Effect of valine on myotube insulin sensitivity and metabolism with and without insulin resistance

Actions of chronic physiological 3-hydroxyisobuterate treatment on mitochondrial metabolism and insulin signaling in myotubes

(2019) Emily S. Lyon et al.   NUTRITION RESEARCH

Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance

(2019) Meiyi Zhou et al.   DIABETES

Leucine increases mitochondrial metabolism and lipid content without altering insulin signaling in myotubes

(2019) Madison E. Rivera et al.   BIOCHIMIE

BCAA Metabolism and Insulin Sensitivity - Dysregulated by Metabolic Status?

(2018) Nicholas P. Gannon et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Acute oral administration of L-leucine upregulates slow-fiber– and mitochondria-related genes in skeletal muscle of rats

(2018) Yoriko Sato et al.   NUTRITION RESEARCH

PGC-1α regulates alanine metabolism in muscle cells

(2018) Yukino Hatazawa et al.   PLoS One

Serum metabolite profile associated with incident type 2 diabetes in Koreans: findings from the Korean Genome and Epidemiology Study

(2018) Soo Jin Yang et al.   Scientific Reports

Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes

(2018) Adil Mardinoglu et al.   EBioMedicine

Does l-leucine supplementation cause any effect on glucose homeostasis in rodent models of glucose intolerance? A systematic review

(2018) Henver S. Brunetta et al.   AMINO ACIDS

Restoration of metabolic health by decreased consumption of branched-chain amino acids

(2017) Nicole E. Cummings et al.   JOURNAL OF PHYSIOLOGY-LONDON

Branched-chain amino acid catabolism rather than amino acids plasma concentrations is associated with diet-induced changes in insulin resistance in overweight to obese individuals

(2017) S. Haufe et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Branched-Chain Amino Acids and Insulin Metabolism: The Insulin Resistance Atherosclerosis Study (IRAS)

(2016) C. Christine Lee et al.   DIABETES CARE

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance

(2016) Cholsoon Jang et al.   NATURE MEDICINE

Associations among the plasma amino acid profile, obesity, and glucose metabolism in Japanese adults with normal glucose tolerance

(2016) Chisa Takashina et al.   Nutrition & Metabolism

The Relationship between Branched-Chain Amino Acid Related Metabolomic Signature and Insulin Resistance: A Systematic Review

(2016) Xue Zhao et al.   Journal of Diabetes Research

Alterations of plasma metabolite profiles related to adipose tissue distribution and cardiometabolic risk

(2015) Marie Michèle Boulet et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Diabetes risk and amino acid profiles: cross-sectional and prospective analyses of ethnicity, amino acids and diabetes in a South Asian and European cohort from the SABRE (Southall And Brent REvisited) Study

(2015) Therese Tillin et al.   DIABETOLOGIA

Association between insulin resistance and plasma amino acid profile in non-diabetic Japanese subjects

(2015) Chizumi Yamada et al.   Journal of Diabetes Investigation

Simultaneous quantification of salivary 3-hydroxybutyrate, 3-hydroxyisobutyrate, 3-hydroxy-3-methylbutyrate, and 2-hydroxybutyrate as possible markers of amino acid and fatty acid catabolic pathways by LC–ESI–MS/MS

(2015) Teruo Miyazaki et al.   SpringerPlus

Effects of individual branched-chain amino acids deprivation on insulin sensitivity and glucose metabolism in mice

(2014) Fei Xiao et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

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(2014) Christopher J. Lynch et al.   Nature Reviews Endocrinology

PGC-1α-Mediated Branched-Chain Amino Acid Metabolism in the Skeletal Muscle

(2014) Yukino Hatazawa et al.   PLoS One

Bolus ingestion of individual branched-chain amino acids alters plasma amino acid profiles in young healthy men

(2014) Takuya Matsumoto et al.   SpringerPlus

Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

(2013) Denise E. Lackey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Leucine Facilitates Insulin Signaling through a GαiProtein-dependent Signaling Pathway in Hepatocytes

(2013) Xuefeng Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance

(2012) Christopher B. Newgard   Cell Metabolism

Metabolic Signatures of Insulin Resistance in 7,098 Young Adults

(2012) P. Wurtz et al.   DIABETES

Differential effect of long-term leucine supplementation on skeletal muscle and adipose tissue in old rats: an insulin signaling pathway approach

(2011) Gilbert Zeanandin et al.   AGE

Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men

(2010) E. S. Tai et al.   DIABETOLOGIA

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Relationships Between Circulating Metabolic Intermediates and Insulin Action in Overweight to Obese, Inactive Men and Women

(2009) K. M. Huffman et al.   DIABETES CARE