White matter alterations in Alzheimer’s disease without concomitant pathologies

Brain-derived and circulating vesicle profiles indicate neurovascular unit dysfunction in early Alzheimer's disease

(2019) Xavier Gallart-Palau et al.   BRAIN PATHOLOGY

Aβ oligomers promote oligodendrocyte differentiation and maturation via integrin β1 and Fyn kinase signaling

(2019) Tania Quintela-López et al.   Cell Death & Disease

Evidence of demyelination in mild cognitive impairment and dementia using a direct and specific magnetic resonance imaging measure of myelin content

(2018) Mustapha Bouhrara et al.   Alzheimers & Dementia

Myelin changes at the early stage of 5XFAD mice

(2018) Lihua Gu et al.   BRAIN RESEARCH BULLETIN

Multimorbidity Is Associated with Preclinical Alzheimer’s Disease Neuroimaging Biomarkers

(2018) Aline Mendes et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Medical Comorbidity in Alzheimer’s Disease: A Nested Case-Control Study

(2018) Jen-Hung Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

White matter hyperintensities on MRI in dementia with Lewy bodies, Parkinson's disease with dementia, and Alzheimer's disease

(2018) Hideto Joki et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Association between Alzheimer’s disease pathogenesis and early demyelination and oligodendrocyte dysfunction

(2018) Xiao-Hong Sun et al.   Neural Regeneration Research

Review: Vascular dementia: clinicopathologic and genetic considerations

(2018) H. V. Vinters et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes

(2018) Sara E. Nasrabady et al.   Acta Neuropathologica Communications

Possible Retrogenesis Observed with Fiber Tracking: An Anteroposterior Pattern of White Matter Disintegrity in Normal Aging and Alzheimer's Disease

(2018) Junling Gao et al.   JOURNAL OF ALZHEIMERS DISEASE

Oligodendrogliopathy in neurodegenerative diseases with abnormal protein aggregates: The forgotten partner

(2018) Isidro Ferrer   PROGRESS IN NEUROBIOLOGY

Comorbidity Analysis between Alzheimer’s Disease and Type 2 Diabetes Mellitus (T2DM) Based on Shared Pathways and the Role of T2DM Drugs

(2017) Reagon Karki et al.   JOURNAL OF ALZHEIMERS DISEASE

Myelin content changes in probable Alzheimer's disease and mild cognitive impairment: Associations with age and severity of neuropsychiatric impairment

(2017) Eleftherios Kavroulakis et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

DNA damage in the oligodendrocyte lineage and its role in brain aging

(2017) Kai-Hei Tse et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The blood-brain barrier in Alzheimer's disease

(2017) Elena Zenaro et al.   NEUROBIOLOGY OF DISEASE

Microstructural white matter alterations in preclinical Alzheimer’s disease detected using free water elimination diffusion tensor imaging

(2017) Andrew R. Hoy et al.   PLoS One

Comorbidity and progression of late onset Alzheimer’s disease: A systematic review

(2017) Miriam L. Haaksma et al.   PLoS One

Axonal and myelinic pathology in 5xFAD Alzheimer’s mouse spinal cord

(2017) Tak-Ho Chu et al.   PLoS One

Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer’s disease

(2016) Raj N. Kalaria   ACTA NEUROPATHOLOGICA

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

(2016) Seonjoo Lee et al.   ANNALS OF NEUROLOGY

Post-mortem assessment in vascular dementia: advances and aspirations

(2016) Kirsty E. McAleese et al.   BMC Medicine

Vascular cognitive impairment neuropathology guidelines (VCING): the contribution of cerebrovascular pathology to cognitive impairment

(2016) Olivia A. Skrobot et al.   BRAIN

Decreased Regenerative Capacity of Oligodendrocyte Progenitor Cells (NG2-Glia) in the Ageing Brain: A Vicious Cycle of Synaptic Dysfunction, Myelin Loss and Neuronal Disruption?

(2016) Andrea Rivera et al.   Current Alzheimer Research

Update on Vascular Dementia

(2016) Ayesha Khan et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease

(2016) Timothy A. Couttas et al.   NEUROBIOLOGY OF AGING

Neuropathologic comorbidity and cognitive impairment in the Nun and Honolulu-Asia Aging Studies

(2016) Lon R. White et al.   NEUROLOGY

Contribution of the oligodendrocyte lineage to CNS repair and neurodegenerative pathologies

(2016) Reshmi Tognatta et al.   NEUROPHARMACOLOGY

PART is part of Alzheimer disease

(2015) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Oligodendrocytes and Alzheimer's disease

(2015) Zhiyou Cai et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Insights into White Matter Damage in Alzheimer's Disease: From Postmortem to in vivo Diffusion Tensor MRI Studies

(2015) Francesca Caso et al.   Neurodegenerative Diseases

MAG, myelin and overcoming growth inhibition in the CNS

(2015) Lisa McKerracher et al.   Frontiers in Molecular Neuroscience

Cortical tau load is associated with white matter hyperintensities

(2015) Kirsty E. McAleese et al.   Acta Neuropathologica Communications

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

Age-Associated White Matter Lesions: The MRC Cognitive Function and Ageing Study

(2014) Stephen B. Wharton et al.   BRAIN PATHOLOGY

Oxidative Glial Cell Damage Associated with White Matter Lesions in the Aging Human Brain

(2014) Sufana Al-Mashhadi et al.   BRAIN PATHOLOGY

Blood-Brain Barrier Dysfunction and Cerebral Small Vessel Disease (Arteriolosclerosis) in Brains of Older People

(2014) Leslie R. Bridges et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Comorbidity in Dementia: Update of an Ongoing Autopsy Study

(2014) Shino Magaki et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

White matter changes in preclinical Alzheimer's disease: a magnetic resonance imaging-diffusion tensor imaging study on cognitively normal older people with positive amyloid β protein 42 levels

(2014) José Luis Molinuevo et al.   NEUROBIOLOGY OF AGING

The myelin membrane-associated enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase: on a highway to structure and function

(2014) Arne Raasakka et al.   Neuroscience Bulletin

Contemplating Alzheimer’s Disease and the Contribution of White Matter Hyperintensities

(2013) Adam M. Brickman   Current Neurology and Neuroscience Reports

The role of myelin and oligodendrocytes in axonal energy metabolism

(2013) Aiman S Saab et al.   CURRENT OPINION IN NEUROBIOLOGY

White matter abnormalities associated with Alzheimer’s disease and mild cognitive impairment: a critical review of MRI studies

(2013) Marcia Radanovic et al.   Expert Review of Neurotherapeutics

Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease

(2013) Michelle A Erickson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Age-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study

(2013) Naruhiko Sahara et al.   NEUROBIOLOGY OF AGING

Neuropathologic basis of white matter hyperintensity accumulation with advanced age

(2013) D. Erten-Lyons et al.   NEUROLOGY

Disconnected aging: Cerebral white matter integrity and age-related differences in cognition

(2013) I.J. Bennett et al.   NEUROSCIENCE

MYRF Is a Membrane-Associated Transcription Factor That Autoproteolytically Cleaves to Directly Activate Myelin Genes

(2013) Helena Bujalka et al.   PLOS BIOLOGY

White matter tract integrity metrics reflect the vulnerability of late-myelinating tracts in Alzheimer's disease

(2013) Andreana Benitez et al.   NeuroImage-Clinical

NG2 cells, a new trail for Alzheimer’s disease mechanisms?

(2013) Henrietta M Nielsen et al.   Acta Neuropathologica Communications

White matter imaging changes in subjective and mild cognitive impairment

(2012) Per Selnes et al.   Alzheimers & Dementia

Decreased Oligodendrocyte Nuclear Diameter in Alzheimer's Disease and Lewy Body Dementia

(2012) Eva Gagyi et al.   BRAIN PATHOLOGY

Regional and cell-type specific distribution of HDAC2 in the adult mouse brain

(2012) Zhi-Gang Yao et al.   Brain Structure & Function

Vascular dementia: Different forms of vessel disorders contribute to the development of dementia in the elderly brain

(2012) Dietmar Rudolf Thal et al.   EXPERIMENTAL GERONTOLOGY

Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men

(2012) Gwendolyn Behrendt et al.   GLIA

Differential cell proliferation in the cortex of the appsweps1de9 alzheimer's disease mouse model

(2012) Willem Kamphuis et al.   GLIA

Myelin Gene Regulatory Factor Is Required for Maintenance of Myelin and Mature Oligodendrocyte Identity in the Adult CNS

(2012) M. Koenning et al.   JOURNAL OF NEUROSCIENCE

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Defining Alzheimer as a common age-related neurodegenerative process not inevitably leading to dementia

(2012) Isidro Ferrer   PROGRESS IN NEUROBIOLOGY

Age-related changes in human and non-human primate white matter: from myelination disturbances to cognitive decline

(2011) Steven G. Kohama et al.   AGE

Mass and relative elution time profiling: two-dimensional analysis of sphingolipids in Alzheimer's disease brains

(2011) Leila Hejazi et al.   BIOCHEMICAL JOURNAL

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Regulation of Oligodendrocyte Development and Myelination by Glucose and Lactate

(2011) J. E. Rinholm et al.   JOURNAL OF NEUROSCIENCE

Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer’s disease, and dementia with Lewy bodies

(2010) Masafumi Ihara et al.   ACTA NEUROPATHOLOGICA

Vascular pathology in the aged human brain

(2010) Lea Tenenholz Grinberg et al.   ACTA NEUROPATHOLOGICA

Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target

(2010) Maya K. Desai et al.   AMERICAN JOURNAL OF PATHOLOGY

CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

(2010) Malgorzata Zawadzka et al.   Cell Stem Cell

Emerging functions of myelin-associated proteins during development, neuronal plasticity, and neurodegeneration

(2010) Franc Llorens et al.   FASEB JOURNAL

Amyloid Efflux Transporter Expression at the Blood-Brain Barrier Declines in Normal Aging

(2010) Gerald D. Silverberg et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

NG2 Glia Generate New Oligodendrocytes But Few Astrocytes in a Murine Experimental Autoimmune Encephalomyelitis Model of Demyelinating Disease

(2010) R. B. Tripathi et al.   JOURNAL OF NEUROSCIENCE

Cognitive impairment of vascular origin: Neuropathology of cognitive impairment of vascular origin

(2010) Isidre Ferrer   JOURNAL OF THE NEUROLOGICAL SCIENCES

Review: Cerebral microvascular pathology in ageing and neurodegeneration

(2010) W. R. Brown et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

White matter hyperintensities and changes in white matter integrity in patients with Alzheimer’s disease

(2010) Liya Wang et al.   NEURORADIOLOGY

Myelin Gene Regulatory Factor Is a Critical Transcriptional Regulator Required for CNS Myelination

(2009) Ben Emery et al.   CELL

Amyloid Deposition and Influx Transporter Expression at the Blood-Brain Barrier Increase in Normal Aging

(2009) Gerald D. Silverberg et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Myelin Proteomics: Molecular Anatomy of an Insulating Sheath

(2009) Olaf Jahn et al.   MOLECULAR NEUROBIOLOGY

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction

(2009) Feng Ye et al.   NATURE NEUROSCIENCE

Alzheimer's disease as homeostatic responses to age-related myelin breakdown

(2009) George Bartzokis   NEUROBIOLOGY OF AGING

Cerebral amyloid angiopathy and its relationship to Alzheimer’s disease

(2008) Dietmar Rudolf Thal et al.   ACTA NEUROPATHOLOGICA

Heterogeneity of white matter hyperintensities in Alzheimer's disease: post-mortem quantitative MRI and neuropathology

(2008) A. A. Gouw et al.   BRAIN

Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

(2008) Maya K. Desai et al.   GLIA

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Regional white matter volume differences in nondemented aging and Alzheimer's disease

(2008) D SALAT et al.   NEUROIMAGE

Spatial Distribution of White-Matter Hyperintensities in Alzheimer Disease, Cerebral Amyloid Angiopathy, and Healthy Aging

(2008) Christopher M. Holland et al.   STROKE