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Site-Specific Antibody–Drug Conjugates: The Nexus of Bioorthogonal Chemistry, Protein Engineering, and Drug Development

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Natural Products as Exquisitely Potent Cytotoxic Payloads for Antibody- Drug Conjugates

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Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

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An Immunosuppressive Antibody–Drug Conjugate

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Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

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Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

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Auristatin Antibody Drug Conjugate Physical Instability and the Role of Drug Payload

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Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications

(2014) Andreas Maderna et al.   JOURNAL OF MEDICINAL CHEMISTRY

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Exploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunities

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Potent Vinblastine C20′ Ureas Displaying Additionally Improved Activity Against a Vinblastine-Resistant Cancer Cell Line

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Suitable Labels for Molecular Imaging – Influence of Dye Structure and Hydrophilicity on the Spectroscopic Properties of IgG Conjugates

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Synthesis and Evaluation of Hydrophilic Linkers for Antibody–Maytansinoid Conjugates

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Choosing an effective protein bioconjugation strategy

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Design of therapeutic proteins with enhanced stability

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Increasing Solubility of Proteins and Peptides by Site-Specific Modification with Betaine

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Design and synthesis of releasable folate–drug conjugates using a novel heterobifunctional disulfide-containing linker

(2008) Apparao Satyam   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Indibulin, a Novel Microtubule Inhibitor, Discriminates between Mature Neuronal and Nonneuronal Tubulin

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Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

(2008) Jagath R Junutula et al.   NATURE BIOTECHNOLOGY

Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters

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Prodrug Strategies in Anticancer Chemotherapy

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