Oligodendrocytes and Alzheimer's disease

Alzheimer's Disease is Incurable but Preventable

(2017) Jack C. de la Torre   JOURNAL OF ALZHEIMERS DISEASE

Myeloid microvesicles in cerebrospinal fluid are associated with myelin damage and neuronal loss in mild cognitive impairment and Alzheimer disease

(2014) Federica Agosta et al.   ANNALS OF NEUROLOGY

Hippocampal metabolomics using ultrahigh-resolution mass spectrometry reveals neuroinflammation from Alzheimer’s disease in CRND8 mice

(2013) Shuhai Lin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog

(2013) Swetlana Sirko et al.   Cell Stem Cell

Ischemia-Induced Neuroinflammation Is Associated with Disrupted Development of Oligodendrocyte Progenitors in a Model of Periventricular Leukomalacia

(2013) Sina Falahati et al.   DEVELOPMENTAL NEUROSCIENCE

Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer's disease

(2013) Zhiyou Cai et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Adenomatous Polyposis Coli Regulates Oligodendroglial Development

(2013) J. Lang et al.   JOURNAL OF NEUROSCIENCE

Modulation of FGF receptor signaling as an intervention and potential therapy for myelin breakdown in Alzheimer’s disease

(2013) Jia-Su Li et al.   MEDICAL HYPOTHESES

The Triggering Receptor Expressed on Myeloid Cells 2: “TREM-ming” the Inflammatory Component Associated with Alzheimer's Disease

(2013) Troy T. Rohn   Oxidative Medicine and Cellular Longevity

Age-Dependent Astroglial Vulnerability to Hypoxia and Glutamate: The Role for Erythropoietin

(2013) Ali Lourhmati et al.   PLoS One

WIN55,212-2 protects oligodendrocyte precursor cells in stroke penumbra following permanent focal cerebral ischemia in rats

(2012) Jing Sun et al.   ACTA PHARMACOLOGICA SINICA

Myelin breakdown mediates age-related slowing in cognitive processing speed in healthy elderly men

(2012) Po H. Lu et al.   BRAIN AND COGNITION

Decreased Oligodendrocyte Nuclear Diameter in Alzheimer's Disease and Lewy Body Dementia

(2012) Eva Gagyi et al.   BRAIN PATHOLOGY

WIN55, 212-2 promotes differentiation of oligodendrocyte precursor cells and improve remyelination through regulation of the phosphorylation level of the ERK 1/2 via cannabinoid receptor 1 after stroke-induced demyelination

(2012) Jing Sun et al.   BRAIN RESEARCH

Roles of Glycogen Synthase Kinase 3 in Alzheimer’s Disease

(2012) Zhiyou Cai et al.   Current Alzheimer Research

Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men

(2012) Gwendolyn Behrendt et al.   GLIA

Differential cell proliferation in the cortex of the appsweps1de9 alzheimer's disease mouse model

(2012) Willem Kamphuis et al.   GLIA

Synaptic alterations in the rTg4510 mouse model of tauopathy

(2012) Katherine J. Kopeikina et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction in a Mouse Model That Exhibits Age-Dependent Progression of Alzheimer's Disease-Related Pathology

(2012) A. D. Bachstetter et al.   JOURNAL OF NEUROSCIENCE

Ferritin Stimulates Oligodendrocyte Genesis in the Adult Spinal Cord and Can Be Transferred from Macrophages to NG2 Cells In Vivo

(2012) D. L. Schonberg et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation and Common Mechanism in Alzheimer’s Disease and Prion Amyloidosis: Amyloid-Associated Proteins, Neuroinflammation and Neurofibrillary Degeneration

(2012) Annemieke J.M. Rozemuller et al.   Neurodegenerative Diseases

Nitric Oxide-Mediated Oxidative Damage and the Progressive Demise of Motor Neurons in ALS

(2012) Derek A. Drechsel et al.   NEUROTOXICITY RESEARCH

Neuropathological Similarities and Differences between Schizophrenia and Bipolar Disorder: A Flow Cytometric Postmortem Brain Study

(2012) Yoshitaka Hayashi et al.   PLoS One

Reduced Myelin Basic Protein and Actin-Related Gene Expression in Visual Cortex in Schizophrenia

(2012) Paul R. Matthews et al.   PLoS One

Alzheimer's Disease: Redox Dysregulation As a Common Denominator for Diverse Pathogenic Mechanisms

(2011) Rommy von Bernhardi et al.   ANTIOXIDANTS & REDOX SIGNALING

Synaptic Mitochondrial Pathology in Alzheimer's Disease

(2011) Heng Du et al.   ANTIOXIDANTS & REDOX SIGNALING

Myelin Restoration: Progress and Prospects for Human Cell Replacement Therapies

(2011) Gregory B. Potter et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Enhancing remyelination in disease--can we wrap it up?

(2011) M. R. Kotter et al.   BRAIN

Epigenetic Mechanisms in Alzheimer's Disease

(2011) M. Daniilidou et al.   CURRENT MEDICINAL CHEMISTRY

An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction

(2011) Maya K. Desai et al.   GLIA

Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease

(2011) Chia-Hsiung Chen et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Age-related slowing in cognitive processing speed is associated with myelin integrity in a very healthy elderly sample

(2011) Po H. Lu et al.   JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY

Mitochondria, oligodendrocytes and inflammation in bipolar disorder: Evidence from transcriptome studies points to intriguing parallels with multiple sclerosis

(2011) Christine Konradi et al.   NEUROBIOLOGY OF DISEASE

Oxidative Stress and β-Amyloid Protein in Alzheimer’s Disease

(2011) Zhiyou Cai et al.   NEUROMOLECULAR MEDICINE

Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer's disease

(2011) Cai Wang et al.   NEUROSCIENCE LETTERS

Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture

(2011) C J Garwood et al.   Cell Death & Disease

Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer’s disease, and dementia with Lewy bodies

(2010) Masafumi Ihara et al.   ACTA NEUROPATHOLOGICA

Focal demyelination in Alzheimer’s disease and transgenic mouse models

(2010) Stanislaw Mitew et al.   ACTA NEUROPATHOLOGICA

Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target

(2010) Maya K. Desai et al.   AMERICAN JOURNAL OF PATHOLOGY

Biomarkers of oxidative damage and inflammation in Alzheimer’s disease

(2010) Douglas Galasko et al.   Biomarkers in Medicine

Expression of oligodendrocyte and myelin genes is not altered in peripheral blood cells of patients with first-episode schizophrenia and bipolar disorder

(2010) Arantza Gutiérrez-Fernández et al.   BIPOLAR DISORDERS

Modulation of adult hippocampal neurogenesis during myelin-directed autoimmune neuroinflammation

(2010) Petra Huehnchen et al.   GLIA

Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early-Onset Form (Type I) and Demyelination in Late-Onset Form (Type II)

(2010) Lars Svennerholm et al.   JOURNAL OF NEUROCHEMISTRY

2,2′,4′-Trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice

(2010) Zhiyuan Zhu et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid β1–42 oligomer inhibits myelin sheet formation in vitro

(2010) Makoto Horiuchi et al.   NEUROBIOLOGY OF AGING

Preclinical Alzheimer disease: Brain oxidative stress, Aβ peptide and proteomics

(2010) Christopher D. Aluise et al.   NEUROBIOLOGY OF DISEASE

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

Mitotic Epitopes are Incorporated into Age-dependent Neurofibrillary Tangles in Niemann-Pick Disease Type C

(2009) Min Zhang et al.   BRAIN PATHOLOGY

Early Tau Pathology Involving the Septo-Hippocampal Pathway in a Tau Transgenic Model: Relevance to Alzheimers Disease

(2009) Karim Belarbi et al.   Current Alzheimer Research

Apoptotic mechanisms involved in neurodegenerative diseases: Experimental and therapeutic approaches

(2009) A. Camins et al.   METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY

Activated astroglia during chronic inflammation in Alzheimer's disease—Do they neglect their neurosupportive roles?

(2009) Stacey Fuller et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Alzheimer's disease as homeostatic responses to age-related myelin breakdown

(2009) George Bartzokis   NEUROBIOLOGY OF AGING

Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease

(2009) R. Sims et al.   NEUROSCIENCE LETTERS

Myelinated, synapsing cultures of murine spinal cord - validation as anin vitromodel of the central nervous system

(2008) C. E. Thomson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

(2008) Maya K. Desai et al.   GLIA

The biology of CNS remyelination

(2008) Robin J. M. Franklin et al.   JOURNAL OF NEUROLOGY

Lifespan trajectory of myelin integrity and maximum motor speed

(2008) George Bartzokis et al.   NEUROBIOLOGY OF AGING

The Abnormally Phosphorylated Tau Lesion of Early Alzheimer’s Disease

(2008) Ramasamy Thangavel et al.   NEUROCHEMICAL RESEARCH