Blood-Brain Barrier Dysfunction and Cerebral Small Vessel Disease (Arteriolosclerosis) in Brains of Older People

Outcome markers for clinical trials in cerebral amyloid angiopathy

(2014) Steven M Greenberg et al.   LANCET NEUROLOGY

Stroke-Induced Brain Parenchymal Injury Drives Blood–Brain Barrier Early Leakage Kinetics: A Combined in Vivo/in Vitro Study

(2013) Mélanie Kuntz et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The APOE ε4/ε4 Genotype Potentiates Vascular Fibrin(Ogen) Deposition in Amyloid-Laden Vessels in the Brains of Alzheimer's Disease Patients

(2013) Karin Hultman et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury

(2013) Ji Hae Seo et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuropathology of the blood–brain barrier and pharmaco-resistance in human epilepsy

(2012) Joan Y. W. Liu et al.   BRAIN

Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease

(2012) Jesse D. Sengillo et al.   BRAIN PATHOLOGY

Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease

(2012) Azeb Tadesse Argaw et al.   JOURNAL OF CLINICAL INVESTIGATION

Safety, tolerability, and antibody response of active Aβ immunotherapy with CAD106 in patients with Alzheimer's disease: randomised, double-blind, placebo-controlled, first-in-human study

(2012) Bengt Winblad et al.   LANCET NEUROLOGY

Investigation of the Role of FcγR and FcRn in mAb Distribution to the Brain

(2012) Lubna Abuqayyas et al.   MOLECULAR PHARMACEUTICS

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

(2012) Robert D. Bell et al.   NATURE

Blood–Brain Barrier Permeability and Long-Term Clinical and Imaging Outcomes in Cerebral Small Vessel Disease

(2012) Joanna M. Wardlaw et al.   STROKE

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation

(2012) Dimitrios Davalos et al.   Nature Communications

Heterogeneity in age-related white matter changes

(2011) Reinhold Schmidt et al.   ACTA NEUROPATHOLOGICA

Apolipoprotein E Regulates the Integrity of Tight Junctions in an Isoform-dependent Manner in anin VitroBlood-Brain Barrier Model

(2011) Kazuchika Nishitsuji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuropathologic evidence of endothelial changes in cerebral small vessel disease

(2011) M. O. Giwa et al.   NEUROLOGY

Cerebral subcortical small vessel disease and its relation to cognition in elderly subjects: a pathological study in the Oxford Project to Investigate Memory and Ageing (OPTIMA) cohort

(2011) A. Smallwood et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Alterations in the blood brain barrier in ageing cerebral cortex in relationship to Alzheimer-type pathology: A study in the MRC-CFAS population neuropathology cohort

(2011) Andrew P. Viggars et al.   NEUROSCIENCE LETTERS

Fibrinogen as a key regulator of inflammation in disease

(2011) Dimitrios Davalos et al.   Seminars in Immunopathology

Blood–Brain Barrier Permeability Abnormalities in Vascular Cognitive Impairment

(2011) Saeid Taheri et al.   STROKE

Amyloid-β Contributes to Blood–Brain Barrier Leakage in Transgenic Human Amyloid Precursor Protein Mice and in Humans With Cerebral Amyloid Angiopathy

(2011) Anika M.S. Hartz et al.   STROKE

Neuropathology after active Aβ42 immunotherapy: implications for Alzheimer’s disease pathogenesis

(2010) Delphine Boche et al.   ACTA NEUROPATHOLOGICA

Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges

(2010) Leonardo Pantoni   LANCET NEUROLOGY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Lacunar stroke is associated with diffuse blood-brain barrier dysfunction

(2009) Joanna M. Wardlaw et al.   ANNALS OF NEUROLOGY

Quantitative and Mechanistic Studies of Aβ Immunotherapy

(2009) Todd Golde et al.   CNS & Neurological Disorders-Drug Targets

Blood-brain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis

(2009) R Topakian et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Death-associated protein kinase (DAPK1) in cerebral cortex of late-onset Alzheimer's disease patients and aged controls

(2009) A. H. Hainsworth et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Cerebral Small Vessel Disease-Induced Apolipoprotein E Leakage Is Associated With Alzheimer Disease and the Accumulation of Amyloid β-Protein in Perivascular Astrocytes

(2008) Sabrina Utter et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neuropathologic correlates of white matter hyperintensities

(2008) V. G. Young et al.   NEUROLOGY

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis

(2007) Andrew J. Farrall et al.   NEUROBIOLOGY OF AGING