Physical determinants of the self-replication of protein fibrils

A coarse grained protein model with internal degrees of freedom. Application to α-synuclein aggregation

(2016) Ioana M. Ilie et al.   JOURNAL OF CHEMICAL PHYSICS

Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide

(2016) Georg Meisl et al.   Scientific Reports

Dynamics of protein aggregation and oligomer formation governed by secondary nucleation

(2015) Thomas C. T. Michaels et al.   JOURNAL OF CHEMICAL PHYSICS

CAMELOT: A machine learning approach for coarse-grained simulations of aggregation of block-copolymeric protein sequences

(2015) Kiersten M. Ruff et al.   JOURNAL OF CHEMICAL PHYSICS

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

(2015) Céline Galvagnion et al.   Nature Chemical Biology

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Coarse-Grained Model for Polyglutamine Aggregation Modulated by Amphipathic Flanking Sequences

(2014) Kiersten M. Ruff et al.   BIOPHYSICAL JOURNAL

Fiber-Dependent and -Independent Toxicity of Islet Amyloid Polypeptide

(2014) Diana E. Schlamadinger et al.   BIOPHYSICAL JOURNAL

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crucial role of nonspecific interactions in amyloid nucleation

(2014) Anđela Šarić et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-replicating colloidal clusters

(2014) Zorana Zeravcic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

(2014) Georg Meisl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution conditions determine the relative importance of nucleation and growth processes in  -synuclein aggregation

(2014) A. K. Buell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic structure and hierarchical assembly of a cross-  amyloid fibril

(2013) A. W. P. Fitzpatrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detailed Analysis of the Energy Barriers for Amyloid Fibril Growth

(2012) Alexander K. Buell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Connecting Macroscopic Observables and Microscopic Assembly Events in Amyloid Formation Using Coarse Grained Simulations

(2012) Noah S. Bieler et al.   PLoS Computational Biology

Relation between Molecular Shape and the Morphology of Self-Assembling Aggregates: A Simulation Study

(2011) Robert Vácha et al.   BIOPHYSICAL JOURNAL

Self-replication of information-bearing nanoscale patterns

(2011) Tong Wang et al.   NATURE

Amyloid β-Protein Aggregation Produces Highly Reproducible Kinetic Data and Occurs by a Two-Phase Process

(2009) Erik Hellstrand et al.   ACS Chemical Neuroscience

Simulations of nucleation and elongation of amyloid fibrils

(2009) Jianing Zhang et al.   JOURNAL OF CHEMICAL PHYSICS

Determination of the Free Energy Landscape of α-Synuclein Using Spin Label Nuclear Magnetic Resonance Measurements

(2009) Jane R. Allison et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Secondary Nucleation and Accessible Surface in Insulin Amyloid Fibril Formation

(2008) Vito Foderà et al.   JOURNAL OF PHYSICAL CHEMISTRY B