Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide

Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation

(2018) Thomas C.T. Michaels et al.   Annual Review of Physical Chemistry

Secondary nucleation in amyloid formation

(2018) Mattias Törnquist et al.   CHEMICAL COMMUNICATIONS

Reaction rate theory for supramolecular kinetics: application to protein aggregation

(2018) Thomas C. T. Michaels et al.   MOLECULAR PHYSICS

Inhibition of amyloid beta fibril formation by monomeric human transthyretin

(2018) Kanchan Garai et al.   PROTEIN SCIENCE

Mechanisms and rates of nucleation of amyloid fibrils

(2017) Cheng-Tai Lee et al.   JOURNAL OF CHEMICAL PHYSICS

Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes

(2017) Wei Qiang et al.   NATURE

Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation

(2016) Anđela Šarić et al.   JOURNAL OF CHEMICAL PHYSICS

Atomic Resolution Structure of Monomorphic Aβ42 Amyloid Fibrils

(2016) Michael T. Colvin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Physical determinants of the self-replication of protein fibrils

(2016) Anđela Šarić et al.   Nature Physics

Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril

(2016) Marielle Aulikki Wälti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescent Filter-Trap Assay for Amyloid Fibril Formation Kinetics in Complex Solutions

(2015) Irem Nasir et al.   ACS Chemical Neuroscience

Secondary Crystal Nucleation: Nuclei Breeding Factory Uncovered

(2015) Jamshed Anwar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42

(2015) Olga Szczepankiewicz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation

(2015) Serene W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation

(2015) Risto Cukalevski et al.   Chemical Science

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

2014 Alzheimer's disease facts and figures

(2014)   Alzheimers & Dementia

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crucial role of nonspecific interactions in amyloid nucleation

(2014) Anđela Šarić et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

The non-classical nucleation of crystals: microscopic mechanisms and applications to molecular crystals, ice and calcium carbonate

(2012) R P Sear   INTERNATIONAL MATERIALS REVIEWS

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

The two-step mechanism of nucleation of crystals in solution

(2010) Peter G. Vekilov   Nanoscale

A causative link between the structure of aberrant protein oligomers and their toxicity

(2010) Silvia Campioni et al.   Nature Chemical Biology

A facile method for expression and purification of the Alzheimer’s disease-associated amyloid β-peptide

(2009) Dominic M. Walsh et al.   FEBS Journal

Determination of the Free Energy Landscape of α-Synuclein Using Spin Label Nuclear Magnetic Resonance Measurements

(2009) Jane R. Allison et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oligomeric amyloid   associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

(2009) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Analytical Solution to the Kinetics of Breakable Filament Assembly

(2009) T. P. J. Knowles et al.   SCIENCE