Membrane Phospholipids and Polyphosphates as Cofactors and Binding Molecules of SERPINA12 (vaspin)

Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin

(2018) David Ulbricht et al.   BIOLOGICAL CHEMISTRY

Vaspin suppresses cytokine-induced inflammation in 3T3-L1 adipocytes via inhibition of NFκB pathway

(2018) Konstanze Zieger et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Understanding the diversity of membrane lipid composition

(2018) Takeshi Harayama et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inorganic polyphosphate, a multifunctional polyanionic protein scaffold

(2018) Lihan Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improvements to the APBS biomolecular solvation software suite

(2017) Elizabeth Jurrus et al.   PROTEIN SCIENCE

KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype

(2017) Petr Kasparek et al.   PLoS Genetics

Anti-Inflammatory Action of Keratinocyte-Derived Vaspin

(2016) Anja Saalbach et al.   AMERICAN JOURNAL OF PATHOLOGY

Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor

(2016) L. C. Wijeyewickrema et al.   BLOOD

Central administration of vaspin inhibits glucose production and augments hepatic insulin signaling in high-fat-diet-fed rat

(2016) X Luo et al.   INTERNATIONAL JOURNAL OF OBESITY

Basic Residues of β-Sheet A Contribute to Heparin Binding and Activation of Vaspin (Serpin A12)

(2016) David Ulbricht et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel assay for prothrombotic polyphosphates in plasma reveals their correlation with obesity

(2016) María J. Santi et al.   THROMBOSIS RESEARCH

Vaspin regulates the osteogenic differentiation of MC3T3-E1 through the PI3K-Akt/miR-34c loop

(2016) Yuan Liu et al.   Scientific Reports

A unique serpin P1' glutamate and a conserved  -sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin)

(2015) D. Ulbricht et al.   BIOCHEMICAL JOURNAL

The polyphosphate-factor XII pathway drives coagulation in prostate cancer-associated thrombosis

(2015) K. F. Nickel et al.   BLOOD

Vaspin inhibits cytokine-induced nuclear factor-kappa B activation and adhesion molecule expression via AMP-activated protein kinase activation in vascular endothelial cells

(2014) Chang Jung et al.   Cardiovascular Diabetology

Higher vaspin levels in subjects with obesity and type 2 diabetes mellitus: A meta-analysis

(2014) Rennan Feng et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Proteolytic activation of prochemerin by kallikrein 7 breaks an ionic linkage and results in C-terminal rearrangement

(2013) Stephan Schultz et al.   BIOCHEMICAL JOURNAL

Polyphosphate amplifies proinflammatory responses of nuclear proteins through interaction with receptor for advanced glycation end products and P2Y1 purinergic receptor

(2013) P. Dinarvand et al.   BLOOD

Vaspin inhibits kallikrein 7 by serpin mechanism

(2013) John T. Heiker et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Vaspin inhibited proinflammatory cytokine induced activation of nuclear factor-kappa B and its downstream molecules in human endothelial EA.hy926 cells

(2013) Shiwei Liu et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation

(2013) Tamas Balla   PHYSIOLOGICAL REVIEWS

New lipid interaction partners stimulate the inhibition of activated protein C by cell-penetrating protein C inhibitor

(2013) F. C. Wahlmüller et al.   THROMBOSIS AND HAEMOSTASIS

A novel adipocytokine, vaspin inhibits platelet-derived growth factor-BB-induced migration of vascular smooth muscle cells

(2012) Sukanya Phalitakul et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Connective tissue graft plus resin-modified glass ionomer restoration for the treatment of gingival recession associated with non-carious cervical lesions: microbiological and immunological results

(2012) Mauro Pedrine Santamaria et al.   Clinical Oral Investigations

Vaspin Is an Adipokine Ameliorating ER Stress in Obesity as a Ligand for Cell-Surface GRP78/MTJ-1 Complex

(2012) A. Nakatsuka et al.   DIABETES

Polyphosphate Is a Novel Pro-inflammatory Regulator of Mast Cells and Is Located in Acidocalcisomes

(2012) David Moreno-Sanchez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyphosphate elicits pro-inflammatory responses that are counteracted by activated protein C in both cellular and animal models

(2012) J.-S. BAE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions

(2012) Susanne A.I. Seidel et al.   METHODS

Vaspin protects vascular endothelial cells against free fatty acid-induced apoptosis through a phosphatidylinositol 3-kinase/Akt pathway

(2011) Chang Hee Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Central vaspin administration acutely reduces food intake and has sustained blood glucose-lowering effects

(2011) N. Klöting et al.   DIABETOLOGIA

Heparin Is a Major Activator of the Anticoagulant Serpin, Protein Z-dependent Protease Inhibitor

(2011) Xin Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of vaspin, chemerin and omentin-1 on feeding behavior and hypothalamic peptide gene expression in the rat

(2011) Luigi Brunetti et al.   PEPTIDES

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

High negative charge-to-size ratio in polyphosphates and heparin regulates factor VII-activating protease

(2009) Lars Muhl et al.   FEBS Journal

Exosite Determinants of Serpin Specificity

(2009) Peter G. W. Gettins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositide Signaling: New Tools and Insights

(2009) Tamas Balla et al.   PHYSIOLOGY

Mutations in Phosphoinositide Metabolizing Enzymes and Human Disease

(2009) Heather J. McCrea et al.   PHYSIOLOGY

Maintenance of Hormone-sensitive Phosphoinositide Pools in the Plasma Membrane Requires Phosphatidylinositol 4-Kinase IIIα

(2007) Andras Balla et al.   MOLECULAR BIOLOGY OF THE CELL