Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling

TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays

(2018) Tobias Gebäck et al.   BIOTECHNIQUES

The function of FOXO1 in the late phases of the cell cycle is suppressed by PLK1-mediated phosphorylation

(2014) Chengfu Yuan et al.   CELL CYCLE

Cyr61 promotes epithelial-mesenchymal transition and tumor metastasis of osteosarcoma by Raf-1/MEK/ERK/Elk-1/TWIST-1 signaling pathway

(2014) Chun-Han Hou et al.   Molecular Cancer

Sheep, wolf, or werewolf: Cancer stem cells and the epithelial-to-mesenchymal transition

(2013) Jeffrey T. Chang et al.   CANCER LETTERS

The Role of Polo-like Kinase 1 in Carcinogenesis: Cause or Consequence?

(2013) B. D. Cholewa et al.   CANCER RESEARCH

Polo-like kinase 1 is overexpressed in colorectal cancer and participates in the migration and invasion of colorectal cancer cells

(2013) Ding-pei Han et al.   MEDICAL SCIENCE MONITOR

EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness

(2012) Ester Sánchez-Tilló et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

First-in-Human, Phase I Dose-Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of RO5126766, a First-in-Class Dual MEK/RAF Inhibitor in Patients with Solid Tumors

(2012) M. Martinez-Garcia et al.   CLINICAL CANCER RESEARCH

Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis

(2012) A Deeraksa et al.   ONCOGENE

EMT as the ultimate survival mechanism of cancer cells

(2012) Neha Tiwari et al.   SEMINARS IN CANCER BIOLOGY

PLK1 gene suppresses cell invasion of undifferentiated thyroid carcinoma through the inhibition of CD44v6, MMP-2 and MMP-9

(2012) XING-GUANG ZHANG et al.   Experimental and Therapeutic Medicine

The regulation of cell-cell adhesion during epithelial-mesenchymal transition, motility and tumor progression

(2012) Grégoire F. Le Bras et al.   Cell Adhesion & Migration

Polo-like kinase 1, on the rise from cell cycle regulation to prostate cancer development

(2012) Jijing Luo et al.   Protein & Cell

Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer

(2011) Nicole Vincent Jordan et al.   CELL CYCLE

Plk1 Phosphorylation of Orc2 Promotes DNA Replication under Conditions of Stress

(2011) B. Song et al.   MOLECULAR AND CELLULAR BIOLOGY

Circulating Tumor Cells from Patients with Advanced Prostate and Breast Cancer Display Both Epithelial and Mesenchymal Markers

(2011) A. J. Armstrong et al.   MOLECULAR CANCER RESEARCH

A MEK-independent role for CRAF in mitosis and tumor progression

(2011) Ainhoa Mielgo et al.   NATURE MEDICINE

Cell Polarity in Motion: Redefining Mammary Tissue Organization Through EMT and Cell Polarity Transitions

(2010) Nathan J. Godde et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

ERK2 but Not ERK1 Induces Epithelial-to-Mesenchymal Transformation via DEF Motif-Dependent Signaling Events

(2010) Sejeong Shin et al.   MOLECULAR CELL

Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance

(2010) Hiroshi Tanaka et al.   NATURE MEDICINE

The substrates of Plk1, beyond the functions in mitosis

(2010) X. Shawn Liu et al.   Protein & Cell

EMT, the cytoskeleton, and cancer cell invasion

(2009) Mahmut Yilmaz et al.   CANCER AND METASTASIS REVIEWS

BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity

(2009) D. Rudolph et al.   CLINICAL CANCER RESEARCH

Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice

(2009) Zheng Fu et al.   JOURNAL OF CLINICAL INVESTIGATION

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin-like Growth Factor-I-Dependent Up-regulation of ZEB1 Drives Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

(2008) T. R. Graham et al.   CANCER RESEARCH

Epithelial to mesenchymal transition (EMT) in human prostate cancer: lessons learned from ARCaP model

(2008) Haiyen E. Zhau et al.   CLINICAL & EXPERIMENTAL METASTASIS

Decreased adhesiveness, resistance to anoikis and suppression of GRP94 are integral to the survival of circulating tumor cells in prostate cancer

(2008) Edward W. Howard et al.   CLINICAL & EXPERIMENTAL METASTASIS

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL

CRAF Autophosphorylation of Serine 621 Is Required to Prevent Its Proteasome-Mediated Degradation

(2008) Catherine Noble et al.   MOLECULAR CELL

Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression

(2008) Zheng Fu et al.   NATURE CELL BIOLOGY

Transcriptional regulation of cell polarity in EMT and cancer

(2008) G Moreno-Bueno et al.   ONCOGENE

A Role for Polyploidy in the Tumorigenicity of Pim-1-Expressing Human Prostate and Mammary Epithelial Cells

(2008) Meejeon Roh et al.   PLoS One