Deficiency Protects in the Retina after Optic Nerve Crush

(2015) Nathan J. Schuld et al.   PLoS One

A quick signal of starvation induced autophagy: Transcription versus post-translational modification of LC3

(2014) Md. Razaul Karim et al.   ANALYTICAL BIOCHEMISTRY

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling

(2014) Mallika Valapala et al.   Autophagy

Noncanonical Autophagy Promotes the Visual Cycle

(2013) Ji-Young Kim et al.   CELL

Selective Autophagy: Talking with the UPS

(2013) Caroline Park et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Historical landmarks of autophagy research

(2013) Yoshinori Ohsumi   CELL RESEARCH

Immunoproteasome Deficiency Modifies the Alternative Pathway of NFκB Signaling

(2013) Marcela Maldonado et al.   PLoS One

A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle

(2012) Yu-Chiang Lai et al.   BIOCHEMICAL JOURNAL

Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression

(2011) Muhan Chen et al.   CANCER CELL

Ubiquitin–proteasome pathway and cellular responses to oxidative stress

(2011) Fu Shang et al.   FREE RADICAL BIOLOGY AND MEDICINE

MK-2206, a Novel Allosteric Inhibitor of Akt, Synergizes with Gefitinib against Malignant Glioma via Modulating Both Autophagy and Apoptosis

(2011) Y. Cheng et al.   MOLECULAR CANCER THERAPEUTICS

Mice completely lacking immunoproteasomes show major changes in antigen presentation

(2011) Eleanor Z Kincaid et al.   NATURE IMMUNOLOGY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress

(2010) Ulrike Seifert et al.   CELL

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules

(2010) B. Guillaume et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunoproteasome responds to injury in the retina and brain

(2008) Deborah A. Ferrington et al.   JOURNAL OF NEUROCHEMISTRY