KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype
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Title
KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype
Authors
Keywords
Mouse models, Epidermis, Hair, Embryos, Inflammation, Proteases, Neonates, Phenotypes
Journal
PLoS Genetics
Volume 13, Issue 1, Pages e1006566
Publisher
Public Library of Science (PLoS)
Online
2017-01-18
DOI
10.1371/journal.pgen.1006566
References
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Related references
Note: Only part of the references are listed.- A viable mouse model for Netherton syndrome based on mosaic inactivation of the Spink5 gene
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- KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome
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- Netherton syndrome: defective kallikrein inhibition in the skin leads to skin inflammation and allergy
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- Efficient gene targeting of theRosa26locus in mouse zygotes using TALE nucleases
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- (2011) Petr Kasparek et al. TRANSGENIC RESEARCH
- Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing
- (2010) Chrystelle Bonnart et al. JOURNAL OF CLINICAL INVESTIGATION
- Par2 Inactivation Inhibits Early Production of TSLP, but Not Cutaneous Inflammation, in Netherton Syndrome Adult Mouse Model
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- New Role for LEKTI in Skin Barrier Formation: Label-Free Quantitative Proteomic Identification of Caspase 14 as a Novel Target for the Protease Inhibitor LEKTI
- (2010) Kate Bennett et al. JOURNAL OF PROTEOME RESEARCH
- Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome
- (2010) Katiuchia Uzzun Sales et al. NATURE GENETICS
- Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction
- (2009) E. A. Leclerc et al. JOURNAL OF CELL SCIENCE
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- (2009) A. Sandilands et al. JOURNAL OF CELL SCIENCE
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