Defensive Driving: Directing HIV-1 Vaccine-Induced Humoral Immunity to the Mucosa with Chemokine Adjuvants

HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis

(2018) Saintedym Wills et al.   JOURNAL OF VIROLOGY

Complex immune correlates of protection in HIV-1 vaccine efficacy trials

(2017) Georgia D. Tomaras et al.   IMMUNOLOGICAL REVIEWS

Leukocyte Trafficking to the Small Intestine and Colon

(2016) Aida Habtezion et al.   GASTROENTEROLOGY

Peyer's patches: organizing B-cell responses at the intestinal frontier

(2016) Andrea Reboldi et al.   IMMUNOLOGICAL REVIEWS

Role of chemokine receptors and intestinal epithelial cells in the mucosal inflammation and tolerance

(2016) Neeraja Kulkarni et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HIV-1-Neutralizing IgA Detected in Genital Secretions of Highly HIV-1-Exposed Seronegative Women on Oral Preexposure Prophylaxis

(2016) Jennifer M. Lund et al.   JOURNAL OF VIROLOGY

Lessons from the RV144 Thai Phase III HIV-1 Vaccine Trial and the Search for Correlates of Protection

(2015) Jerome H. Kim et al.   Annual Review of Medicine

Immunization with HSV-2 gB-CCL19 Fusion Constructs Protects Mice against Lethal Vaginal Challenge

(2015) Yan Yan et al.   JOURNAL OF IMMUNOLOGY

Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1

(2015) Justin Pollara et al.   JOURNAL OF VIROLOGY

Evidence for a common mucosal immune system in the pig

(2015) Heather L. Wilson et al.   MOLECULAR IMMUNOLOGY

Interleukin (IL)-21 promotes intestinal IgA response to microbiota

(2015) A T Cao et al.   Mucosal Immunology

Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins and an influx of HIV-susceptible target cells

(2015) Kelly B Arnold et al.   Mucosal Immunology

Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge

(2015) M A Kutzler et al.   Mucosal Immunology

Immune correlates of vaccine protection against HIV-1 acquisition

(2015) Lawrence Corey et al.   Science Translational Medicine

Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: Complete protection of rhesus monkeys from mucosal SHIV challenge

(2015) Anton M. Sholukh et al.   VACCINE

CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes

(2015) Emma C. Mackley et al.   Nature Communications

Nonneutralizing Functional Antibodies: a New “Old” Paradigm for HIV Vaccines

(2014) Jean-Louis Excler et al.   Clinical and Vaccine Immunology

A role for CCL28–CCR3 in T-cell homing to the human upper airway mucosa

(2014) E Danilova et al.   Mucosal Immunology

Anti-HIV IgA isotypes

(2013) Jennifer D. Watkins et al.   AIDS

CCL19 and CCL28 Augment Mucosal and Systemic Immune Responses to HIV-1 gp140 by Mobilizing Responsive Immunocytes into Secondary Lymph Nodes and Mucosal Tissue

(2013) K. Hu et al.   JOURNAL OF IMMUNOLOGY

A “Prime-Pull” Vaccine Strategy Has a Modest Effect on Local and Systemic Antibody Responses to HIV gp140 in Mice

(2013) John S. Tregoning et al.   PLoS One

Teleost skin, an ancient mucosal surface that elicits gut-like immune responses

(2013) Z. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skin- and gut-homing molecules on human circulating γδ T cells and their dysregulation in inflammatory bowel disease

(2012) E. R. Mann et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Chemokines at mucosal barriers and their impact on HIV infection

(2012) Magali Rancez et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The Chemokine Superfamily Revisited

(2012) Albert Zlotnik et al.   IMMUNITY

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

(2012) Matthieu Perreau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A vaccine strategy that protects against genital herpes by establishing local memory T cells

(2012) Haina Shin et al.   NATURE

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

(2012) Barton F. Haynes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Generation of antigen-specific immunity following systemic immunization with DNA vaccine encoding CCL25 chemokine immunoadjuvant

(2012) Noshin Kathuria et al.   Human Vaccines & Immunotherapeutics

Functional Flexibility of Intestinal IgA – Broadening the Fine Line

(2012) Emma Slack et al.   Frontiers in Immunology

Electroporation delivery of DNA vaccines: prospects for success

(2011) Niranjan Y Sardesai et al.   CURRENT OPINION IN IMMUNOLOGY

CXCR3 in T cell function

(2011) Joanna R. Groom et al.   EXPERIMENTAL CELL RESEARCH

The Chemokine Receptor CCR9 Is Required for the T-Cell–Mediated Regulation of Chronic Ileitis in Mice

(2011) Joshua D. Wermers et al.   GASTROENTEROLOGY

Gut-Tropic T Cells That Express Integrin α4β7 and CCR9 Are Required for Induction of Oral Immune Tolerance in Mice

(2011) Barbara Cassani et al.   GASTROENTEROLOGY

Female genital tract immunity: distinct immunological challenges for vaccine development

(2011) Rajesh K. Naz   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

CCL25/CCR9 Interactions Regulate Large Intestinal Inflammation in a Murine Model of Acute Colitis

(2011) Marc-Andre Wurbel et al.   PLoS One

The puzzle of intestinal lamina propria dendritic cells and macrophages

(2010) Oliver Pabst et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Anti-HIV Activity in Cervical-Vaginal Secretions from HIV-Positive and -Negative Women Correlate with Innate Antimicrobial Levels and IgG Antibodies

(2010) Mimi Ghosh et al.   PLoS One

CCR6 ligands inhibit HIV by inducing APOBEC3G

(2009) M. K. Lafferty et al.   BLOOD

Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo

(2009) M A Kutzler et al.   GENE THERAPY

Chemokine Expression Patterns in the Systemic and Genital Tract Compartments are Associated with HIV-1 Infection in Women from Benin

(2009) Julie Lajoie et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human IgA-secreting cells induced by intestinal, but not systemic, immunization respond to CCL25 (TECK) and CCL28 (MEC)

(2008) Patrik Sundström et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

DNA vaccines: developing new strategies to enhance immune responses

(2008) Shaheed A. Abdulhaqq et al.   IMMUNOLOGIC RESEARCH

Differentiation and homing of IgA-secreting cells

(2008) J R Mora et al.   Mucosal Immunology

DNA vaccines: ready for prime time?

(2008) Michele A. Kutzler et al.   NATURE REVIEWS GENETICS

Molecular cloning and functional characterization of porcine CCL28: Possible involvement in homing of IgA antibody secreting cells into the mammary gland

(2007) Mustapha Berri et al.   MOLECULAR IMMUNOLOGY