Inhibition of amyloid beta fibril formation by monomeric human transthyretin

Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers

(2018) Ammon E. Posey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of curli assembly andEscherichia colibiofilm formation by the human systemic amyloid precursor transthyretin

(2017) Neha Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System

(2017) Joel N. Buxbaum et al.   Frontiers in Neuroscience

TANGO-Inspired Design of Anti-Amyloid Cyclic Peptides

(2016) Xiaomeng Lu et al.   ACS Chemical Neuroscience

Effect of molecular chaperones on aberrant protein oligomers in vitro: super-versus sub-stoichiometric chaperone concentrations

(2016) Sara Cappelli et al.   BIOLOGICAL CHEMISTRY

Physical determinants of the self-replication of protein fibrils

(2016) Anđela Šarić et al.   Nature Physics

Transthyretin variants with improved inhibition of β-amyloid aggregation

(2016) Parth Mangrolia et al.   PROTEIN ENGINEERING DESIGN & SELECTION

2015 Alzheimer's disease facts and figures

(2015)   Alzheimers & Dementia

On the lag phase in amyloid fibril formation

(2015) Paolo Arosio et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Prion-like features of misfolded Aβ and tau aggregates

(2015) Rodrigo Morales et al.   VIRUS RESEARCH

Titration of biologically active amyloid–β seeds in a transgenic mouse model of Alzheimer's disease

(2015) Rodrigo Morales et al.   Scientific Reports

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies

(2014) David W. Sanders et al.   NEURON

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

(2014) Georg Meisl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transthyretin as both a Sensor and a Scavenger of β-Amyloid Oligomers

(2013) Dennis T. Yang et al.   BIOCHEMISTRY

Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro

(2013) Roberta Cascella et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mechanisms of Transthyretin Inhibition of  -Amyloid Aggregation In Vitro

(2013) X. Li et al.   JOURNAL OF NEUROSCIENCE

Quantification of the Concentration of Aβ42 Propagons during the Lag Phase by an Amyloid Chain Reaction Assay

(2013) Paolo Arosio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ApoE influences amyloid-  (A ) clearance despite minimal apoE/A  association in physiological conditions

(2013) P. B. Verghese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation

(2013) S. L. Crick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ

(2013) Kanchan Garai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of the Interaction of β-Amyloid with Transthyretin Monomers and Tetramers

(2010) Jiali Du et al.   BIOCHEMISTRY

Quantification of the Thermodynamically Linked Quaternary and Tertiary Structural Stabilities of Transthyretin and Its Disease-Associated Variants: The Relationship between Stability and Amyloidosis†

(2008) Amy R. Hurshman Babbes et al.   BIOCHEMISTRY

Transthyretin binding to A-Beta peptide - Impact on A-Beta fibrillogenesis and toxicity

(2008) R. Costa et al.   FEBS LETTERS

Quasihomogeneous nucleation of amyloid beta yields numerical bounds for the critical radius, the surface tension, and the free energy barrier for nucleus formation

(2008) K. Garai et al.   JOURNAL OF CHEMICAL PHYSICS

Transthyretin Protects against A-Beta Peptide Toxicity by Proteolytic Cleavage of the Peptide: A Mechanism Sensitive to the Kunitz Protease Inhibitor

(2008) Rita Costa et al.   PLoS One

Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of A  toxicity

(2008) J. N. Buxbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA