Polyphosphate Is a Novel Pro-inflammatory Regulator of Mast Cells and Is Located in Acidocalcisomes

Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation

(2012) J. H. Morrissey et al.   BLOOD

Myeloma cells contain high levels of inorganic polyphosphate which is associated with nucleolar transcription

(2012) M. D. Jimenez-Nunez et al.   HAEMATOLOGICA

Acidocalcisomes

(2011) Roberto Docampo et al.   CELL CALCIUM

Mast Cells Increase Vascular Permeability by Heparin-Initiated Bradykinin Formation In Vivo

(2011) Chris Oschatz et al.   IMMUNITY

Adaptor Protein-3 (AP-3) Complex Mediates the Biogenesis of Acidocalcisomes and Is Essential for Growth and Virulence ofTrypanosoma brucei

(2011) Guozhong Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acidocalcisomes as Calcium- and Polyphosphate-Storage Compartments during Embryogenesis of the Insect Rhodnius prolixus Stahl

(2011) Isabela Ramos et al.   PLoS One

The procoagulant and proinflammatory plasma contact system

(2011) Thomas Renné   Seminars in Immunopathology

Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP

(2010) Isabela B. Ramos et al.   BIOCHEMICAL JOURNAL

Polyphosphate exerts differential effects on blood clotting, depending on polymer size

(2010) S. A. Smith et al.   BLOOD

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin

(2010) N. J. Mutch et al.   BLOOD

Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling

(2010) Sandip Patel et al.   TRENDS IN CELL BIOLOGY

Inorganic Polyphosphate: Essential for Growth and Survival

(2009) Narayana N. Rao et al.   Annual Review of Biochemistry

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Mast cells in atherogenesis: Actions and reactions

(2009) Petri T. Kovanen   Current Atherosclerosis Reports

Activation of blood coagulation in chronic urticaria: pathophysiological and clinical implications

(2009) Massimo Cugno et al.   Internal and Emergency Medicine

Ragweed pollen-mediated IgE-independent release of biogenic amines from mast cells via induction of mitochondrial dysfunction

(2009) Grzegorz Chodaczek et al.   MOLECULAR IMMUNOLOGY

Expression of Antizyme Inhibitor 2 in Mast Cells and Role of Polyamines as Selective Regulators of Serotonin Secretion

(2009) Kristiina Kanerva et al.   PLoS One

Polyphosphate enhances fibrin clot structure

(2008) S. A. Smith et al.   BLOOD

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

(2008) Emyr Lloyd-Evans et al.   NATURE MEDICINE

Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms

(2008) N. Puri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA