A programmable polymer library that enables the construction of stimuli-responsive nanocarriers containing logic gates

Reactive Oxygen Species (ROS)-Based Nanomedicine

(2019) Bowen Yang et al.   CHEMICAL REVIEWS

Next-generation characterization of the Cancer Cell Line Encyclopedia

(2019) Mahmoud Ghandi et al.   NATURE

The landscape of cancer cell line metabolism

(2019) Haoxin Li et al.   NATURE MEDICINE

Chemiluminescent Probes for Activity-Based Sensing of Formaldehyde Released from Folate Degradation in Living Mice

(2018) Kevin J. Bruemmer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering a 3D DNA-Logic Gate Nanomachine for Bispecific Recognition and Computing on Target Cell Surfaces

(2018) Ruizi Peng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineered modular biomaterial logic gates for environmentally triggered therapeutic delivery

(2018) Barry A. Badeau et al.   Nature Chemistry

Metabolic exhaustion in infection, cancer and autoimmunity

(2018) E. F. McKinney et al.   NATURE IMMUNOLOGY

Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer

(2018) Leena Gandhi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer

(2018) Özge Saatci et al.   ONCOGENE

Synthetic gene circuits for the detection, elimination and prevention of disease

(2018) Ferdinand Sedlmayer et al.   Nature Biomedical Engineering

Comparing proteins and nucleic acids for next-generation biomolecular engineering

(2018) Genevieve C. Pugh et al.   Nature Reviews Chemistry

Programmable protein circuits in living cells

(2018) Xiaojing J. Gao et al.   SCIENCE

Multi-Stimuli-Responsive Polymer Particles, Films, and Hydrogels for Drug Delivery

(2018) Xiao Fu et al.   Chem

Delivery and Release of Small-Molecule Probes in Mitochondria Using Traceless Linkers

(2017) Eric K. Lei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial

(2017) Paul M Ridker et al.   LANCET

Complex cellular logic computation using ribocomputing devices

(2017) Alexander A. Green et al.   NATURE

Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene

(2017) Zhang-Hui Chen et al.   NATURE BIOTECHNOLOGY

Engineering nucleic acid structures for programmable molecular circuitry and intracellular biocomputation

(2017) Jiang Li et al.   Nature Chemistry

A spatially localized architecture for fast and modular DNA computing

(2017) Gourab Chatterjee et al.   Nature Nanotechnology

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

In vivo bioluminescence imaging of labile iron accumulation in a murine model ofAcinetobacter baumanniiinfection

(2017) Allegra T. Aron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Emerging Role of Polo-Like Kinase 1 in Epithelial-Mesenchymal Transition and Tumor Metastasis

(2017) Zheng Fu et al.   Cancers

Esterase-Sensitive Prodrugs with Tunable Release Rates and Direct Generation of Hydrogen Sulfide

(2016) Yueqin Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release

(2016) Nazila Kamaly et al.   CHEMICAL REVIEWS

IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer

(2016) Thomas A Mace et al.   GUT

Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody–drug conjugates

(2016) Leanna R. Staben et al.   Nature Chemistry

A photoactivable multi-inhibitor nanoliposome for tumour control and simultaneous inhibition of treatment escape pathways

(2016) Bryan Q. Spring et al.   Nature Nanotechnology

Cancer metabolism: a therapeutic perspective

(2016) Ubaldo E. Martinez-Outschoorn et al.   Nature Reviews Clinical Oncology

Linker Immolation Determines Cell Killing Activity of Disulfide-Linked Pyrrolobenzodiazepine Antibody–Drug Conjugates

(2016) Donglu Zhang et al.   ACS Medicinal Chemistry Letters

Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling

(2016) Jianguo Wu et al.   eLife

Alzheimer's disease: are blood and brain markers related? A systematic review

(2016) Ali T. Khan et al.   Annals of Clinical and Translational Neurology

Self-Immolative Spacers: Kinetic Aspects, Structure-Property Relationships, and Applications

(2015) Ahmed Alouane et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polymeric Nanostructures for Imaging and Therapy

(2015) Mahmoud Elsabahy et al.   CHEMICAL REVIEWS

Dendritic, Oligomeric, and Polymeric Self-Immolative Molecular Amplification

(2015) Michal E. Roth et al.   CHEMICAL REVIEWS

Hyperbranched Self-Immolative Polymers (hSIPs) for Programmed Payload Delivery and Ultrasensitive Detection

(2015) Guhuan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

(2015) J. Yun et al.   SCIENCE

Programmable and Multiparameter DNA-Based Logic Platform For Cancer Recognition and Targeted Therapy

(2014) Mingxu You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Installing logic-gate responses to a variety of biological substances in supramolecular hydrogel–enzyme hybrids

(2014) Masato Ikeda et al.   Nature Chemistry

Chain-Shattering Polymeric Therapeutics with On-Demand Drug-Release Capability

(2013) Yanfeng Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Cabozantinib (XL184), a Novel MET and VEGFR2 Inhibitor, Simultaneously Suppresses Metastasis, Angiogenesis, and Tumor Growth

(2011) F. M. Yakes et al.   MOLECULAR CANCER THERAPEUTICS

Emerging applications of stimuli-responsive polymer materials

(2010) Martien A. Cohen Stuart et al.   NATURE MATERIALS